SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1jzt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 11 ILE A  15
LEU A  19
VAL A 200
THR A 199
PHE A 221
 None
 1.48A 1tw4A-1jztA:
0.0		 1tw4A-1jztA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 PRO A 152
ILE A  64
LEU A 125
LEU A 160
THR A 133
 None
 1.08A 3a50E-1jztA:
undetectable		 3a50E-1jztA:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 8 ALA A  12
ASP A  16
LEU A  19
ASP A 173
LEU A 198
LYS A 202
 None
 0.72A 3roxA-1jztA:
34.8		 3roxA-1jztA:
39.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROX_A_TEPA266_1
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 8 ALA A  12
LEU A  19
ASP A 173
LEU A 198
THR A 199
LYS A 202
 None
 0.31A 3roxA-1jztA:
34.8		 3roxA-1jztA:
39.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		6 / 6 ASP A  16
LEU A  19
ALA A  35
ASP A  73
LEU A 198
THR A 199
 None
 0.47A 3rozA-1jztA:
34.6		 3rozA-1jztA:
39.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 195
VAL A 137
PHE A 141
GLY A 177
 None
 0.86A 4r3aA-1jztA:
undetectable		 4r3aA-1jztA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 4 ASN A  70
VAL A 137
THR A 176
ILE A 190
 None
 1.40A 4retA-1jztA:
3.3		 4retA-1jztA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 4 ASN A  70
VAL A 137
THR A 176
ILE A 190
 None
 1.40A 4retC-1jztA:
3.2		 4retC-1jztA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 5 VAL A 200
VAL A 217
GLY A 218
PHE A 235
 None
 1.08A 5d4nA-1jztA:
undetectable
5d4nC-1jztA:
0.0		 5d4nA-1jztA:
18.29
5d4nC-1jztA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 PRO A 175
ILE A 166
SER A 205
 None
 0.79A 5fsaA-1jztA:
0.0		 5fsaA-1jztA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 7 GLY A  72
VAL A  90
ILE A  64
VAL A  63
 None
 0.77A 5ik1A-1jztA:
undetectable		 5ik1A-1jztA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  74
GLY A  72
ASP A 138
VAL A 137
ALA A  35
 None
 1.12A 5kpcB-1jztA:
4.4		 5kpcB-1jztA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 190
LEU A 160
PRO A 188
SER A 186
GLY A 177
 None
 1.19A 5nnaA-1jztA:
0.0		 5nnaA-1jztA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 190
LEU A 160
PRO A 188
SER A 186
GLY A 177
 None
 1.17A 5nnaB-1jztA:
0.3		 5nnaB-1jztA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 190
LEU A 160
PRO A 188
SER A 186
GLY A 177
 None
 1.11A 5nnaC-1jztA:
undetectable		 5nnaC-1jztA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  15
LEU A  19
PHE A  26
LEU A  34
ALA A  35
 None
 0.95A 5y7pB-1jztA:
0.0		 5y7pB-1jztA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  15
LEU A  19
PHE A  26
LEU A  34
ALA A  35
 None
 0.97A 5y7pD-1jztA:
0.0		 5y7pD-1jztA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		4 / 8 ILE A  15
PHE A  26
LEU A  34
ALA A  35
 None
 0.86A 5y7pE-1jztA:
0.0		 5y7pE-1jztA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 10 ILE A  15
LEU A  19
PHE A  26
LEU A  34
ALA A  35
 None
 0.96A 5y7pH-1jztA:
undetectable		 5y7pH-1jztA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  34
GLY A 219
VAL A 137
VAL A 172
ASP A 173
 None
 1.36A 6bxlB-1jztA:
2.9		 6bxlB-1jztA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1jzt HYPOTHETICAL 27.5
KDA PROTEIN IN
SPX19-GCR2
INTERGENIC REGION
(Saccharomyces
cerevisiae) 		3 / 3 LEU A  31
GLY A 219
PHE A 232
 None
 0.56A 6exiC-1jztA:
4.2		 6exiC-1jztA:
13.88