SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		5 / 10 ALA A  27
GLU A  28
LEU A  40
ILE A  56
HIS A  60
 None
 1.38A 1qkuA-1jznA:
undetectable		 1qkuA-1jznA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		5 / 10 ALA A  27
GLU A  28
LEU A  40
ILE A  56
HIS A  60
 None
 1.38A 1qkuB-1jznA:
undetectable		 1qkuB-1jznA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		5 / 10 ALA A  27
GLU A  28
LEU A  40
ILE A  56
HIS A  60
 None
 1.38A 1qkuC-1jznA:
undetectable		 1qkuC-1jznA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 7 ILE A  68
SER A  85
TYR A  89
TRP A 118
 None
 0.91A 2xz5D-1jznA:
0.0
2xz5E-1jznA:
0.0		 2xz5D-1jznA:
19.00
2xz5E-1jznA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		3 / 3 TYR A 100
ASP A 120
ASP A  93
 GAL  A 137 ( 4.1A)
CA  A1138 ( 3.0A)
None
 0.87A 3ou7B-1jznA:
undetectable		 3ou7B-1jznA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 5 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.21A 5dzkb-1jznA:
undetectable
5dzkp-1jznA:
undetectable		 5dzkb-1jznA:
18.02
5dzkp-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 6 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.25A 5dzkB-1jznA:
undetectable
5dzkP-1jznA:
undetectable		 5dzkB-1jznA:
18.02
5dzkP-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 5 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.20A 5dzkc-1jznA:
undetectable
5dzkq-1jznA:
undetectable		 5dzkc-1jznA:
18.02
5dzkq-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 7 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.02A 5dzkD-1jznA:
undetectable
5dzkR-1jznA:
undetectable		 5dzkD-1jznA:
18.02
5dzkR-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 5 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.02A 5dzkf-1jznA:
undetectable
5dzkt-1jznA:
undetectable		 5dzkf-1jznA:
18.02
5dzkt-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 8 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.15A 5dzkF-1jznA:
undetectable
5dzkT-1jznA:
undetectable		 5dzkF-1jznA:
18.02
5dzkT-1jznA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1jzn GALACTOSE-SPECIFIC
LECTIN
(Crotalus
atrox) 		4 / 6 SER A  42
ALA A  41
HIS A  44
LEU A  13
 NA  A1139 (-2.9A)
None
None
None
 1.16A 5dzkg-1jznA:
undetectable
5dzku-1jznA:
undetectable		 5dzkg-1jznA:
18.02
5dzku-1jznA:
15.38