SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k25'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1502_0 (FERROCHELATASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 8	LEU A 714 PRO A 646 VAL A 663 GLY A 664	None	0.94A	1hrkA-1k25A: undetectable	1hrkA-1k25A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_B_CHDB2502_0 (FERROCHELATASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 8	LEU A 714 PRO A 646 VAL A 663 GLY A 664	None	0.92A	1hrkB-1k25A: undetectable	1hrkB-1k25A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_D_T44D129_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.84A	1ictB-1k25A: undetectable	1ictB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_B_RBFB301_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	LEU A 223 ALA A 88 GLY A 199 SER A 217 GLU A 220	None	1.25A	2a58A-1k25A: undetectable 2a58B-1k25A: undetectable	2a58A-1k25A: 14.31 2a58B-1k25A: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_C_RBFC302_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	LEU A 223 ALA A 88 GLY A 199 SER A 217 GLU A 220	None	1.25A	2a58B-1k25A: undetectable 2a58C-1k25A: undetectable	2a58B-1k25A: 14.31 2a58C-1k25A: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_E_RBFE304_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	LEU A 223 ALA A 88 GLY A 199 SER A 217 GLU A 220	None	1.25A	2a58D-1k25A: undetectable 2a58E-1k25A: undetectable	2a58D-1k25A: 14.31 2a58E-1k25A: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DM6_A_IMNA1401_1 (NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGEN ASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 10	TYR A 262 ALA A 624 ILE A 480 PRO A 682 ILE A 657	None	1.34A	2dm6A-1k25A: undetectable 2dm6B-1k25A: undetectable	2dm6A-1k25A: 19.21 2dm6B-1k25A: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	TYR A 586 LEU A 462 ILE A 468 VAL A 341 TYR A 333	None	1.19A	2g72B-1k25A: undetectable	2g72B-1k25A: 16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ROX_B_T44B128_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.89A	2roxB-1k25A: undetectable	2roxB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_C_SVRC507_2 (PHOSPHOLIPASE A2)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	VAL A 423 GLN A 436 PHE A 419 ARG A 426	None	1.13A	3bjwF-1k25A: 0.0	3bjwF-1k25A: 9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CFQ_B_DIFB1_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.86A	3cfqA-1k25A: undetectable 3cfqB-1k25A: undetectable	3cfqA-1k25A: 10.36 3cfqB-1k25A: 10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D2T_A_1FLA502_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.83A	3d2tA-1k25A: undetectable	3d2tA-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDY_A_RBFA187_1 (LUMAZINE PROTEIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	VAL A 85 SER A 267 ILE A 198 ALA A 194 THR A 305	None	1.24A	3ddyA-1k25A: 0.0	3ddyA-1k25A: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FSU_A_C2FA995_0 (5,10-METHYLENETETRAH YDROFOLATE REDUCTASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	THR A 264 LEU A 429 SER A 217 LEU A 328 THR A 459	None	1.25A	3fsuA-1k25A: undetectable	3fsuA-1k25A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCP_B_CHDB4_0 (FERROCHELATASE, MITOCHONDRIAL)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	3 / 3	GLY A 422 PRO A 438 LEU A 416	None	0.58A	3hcpB-1k25A: 0.0	3hcpB-1k25A: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_H_SAMH226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	GLY A 453 VAL A 456 PRO A 335 ALA A 446 LEU A 413	None	0.96A	3ku1H-1k25A: