SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k3e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1k3e CEST
(Escherichia
coli) 		5 / 12 ALA A  72
LEU A  84
LEU A 123
LEU A 134
PHE A  65
 None
 1.15A 3fl9G-1k3eA:
undetectable		 3fl9G-1k3eA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 1k3e CEST
(Escherichia
coli) 		3 / 3 SER A 146
GLU A   6
GLU A  14
 None
 0.79A 4ymgB-1k3eA:
undetectable		 4ymgB-1k3eA:
20.08