SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 PHE A 656
LEU A 423
TYR A 432
LEU A 551
ASP A 554
 None
 1.44A 1e7wA-1k1xA:
undetectable		 1e7wA-1k1xA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 GLN A 489
TYR A 502
ARG A 503
 None
 0.87A 1gtbA-1k1xA:
0.0		 1gtbA-1k1xA:
16.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K1Y_A_ACRA660_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		11 / 12 HIS A  11
GLU A 123
ARG A 124
PHE A 187
ASP A 213
ASP A 214
LYS A 217
TYR A 272
GLU A 274
TRP A 278
TRP A 357
 None
 0.52A 1k1yA-1k1xA:
56.9		 1k1yA-1k1xA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1K1Y_A_ACRA660_2
(4-ALPHA-GLUCANOTRANS
FERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 4 HIS A  13
ARG A 182
TRP A 221
ASP A 354
 None
 0.33A 1k1yA-1k1xA:
56.9		 1k1yA-1k1xA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 GLU A 236
LYS A 192
VAL A 190
 None
 0.96A 1l2iA-1k1xA:
0.0		 1l2iA-1k1xA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 6 PRO A 587
GLU A 477
PHE A 619
ARG A 438
 None
 1.46A 1oniA-1k1xA:
undetectable
1oniC-1k1xA:
undetectable		 1oniA-1k1xA:
12.75
1oniC-1k1xA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ILE A  10
VAL A 228
TRP A 233
LEU A 234
PHE A 211
 None
 1.33A 1p5zB-1k1xA:
undetectable		 1p5zB-1k1xA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 4 LEU A 134
ILE A 177
ARG A 182
TYR A 141
 None
 1.47A 1rk3A-1k1xA:
0.0		 1rk3A-1k1xA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 10 ILE A 364
ALA A 355
TYR A 320
ILE A 634
PRO A 437
 None
 1.31A 2dm6A-1k1xA:
undetectable
2dm6B-1k1xA:
undetectable		 2dm6A-1k1xA:
20.27
2dm6B-1k1xA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ILE A  10
VAL A 228
TRP A 233
LEU A 234
PHE A 211
 None
 1.31A 2no0B-1k1xA:
1.2		 2no0B-1k1xA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 7 ILE A 634
PRO A 471
ILE A 470
LEU A 478
ILE A 474
 None
 1.31A 2q83A-1k1xA:
0.7		 2q83A-1k1xA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 LEU A 267
PRO A 268
ARG A 124
 None
 0.43A 2qd4B-1k1xA:
undetectable		 2qd4B-1k1xA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 LEU A 267
PRO A 268
ARG A 124
 None
 0.53A 2qd5A-1k1xA:
0.1		 2qd5A-1k1xA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 ARG A 398
GLN A 516
PRO A 517
 None
 1.00A 2qhfA-1k1xA:
0.0		 2qhfA-1k1xA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 10 ASP A 354
SER A 334
ILE A 347
LEU A  54
GLY A  84
 None
 1.37A 2v0mA-1k1xA:
undetectable		 2v0mA-1k1xA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ILE A  10
VAL A 228
TRP A 233
LEU A 234
PHE A 211
 None
 1.31A 2ziaB-1k1xA:
undetectable		 2ziaB-1k1xA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 5 LEU A 134
ILE A 177
ARG A 182
TYR A 141
 None
 1.43A 2zlcA-1k1xA:
0.0		 2zlcA-1k1xA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ILE A 493
GLN A 489
ASN A 577
THR A 641
PHE A 619
 None
 1.33A 3em0B-1k1xA:
2.2		 3em0B-1k1xA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 ARG A 370
PRO A  53
SER A  51
GLY A  17
 None
 0.98A 3hcrB-1k1xA:
undetectable		 3hcrB-1k1xA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 GLU A  87
HIS A  11
THR A 122
 None
 0.86A 3hkuA-1k1xA:
undetectable		 3hkuA-1k1xA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 VAL A 210
VAL A  46
ILE A 185
MET A  35
 None
 1.24A 3ms9B-1k1xA:
undetectable		 3ms9B-1k1xA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 5 VAL A 580
PHE A 656
ILE A 608
PHE A 556
 None
 1.07A 3owxB-1k1xA:
0.0		 3owxB-1k1xA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 GLY A 169
TYR A 266
PRO A 128
GLU A 129
 None
 1.03A 3s3mA-1k1xA:
undetectable		 3s3mA-1k1xA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 GLY A 169
TYR A 266
PRO A 128
GLU A 129
 None
 1.02A 3s3nA-1k1xA:
undetectable		 3s3nA-1k1xA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		3 / 3 ARG A 182
PRO A 186
PHE A 211
 None
 0.86A 3thrC-1k1xA:
0.6		 3thrC-1k1xA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 11 TYR A 356