undetectable	3ku1H-1k25A: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_B_SAMB401_1 (MNMC2)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 4	GLU A 316 ASP A 278 ASP A 313 GLU A 274	None	1.48A	3vywB-1k25A: 0.0	3vywB-1k25A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7B_A_TCWA1126_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.81A	4d7bB-1k25A: 0.0	4d7bB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7B_B_TCWB1126_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.76A	4d7bA-1k25A: undetectable	4d7bA-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DTZ_A_LDPA501_1 (CYTOCHROME P450 BM3 VARIANT 8C8)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	PHE A 603 ALA A 572 LEU A 585 THR A 574	None	0.95A	4dtzA-1k25A: 0.0	4dtzA-1k25A: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I89_A_1FLA201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.81A	4i89A-1k25A: undetectable	4i89A-1k25A: 12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKJ_B_SUZB201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 8	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.89A	4ikjA-1k25A: undetectable 4ikjB-1k25A: undetectable	4ikjA-1k25A: 10.80 4ikjB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKK_A_SUZA201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 8	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.90A	4ikkA-1k25A: undetectable 4ikkB-1k25A: undetectable	4ikkA-1k25A: 10.80 4ikkB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKK_B_SUZB201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.94A	4ikkA-1k25A: undetectable 4ikkB-1k25A: undetectable	4ikkA-1k25A: 10.80 4ikkB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KMU_C_RFPC1401_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	GLN A 306 ASP A 81 LEU A 328 ILE A 301 ARG A 82	None	1.26A	4kmuC-1k25A: 0.0	4kmuC-1k25A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4S0V_A_SUVA2001_1 (HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	THR A 292 VAL A 294 GLN A 458 THR A 457 GLN A 460	None	1.49A	4s0vA-1k25A: undetectable	4s0vA-1k25A: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBS_A_DIFA502_1 (PENTALENIC ACID SYNTHASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	VAL A 663 LEU A 746 LEU A 714 LEU A 718 ILE A 716	None	1.33A	4ubsA-1k25A: 0.0	4ubsA-1k25A: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA407_0 (FAD:PROTEIN FMN TRANSFERASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	3 / 3	ASP A 90 GLY A 77 ASP A 260	None	0.62A	4xdtA-1k25A: 0.0	4xdtA-1k25A: 19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YGF_A_AZMA303_1 (ALPHA-CARBONIC ANHYDRASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 11	VAL A 546 VAL A 544 LEU A 608 THR A 605 ALA A 604	None	1.49A	4ygfA-1k25A: undetectable	4ygfA-1k25A: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YHA_B_MZMB303_1 (ALPHA-CARBONIC ANHYDRASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 10	VAL A 546 VAL A 544 LEU A 608 THR A 605 ALA A 604	None	1.48A	4yhaB-1k25A: undetectable	4yhaB-1k25A: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BOJ_A_4TXA201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.82A	5bojA-1k25A: undetectable	5bojA-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BOJ_B_4TXB201_1 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.78A	5bojB-1k25A: 0.0	5bojB-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CF9_B_NCAB302_0 (RIBOSOME-INACTIVATIN G PROTEIN MOMORDIN I)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	ILE A 198 GLY A 218 ILE A 79 ALA A 88 ARG A 186	None	1.41A	