SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X1L_A_ADNA601_1 (METHIONYL-TRNA SYNTHETASE)	1k3k	FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG (Human gammaherpesvirus 8)	5 / 11	ALA A 119 ALA A 87 GLY A 132 ILE A 13 TRP A 134	None	1.13A	2x1lA-1k3kA: undetectable	2x1lA-1k3kA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X1L_C_ADNC601_1 (METHIONYL-TRNA SYNTHETASE)	1k3k	FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG (Human gammaherpesvirus 8)	5 / 11	ALA A 119 ALA A 87 GLY A 132 ILE A 13 TRP A 134	None	1.07A	2x1lC-1k3kA: undetectable	2x1lC-1k3kA: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU9_A_478A401_1 (PROTEASE)	1k3k	FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG (Human gammaherpesvirus 8)	4 / 8	ALA A 111 ASP A 109 GLY A 15 ILE A 16	None	0.74A	3nu9A-1k3kA: undetectable	3nu9A-1k3kA: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BKL_G_EU7G101_0 (MATRIX PROTEIN 2)	1k3k	FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG (Human gammaherpesvirus 8)	5 / 9	ALA A 111 ALA A 98 GLY A 94 ALA A 19 GLY A 21	None	1.16A	6bklE-1k3kA: undetectable 6bklF-1k3kA: undetectable 6bklG-1k3kA: undetectable 6bklH-1k3kA: undetectable	6bklE-1k3kA: 10.53 6bklF-1k3kA: 10.53 6bklG-1k3kA: 10.53 6bklH-1k3kA: 10.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X1L_A_ADNA601_1","METHIONYL-TRNA SYNTHETASE","1k3k","FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG","Human gammaherpesvirus 8",5,"ALA A 119;ALA A  87;GLY A 132;ILE A  13;TRP A 134","None","1.13A","2x1lA-1k3kA:undetectable","2x1lA-1k3kA:15.84"],["2X1L_C_ADNC601_1","METHIONYL-TRNA SYNTHETASE","1k3k","FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG","Human gammaherpesvirus 8",5,"ALA A 119;ALA A  87;GLY A 132;ILE A  13;TRP A 134","None","1.07A","2x1lC-1k3kA:undetectable","2x1lC-1k3kA:15.84"],["3NU9_A_478A401_1","PROTEASE","1k3k","FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG","Human gammaherpesvirus 8",4,"ALA A 111;ASP A 109;GLY A  15;ILE A  16","None","0.74A","3nu9A-1k3kA:undetectable","3nu9A-1k3kA:21.09"],["6BKL_G_EU7G101_0","MATRIX PROTEIN 2","1k3k","FUNCTIONAL ANTI-APOPTOTIC FACTOR VBCL-2 HOMOLOG","Human gammaherpesvirus 8",5,"ALA A 111;ALA A  98;GLY A  94;ALA A  19;GLY A  21","None","1.16A","6bklE-1k3kA:undetectable;6bklF-1k3kA:undetectable;6bklG-1k3kA:undetectable;6bklH-1k3kA:undetectable","6bklE-1k3kA:10.53;6bklF-1k3kA:10.53;6bklG-1k3kA:10.53;6bklH-1k3kA:10.53"]]