SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 12 VAL A 168
CYH A 165
SER A 182
LEU A 181
THR A 180
None
1.20A 3a35A-1k0rA:
1.1
3a35A-1k0rA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 12 VAL A 168
CYH A 165
SER A 182
LEU A 181
THR A 180
None
1.18A 3a35B-1k0rA:
2.5
3a35B-1k0rA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 12 VAL A 168
CYH A 165
SER A 182
LEU A 181
THR A 180
None
1.15A 3a3bA-1k0rA:
0.9
3a3bA-1k0rA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 12 ILE A 303
LEU A 299
ASP A 322
VAL A 294
VAL A 277
None
0.69A 3rukB-1k0rA:
undetectable
3rukB-1k0rA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
1k0r NUSA
(Mycobacterium
tuberculosis)
4 / 5 ASN A 309
ALA A 275
PRO A 274
ALA A 271
None
1.34A 3twpD-1k0rA:
undetectable
3twpD-1k0rA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)
1k0r NUSA
(Mycobacterium
tuberculosis)
4 / 6 ILE A 207
ILE A 255
SER A 218
LEU A 316
None
0.94A 4m51A-1k0rA:
0.0
4m51A-1k0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NPT_A_017A401_1
(PROTEASE)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 9 ALA A 231
ILE A 236
GLY A 237
ILE A 207
VAL A 222
None
0.99A 4nptA-1k0rA:
undetectable
4nptA-1k0rA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 10 ALA A 290
VAL A 280
VAL A 294
ALA A 275
ALA A 310
None
1.09A 6h1lA-1k0rA:
0.0
6h1lA-1k0rA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_B_FJQB501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)
1k0r NUSA
(Mycobacterium
tuberculosis)
5 / 11 ALA A 290
VAL A 280
VAL A 294
ALA A 275
ALA A 310
None
1.00A 6h1lB-1k0rA:
undetectable
6h1lB-1k0rA:
20.99