5cf9B-1k25A: undetectable	5cf9B-1k25A: 17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_A_ACTA1231_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	3 / 3	ARG A 733 THR A 411 ASP A 414	None	0.81A	5g5gA-1k25A: 0.0 5g5gB-1k25A: 0.0	5g5gA-1k25A: 15.91 5g5gB-1k25A: 18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HES_A_032A401_1 (MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	6 / 12	GLY A 500 VAL A 503 ALA A 508 ILE A 348 THR A 511 ALA A 469	None	1.43A	5hesA-1k25A: undetectable	5hesA-1k25A: 18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HHJ_B_GLYB404_0 (RETRON-TYPE REVERSE TRANSCRIPTASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 4	GLN A 452 ALA A 551 GLN A 552 THR A 550	None	1.46A	5hhjB-1k25A: 0.0	5hhjB-1k25A: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4I_A_6J3A201_0 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.80A	5l4iA-1k25A: undetectable	5l4iA-1k25A: 10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L4I_B_6J3B201_0 (TRANSTHYRETIN)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 6	LEU A 585 ALA A 291 LEU A 293 THR A 305	None	0.77A	5l4iB-1k25A: 0.0	5l4iB-1k25A: 10.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5OJ0_A_9WTA801_0 (PENICILLIN-BINDING PROTEIN 2X)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	ASN A 397 SER A 548 GLY A 549 THR A 550 GLN A 552	None	1.18A	5oj0A-1k25A: 48.9	5oj0A-1k25A: 88.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5OJ0_A_9WTA801_0 (PENICILLIN-BINDING PROTEIN 2X)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 12	GLN A 447 GLN A 452 SER A 548 GLY A 549 THR A 550	None	0.50A	5oj0A-1k25A: 48.9	5oj0A-1k25A: 88.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_B_EZLB303_1 (ALPHA-CARBONIC ANHYDRASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	VAL A 546 VAL A 544 LEU A 608 THR A 605 ALA A 604	None	1.47A	5tt3B-1k25A: undetectable	5tt3B-1k25A: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_E_EZLE303_1 (ALPHA-CARBONIC ANHYDRASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	VAL A 546 VAL A 544 LEU A 608 THR A 605 ALA A 604	None	1.50A	5tt3E-1k25A: undetectable	5tt3E-1k25A: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TT3_G_EZLG303_1 (ALPHA-CARBONIC ANHYDRASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	VAL A 546 VAL A 544 LEU A 608 THR A 605 ALA A 604	None	1.50A	5tt3G-1k25A: undetectable	5tt3G-1k25A: 15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 4	VAL A 503 LEU A 344 ASN A 470 ASP A 471	None	1.16A	5vcyA-1k25A: undetectable	5vcyA-1k25A: 19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_A_9F2A302_1 (BETA-LACTAMASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	THR A 459 ILE A 301 TYR A 586 THR A 588 THR A 290	None	1.40A	6b5yA-1k25A: 13.1 6b5yB-1k25A: 6.9	6b5yA-1k25A: 9.69 6b5yB-1k25A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_A_9F2A302_1 (BETA-LACTAMASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	THR A 459 ILE A 301 TYR A 586 THR A 588 THR A 290	None	1.41A	6b68A-1k25A: 13.2 6b68B-1k25A: 13.1	6b68A-1k25A: 9.69 6b68B-1k25A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_A_9F2A302_1 (BETA-LACTAMASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	THR A 459 ILE A 301 TYR A 586 THR A 588 THR A 290	None	1.41A	6b6aA-1k25A: 13.1 6b6aB-1k25A: 13.2	6b6aA-1k25A: 9.69 6b6aB-1k25A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_C_9F2C302_1 (BETA-LACTAMASE)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	THR A 459 ILE A 301 TYR A 586 THR A 588 THR A 290	None	1.43A	6b6aC-1k25A: 13.1 6b6aD-1k25A: 13.1	6b6aC-1k25A: 9.69 6b6aD-1k25A: 