PHE A 317
ILE A  93
ARG A 338
ILE A 347
 None
 1.39A 3vawA-1k1xA:
undetectable		 3vawA-1k1xA:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 GLY A   9
ILE A 177
VAL A 143
PHE A 211
ASP A 214
 None
 1.16A 4a6eA-1k1xA:
undetectable		 4a6eA-1k1xA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ILE A 401
LEU A 529
GLY A 418
TYR A 560
ALA A 558
 None
 1.29A 4eb4A-1k1xA:
undetectable		 4eb4A-1k1xA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 ILE A  58
LEU A  54
ILE A  80
GLY A 215
 None
 0.88A 4hb6A-1k1xA:
undetectable		 4hb6A-1k1xA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 ARG A 188
VAL A 228
TRP A 227
GLU A 236
 None
 1.32A 4jseA-1k1xA:
0.0
4jseB-1k1xA:
0.0		 4jseA-1k1xA:
21.29
4jseB-1k1xA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 PRO A  15
ILE A  10
HIS A 212
TYR A  31
LEU A  54
 None
 1.28A 4l9qA-1k1xA:
0.1		 4l9qA-1k1xA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 PRO A  15
ILE A  10
HIS A 212
TYR A  31
LEU A  54
 None
 1.21A 4l9qB-1k1xA:
0.0		 4l9qB-1k1xA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 TRP A 221
THR A 224
PHE A 218
SER A  30
 None
 1.33A 4o4dA-1k1xA:
0.0		 4o4dA-1k1xA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 5 HIS A 491
VAL A 574
GLU A 575
VAL A 514
 None
 1.06A 4p6vB-1k1xA:
0.0
4p6vE-1k1xA:
0.0		 4p6vB-1k1xA:
21.35
4p6vE-1k1xA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 10 ILE A  10
LEU A  66
LEU A  72
MET A  35
PHE A  34
 None
 1.36A 4r3aB-1k1xA:
undetectable		 4r3aB-1k1xA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 GLU A 216
LEU A 366
GLY A  20
PHE A  23
LEU A  54
 None
 1.20A 4retC-1k1xA:
0.6		 4retC-1k1xA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 ASP A 146
TYR A 196
ASP A 178
ILE A   4
 None
 1.06A 4xjeA-1k1xA:
0.0		 4xjeA-1k1xA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 ARG A  98
ILE A 102
PRO A  88
ILE A  93
 None
 1.07A 4z4eA-1k1xA:
0.0		 4z4eA-1k1xA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 ARG A  98
ILE A 102
PRO A  88
ILE A  93
 None
 1.08A 4z4gA-1k1xA:
0.6		 4z4gA-1k1xA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 4 ILE A 603
ARG A 427
TYR A 432
GLU A 658
 None
 1.41A 4zzbD-1k1xA:
undetectable		 4zzbD-1k1xA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 6 LYS A 622
ASP A 481
PRO A 367
TYR A 365
 None
 1.24A 5bmvB-1k1xA:
undetectable		 5bmvB-1k1xA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 TYR A 560
TYR A 518
SER A 419
LEU A 488
 None
 1.12A 5bphB-1k1xA:
undetectable		 5bphB-1k1xA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 10 LEU A 134
ALA A 137
GLU A 136
LEU A  99
GLY A  84
 None
 1.06A 5dxbA-1k1xA:
0.3		 5dxbA-1k1xA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 GLY A  52
PHE A 238
PHE A  34
ILE A 241
HIS A  49
 None
 1.19A 5fsaB-1k1xA:
0.0		 5fsaB-1k1xA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		5 / 12 ALA A 486
ASP A 394
PHE A 421
SER A 323
GLU A 322
 None
CA  A1601 (-3.3A)
None
None
None
 1.09A 5hfjF-1k1xA:
undetectable		 5hfjF-1k1xA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 ARG A 607
GLU A 609
GLY A 555
ASP A 554
 None
 1.11A 5kgpA-1k1xA:
0.1		 5kgpA-1k1xA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 9 PHE A   8
VAL A  81
ASN A  12
ASP A 214
 None
 0.97A 5lg3I-1k1xA:
0.2		 5lg3I-1k1xA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 HIS A  11
PHE A 218
PHE A  34
MET A  35
 None
 1.11A 5y2tB-1k1xA:
0.0		 5y2tB-1k1xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 7 VAL A 210
VAL A 208
PHE A 160
ASP A 146
 None
 0.80A 5yf9B-1k1xA:
undetectable		 5yf9B-1k1xA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 8 LEU A 643
GLU A 497
TRP A 617
THR A 641
 None
 1.14A 6c71B-1k1xA:
undetectable		 6c71B-1k1xA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1k1x 4-ALPHA-GLUCANOTRANS
FERASE
(Thermococcus
litoralis) 		4 / 5 TYR A 502
ILE A 603
MET A 642
GLY A 573
 None
 1.08A 6hd6A-1k1xA:
undetectable		 6hd6A-1k1xA:
8.91