SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1jym PEPTIDE DEFORMYLASE
(Plasmodium
falciparum) 		5 / 10 ILE A 160
GLY A 154
CYH A 155
LEU A  75
ILE A 207
 None
None
CO  A 300 (-2.2A)
None
None
 1.34A 3adsA-1jymA:
undetectable		 3adsA-1jymA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1298_1
(GERANYLTRANSTRANSFER
ASE)		 1jym PEPTIDE DEFORMYLASE
(Plasmodium
falciparum) 		4 / 4 ILE A 172
PHE A 198
GLN A 195
ASP A 199
 None
 1.35A 4umjA-1jymA:
undetectable		 4umjA-1jymA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1jym PEPTIDE DEFORMYLASE
(Plasmodium
falciparum) 		4 / 5 ILE A 141
PHE A 194
ASN A  83
TYR A 175
 None
 1.19A 6a93B-1jymA:
undetectable		 6a93B-1jymA:
18.57