9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_F_EY4F500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	ALA A 707 THR A 706 GLN A 728 VAL A 727	None	0.94A	6cduF-1k25A: undetectable 6cduJ-1k25A: undetectable	6cduF-1k25A: 18.31 6cduJ-1k25A: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_H_EY4H500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	4 / 7	GLN A 728 VAL A 727 ALA A 707 THR A 706	None	0.95A	6cduH-1k25A: 0.0 6cduI-1k25A: undetectable	6cduH-1k25A: 18.31 6cduI-1k25A: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLO_A_GBQA1501_1 (SUBSTANCE-P RECEPTOR,GLGA GLYCOGEN SYNTHASE,SUBSTANCE-P RECEPTOR)	1k25	LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X (Streptococcus pneumoniae)	5 / 9	ILE A 741 ILE A 738 GLU A 719 VAL A 732 ILE A 696	None	1.30A	6hloA-1k25A: undetectable	6hloA-1k25A: 21.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HRK_A_CHDA1502_0","FERROCHELATASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 714;PRO A 646;VAL A 663;GLY A 664","None","0.94A","1hrkA-1k25A:undetectable","1hrkA-1k25A:19.05"],["1HRK_B_CHDB2502_0","FERROCHELATASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 714;PRO A 646;VAL A 663;GLY A 664","None","0.92A","1hrkB-1k25A:undetectable","1hrkB-1k25A:19.05"],["1ICT_D_T44D129_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.84A","1ictB-1k25A:undetectable","1ictB-1k25A:10.80"],["2A58_B_RBFB301_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"LEU A 223;ALA A  88;GLY A 199;SER A 217;GLU A 220","None","1.25A","2a58A-1k25A:undetectable;2a58B-1k25A:undetectable","2a58A-1k25A:14.31;2a58B-1k25A:14.31"],["2A58_C_RBFC302_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"LEU A 223;ALA A  88;GLY A 199;SER A 217;GLU A 220","None","1.25A","2a58B-1k25A:undetectable;2a58C-1k25A:undetectable","2a58B-1k25A:14.31;2a58C-1k25A:14.31"],["2A58_E_RBFE304_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"LEU A 223;ALA A  88;GLY A 199;SER A 217;GLU A 220","None","1.25A","2a58D-1k25A:undetectable;2a58E-1k25A:undetectable","2a58D-1k25A:14.31;2a58E-1k25A:14.31"],["2DM6_A_IMNA1401_1","NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE;NADP-DEPENDENT LEUKOTRIENE B4 12-HYDROXYDEHYDROGENASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"TYR A 262;ALA A 624;ILE A 480;PRO A 682;ILE A 657","None","1.34A","2dm6A-1k25A:undetectable;2dm6B-1k25A:undetectable","2dm6A-1k25A:19.21;2dm6B-1k25A:19.21"],["2G72_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"TYR A 586;LEU A 462;ILE A 468;VAL A 341;TYR A 333","None","1.19A","2g72B-1k25A:undetectable","2g72B-1k25A:16.86"],["2ROX_B_T44B128_1","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.89A","2roxB-1k25A:undetectable","2roxB-1k25A:10.80"],["3BJW_C_SVRC507_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"VAL A 423;GLN A 436;PHE A 419;ARG A 426","None","1.13A","3bjwF-1k25A:0.0","3bjwF-1k25A:9.63"],["3CFQ_B_DIFB1_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.86A","3cfqA-1k25A:undetectable;3cfqB-1k25A:undetectable","3cfqA-1k25A:10.36;3cfqB-1k25A:10.36"],["3D2T_A_1FLA502_1","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.83A","3d2tA-1k25A:undetectable","3d2tA-1k25A:10.80"],["3DDY_A_RBFA187_1","LUMAZINE PROTEIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A  85;SER A 267;ILE A 198;ALA A 194;THR A 305","None","1.24A","3ddyA-1k25A:0.0","3ddyA-1k25A:15.63"],["3FSU_A_C2FA995_0","5,10-METHYLENETETRAHYDROFOLATE REDUCTASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 264;LEU A 429;SER A 217;LEU A 328;THR A 