SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 9 VAL A 172
VAL A 184
LEU A 168
ALA A 215
LEU A 216
 None
 1.19A 1eqgA-1k1bA:
undetectable		 1eqgA-1k1bA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 131
VAL A 179
LEU A 182
ALA A 188
 None
 0.86A 1fiqC-1k1bA:
undetectable		 1fiqC-1k1bA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 202
ASN A 231
ALA A 258
LEU A 253
 None
 0.92A 1hwiD-1k1bA:
undetectable		 1hwiD-1k1bA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 132
ASN A 161
ALA A 188
LEU A 183
 None
 1.05A 1hwiC-1k1bA:
undetectable		 1hwiC-1k1bA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 8 HIS A 202
ASN A 231
ALA A 258
LEU A 253
 None
 0.92A 1hwiC-1k1bA:
undetectable		 1hwiC-1k1bA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 10 ALA A 200
LEU A 252
LEU A 253
LEU A 213
ARG A 214
 None
 1.19A 2riwA-1k1bA:
0.0
2riwB-1k1bA:
undetectable		 2riwA-1k1bA:
22.59
2riwB-1k1bA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 9 LEU A 281
LEU A 288
ALA A 275
LEU A 272
ALA A 304
 None
 1.09A 2vcvD-1k1bA:
undetectable		 2vcvD-1k1bA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 9 LEU A 281
LEU A 288
ALA A 275
LEU A 272
ALA A 304
 None
 1.08A 2vcvI-1k1bA:
undetectable		 2vcvI-1k1bA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 6 THR A 174
VAL A 172
CYH A 212
SER A 209
 None
 1.11A 3b6rB-1k1bA:
undetectable		 3b6rB-1k1bA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 181
THR A 166
THR A 224
 None
 0.81A 3k2hB-1k1bA:
undetectable		 3k2hB-1k1bA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 4 ALA A 262
HIS A 239
HIS A 274
PRO A 271
 None
 1.46A 3mbgA-1k1bA:
undetectable		 3mbgA-1k1bA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 4 ALA A 262
HIS A 239
HIS A 274
PRO A 271
 None
 1.46A 3mbgC-1k1bA:
undetectable		 3mbgC-1k1bA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 5 ARG A 311
VAL A 284
LEU A 281
SER A 280
 None
 1.16A 4e1gA-1k1bA:
0.9		 4e1gA-1k1bA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 7 HIS A 290
VAL A 250
ILE A 260
ALA A 292
 None
 0.87A 4lv9A-1k1bA:
undetectable		 4lv9A-1k1bA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 305
SER A 307
LEU A 316
LEU A 350
 None
 1.18A 4n09B-1k1bA:
undetectable		 4n09B-1k1bA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 305
SER A 307
LEU A 316
LEU A 350
 None
 1.18A 4n09D-1k1bA:
undetectable		 4n09D-1k1bA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 286
LEU A 238
HIS A 239
ILE A 273
 None
 0.89A 4ok1A-1k1bA:
undetectable		 4ok1A-1k1bA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 170
ILE A 133
HIS A 132
VAL A 136
 None
 1.22A 4xyzA-1k1bA:
undetectable		 4xyzA-1k1bA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 10 ALA A 200
ASP A 158
ALA A 171
SER A 219
ALA A 215
 None
 1.13A 4zbrA-1k1bA:
undetectable		 4zbrA-1k1bA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 242
GLU A 245
LEU A 272
ALA A 275
LEU A 281
 None
 1.14A 5nd4B-1k1bA:
undetectable		 5nd4B-1k1bA:
20.43