SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k3g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 9 LEU A  61
ILE A  64
VAL A  27
CYH A  32
ALA A  76
 None
HEC  A  93 (-3.6A)
None
HEC  A  93 (-1.8A)
HEC  A  93 ( 3.6A)
 1.00A 1e7aA-1k3gA:
undetectable		 1e7aA-1k3gA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 12 ILE A  33
MET A  71
VAL A  84
ALA A  76
ILE A  64
 None
HEC  A  93 (-2.4A)
HEC  A  93 (-4.2A)
HEC  A  93 ( 3.6A)
HEC  A  93 (-3.6A)
 0.96A 1epbA-1k3gA:
undetectable		 1epbA-1k3gA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 9 LEU A  61
ASP A  62
LEU A  65
ILE A  75
ILE A  48
 None
None
None
HEC  A  93 (-3.5A)
HEC  A  93 (-3.8A)
 1.46A 1hzeA-1k3gA:
undetectable
1hzeB-1k3gA:
undetectable		 1hzeA-1k3gA:
21.21
1hzeB-1k3gA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 9 ILE A  48
LEU A  61
ASP A  62
LEU A  65
ILE A  75
 HEC  A  93 (-3.8A)
None
None
None
HEC  A  93 (-3.5A)
 1.46A 1hzeA-1k3gA:
undetectable
1hzeB-1k3gA:
undetectable		 1hzeA-1k3gA:
21.21
1hzeB-1k3gA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 12 GLU A  57
ILE A  48
LEU A  40
GLY A  52
ILE A  60
 None
HEC  A  93 (-3.8A)
None
None
HEC  A  93 (-3.5A)
 1.29A 2e7fA-1k3gA:
undetectable		 2e7fA-1k3gA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 12 GLU A  57
ILE A  48
LEU A  40
GLY A  52
ILE A  60
 None
HEC  A  93 (-3.8A)
None
None
HEC  A  93 (-3.5A)
 1.26A 2e7fB-1k3gA:
undetectable		 2e7fB-1k3gA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 12 GLU A  57
ILE A  48
LEU A  40
GLY A  52
ILE A  60
 None
HEC  A  93 (-3.8A)
None
None
HEC  A  93 (-3.5A)
 1.29A 2ogyA-1k3gA:
undetectable		 2ogyA-1k3gA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1k3g CYTOCHROME C-553
(Sporosarcina
pasteurii) 		5 / 12 GLU A  57
ILE A  48
LEU A  40
GLY A  52
ILE A  60
 None
HEC  A  93 (-3.8A)
None
None
HEC  A  93 (-3.5A)
 1.29A 2ogyB-1k3gA:
undetectable		 2ogyB-1k3gA:
15.00