459","None","1.25A","3fsuA-1k25A:undetectable","3fsuA-1k25A:17.65"],["3HCP_B_CHDB4_0","FERROCHELATASE, MITOCHONDRIAL","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",3,"GLY A 422;PRO A 438;LEU A 416","None","0.58A","3hcpB-1k25A:0.0","3hcpB-1k25A:18.90"],["3KU1_H_SAMH226_0","SAM-DEPENDENT METHYLTRANSFERASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"GLY A 453;VAL A 456;PRO A 335;ALA A 446;LEU A 413","None","0.96A","3ku1H-1k25A:undetectable","3ku1H-1k25A:15.51"],["3VYW_B_SAMB401_1","MNMC2","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"GLU A 316;ASP A 278;ASP A 313;GLU A 274","None","1.48A","3vywB-1k25A:0.0","3vywB-1k25A:19.10"],["4D7B_A_TCWA1126_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.81A","4d7bB-1k25A:0.0","4d7bB-1k25A:10.80"],["4D7B_B_TCWB1126_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.76A","4d7bA-1k25A:undetectable","4d7bA-1k25A:10.80"],["4DTZ_A_LDPA501_1","CYTOCHROME P450 BM3 VARIANT 8C8","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"PHE A 603;ALA A 572;LEU A 585;THR A 574","None","0.95A","4dtzA-1k25A:0.0","4dtzA-1k25A:21.55"],["4I89_A_1FLA201_1","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.81A","4i89A-1k25A:undetectable","4i89A-1k25A:12.81"],["4IKJ_B_SUZB201_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.89A","4ikjA-1k25A:undetectable;4ikjB-1k25A:undetectable","4ikjA-1k25A:10.80;4ikjB-1k25A:10.80"],["4IKK_A_SUZA201_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.90A","4ikkA-1k25A:undetectable;4ikkB-1k25A:undetectable","4ikkA-1k25A:10.80;4ikkB-1k25A:10.80"],["4IKK_B_SUZB201_1","TRANSTHYRETIN;TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.94A","4ikkA-1k25A:undetectable;4ikkB-1k25A:undetectable","4ikkA-1k25A:10.80;4ikkB-1k25A:10.80"],["4KMU_C_RFPC1401_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"GLN A 306;ASP A  81;LEU A 328;ILE A 301;ARG A  82","None","1.26A","4kmuC-1k25A:0.0","4kmuC-1k25A:20.44"],["4S0V_A_SUVA2001_1","HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 292;VAL A 294;GLN A 458;THR A 457;GLN A 460","None","1.49A","4s0vA-1k25A:undetectable","4s0vA-1k25A:21.98"],["4UBS_A_DIFA502_1","PENTALENIC ACID SYNTHASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 663;LEU A 746;LEU A 714;LEU A 718;ILE A 716","None","1.33A","4ubsA-1k25A:0.0","4ubsA-1k25A:19.09"],["4XDT_A_ACTA407_0","FAD:PROTEIN FMN TRANSFERASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",3,"ASP A  90;GLY A  77;ASP A 260","None","0.62A","4xdtA-1k25A:0.0","4xdtA-1k25A:19.10"],["4YGF_A_AZMA303_1","ALPHA-CARBONIC ANHYDRASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 546;VAL A 544;LEU A 608;THR A 605;ALA A 604","None","1.49A","4ygfA-1k25A:undetectable","4ygfA-1k25A:15.72"],["4YHA_B_MZMB303_1","ALPHA-CARBONIC ANHYDRASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 546;VAL A 544;LEU A 608;THR A 605;ALA A 604","None","1.48A","4yhaB-1k25A:undetectable","4yhaB-1k25A:15.72"],["5BOJ_A_4TXA201_1","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.82A","5bojA-1k25A:undetectable","5bojA-1k25A:10.80"],["5BOJ_B_4TXB201_1","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.78A","5bojB-1k25A:0.0","5bojB-1k25A:10.80"],["5CF9_B_NCAB302_0","RIBOSOME-INACTIVATING PROTEIN MOMORDIN I","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"ILE A 198;GLY A 218;ILE A  79;ALA A  88;ARG A 186","None","1.41A","5cf9B-1k25A:undetectable","5cf9B-1k25A:17.75"],["5G5G_A_ACTA1231_0","PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT;PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",3,"ARG A 733;THR A 411;ASP A 