SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		4 / 7 LEU A 173
LEU A 177
PHE A  93
LEU A  74
 None
 0.92A 2vq5B-1jzoA:
0.1		 2vq5B-1jzoA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		4 / 4 LEU A 173
ASP A  18
VAL A  36
THR A  63
 None
 1.07A 3cyxB-1jzoA:
0.0		 3cyxB-1jzoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		4 / 7 ASP A  95
PHE A 123
GLY A 127
THR A  97
 None
 1.13A 3vnsA-1jzoA:
undetectable		 3vnsA-1jzoA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		5 / 11 SER A 101
LEU A 104
ILE A 139
VAL A  92
VAL A 179
 None
 0.94A 3w67A-1jzoA:
undetectable		 3w67A-1jzoA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		5 / 11 TYR A 120
VAL A  92
ILE A  90
MET A 202
LEU A 206
 None
 1.20A 4lhmA-1jzoA:
undetectable		 4lhmA-1jzoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		3 / 3 ILE A  90
VAL A  92
PRO A 183
 None
 0.68A 5uunA-1jzoA:
3.2		 5uunA-1jzoA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		4 / 6 PRO A 183
GLY A 195
TYR A 100
VAL A  92
 None
 0.98A 5x80A-1jzoA:
undetectable
5x80B-1jzoA:
undetectable		 5x80A-1jzoA:
23.87
5x80B-1jzoA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC
(Escherichia
coli) 		4 / 7 VAL A  92
PRO A 183
GLY A 195
TYR A 100
 None
 1.02A 5x80C-1jzoA:
undetectable
5x80D-1jzoA:
undetectable		 5x80C-1jzoA:
23.87
5x80D-1jzoA:
23.87