414","None","0.81A","5g5gA-1k25A:0.0;5g5gB-1k25A:0.0","5g5gA-1k25A:15.91;5g5gB-1k25A:18.81"],["5HES_A_032A401_1","MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",6,"GLY A 500;VAL A 503;ALA A 508;ILE A 348;THR A 511;ALA A 469","None","1.43A","5hesA-1k25A:undetectable","5hesA-1k25A:18.85"],["5HHJ_B_GLYB404_0","RETRON-TYPE REVERSE TRANSCRIPTASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"GLN A 452;ALA A 551;GLN A 552;THR A 550","None","1.46A","5hhjB-1k25A:0.0","5hhjB-1k25A:19.53"],["5L4I_A_6J3A201_0","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.80A","5l4iA-1k25A:undetectable","5l4iA-1k25A:10.80"],["5L4I_B_6J3B201_0","TRANSTHYRETIN","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"LEU A 585;ALA A 291;LEU A 293;THR A 305","None","0.77A","5l4iB-1k25A:0.0","5l4iB-1k25A:10.80"],["5OJ0_A_9WTA801_0","PENICILLIN-BINDING PROTEIN 2X","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"ASN A 397;SER A 548;GLY A 549;THR A 550;GLN A 552","None","1.18A","5oj0A-1k25A:48.9","5oj0A-1k25A:88.61"],["5OJ0_A_9WTA801_0","PENICILLIN-BINDING PROTEIN 2X","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"GLN A 447;GLN A 452;SER A 548;GLY A 549;THR A 550","None","0.50A","5oj0A-1k25A:48.9","5oj0A-1k25A:88.61"],["5TT3_B_EZLB303_1","ALPHA-CARBONIC ANHYDRASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 546;VAL A 544;LEU A 608;THR A 605;ALA A 604","None","1.47A","5tt3B-1k25A:undetectable","5tt3B-1k25A:15.72"],["5TT3_E_EZLE303_1","ALPHA-CARBONIC ANHYDRASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 546;VAL A 544;LEU A 608;THR A 605;ALA A 604","None","1.50A","5tt3E-1k25A:undetectable","5tt3E-1k25A:15.72"],["5TT3_G_EZLG303_1","ALPHA-CARBONIC ANHYDRASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"VAL A 546;VAL A 544;LEU A 608;THR A 605;ALA A 604","None","1.50A","5tt3G-1k25A:undetectable","5tt3G-1k25A:15.72"],["5VCY_A_DB8A401_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"VAL A 503;LEU A 344;ASN A 470;ASP A 471","None","1.16A","5vcyA-1k25A:undetectable","5vcyA-1k25A:19.49"],["6B5Y_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 459;ILE A 301;TYR A 586;THR A 588;THR A 290","None","1.40A","6b5yA-1k25A:13.1;6b5yB-1k25A:6.9","6b5yA-1k25A:9.69;6b5yB-1k25A:9.69"],["6B68_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 459;ILE A 301;TYR A 586;THR A 588;THR A 290","None","1.41A","6b68A-1k25A:13.2;6b68B-1k25A:13.1","6b68A-1k25A:9.69;6b68B-1k25A:9.69"],["6B6A_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 459;ILE A 301;TYR A 586;THR A 588;THR A 290","None","1.41A","6b6aA-1k25A:13.1;6b6aB-1k25A:13.2","6b6aA-1k25A:9.69;6b6aB-1k25A:9.69"],["6B6A_C_9F2C302_1","BETA-LACTAMASE;BETA-LACTAMASE","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"THR A 459;ILE A 301;TYR A 586;THR A 588;THR A 290","None","1.43A","6b6aC-1k25A:13.1;6b6aD-1k25A:13.1","6b6aC-1k25A:9.69;6b6aD-1k25A:9.69"],["6CDU_F_EY4F500_0","CHIMERIC ALPHA1GABAA RECEPTOR","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"ALA A 707;THR A 706;GLN A 728;VAL A 727","None","0.94A","6cduF-1k25A:undetectable;6cduJ-1k25A:undetectable","6cduF-1k25A:18.31;6cduJ-1k25A:18.31"],["6CDU_H_EY4H500_0","CHIMERIC ALPHA1GABAA RECEPTOR","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",4,"GLN A 728;VAL A 727;ALA A 707;THR A 706","None","0.95A","6cduH-1k25A:0.0;6cduI-1k25A:undetectable","6cduH-1k25A:18.31;6cduI-1k25A:18.31"],["6HLO_A_GBQA1501_1","SUBSTANCE-P RECEPTOR,GLGA GLYCOGEN SYNTHASE,SUBSTANCE-P RECEPTOR","1k25","LOW-AFFINITY PENICILLIN-BINDING PROTEIN 2X","Streptococcus pneumoniae",5,"ILE A 741;ILE A 738;GLU A 719;VAL A 732;ILE A 696","None","1.30A","6hloA-1k25A:undetectable","6hloA-1k25A:21.23"]]