SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		4 / 8 SER A  90
ALA A 101
ILE A 234
ASN A  87
 None
 1.13A 1pnlA-1k3vA:
0.0
1pnlB-1k3vA:
0.0		 1pnlA-1k3vA:
17.06
1pnlB-1k3vA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		4 / 5 GLN A 513
TRP A 109
GLU A  78
LEU A 255
 None
 1.48A 1ulvA-1k3vA:
undetectable		 1ulvA-1k3vA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		3 / 3 GLY A 300
GLU A 299
ASP A 301
 None
 0.70A 2b25B-1k3vA:
undetectable		 2b25B-1k3vA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 8 ARG A 209
LEU A 111
ASP A 113
ALA A 114
GLY A 196
 None
 1.45A 2o4nB-1k3vA:
undetectable		 2o4nB-1k3vA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 9 LEU A 274
ALA A 482
ASP A 467
VAL A 485
VAL A 357
 None
 0.95A 3oxvC-1k3vA:
undetectable		 3oxvC-1k3vA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 10 LEU A 274
ALA A 482
ASP A 467
VAL A 485
VAL A 357
 None
 1.02A 3oxwA-1k3vA:
undetectable		 3oxwA-1k3vA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		3 / 3 GLN A 127
THR A 547
THR A 548
 None
 0.62A 4fu9A-1k3vA:
0.0		 4fu9A-1k3vA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		3 / 3 GLN A 127
THR A 547
THR A 548
 None
 0.64A 4fufA-1k3vA:
0.0		 4fufA-1k3vA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		4 / 7 MET A 133
PRO A 458
SER A 571
TRP A 117
 None
 1.49A 4kmmA-1k3vA:
undetectable		 4kmmA-1k3vA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUF_A_ACTA605_0
(SERUM ALBUMIN)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		4 / 4 ALA A 116
HIS A 381
PHE A 197
LEU A 195
 None
 1.50A 4lufA-1k3vA:
undetectable		 4lufA-1k3vA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		4 / 6 LEU A  72
ASN A  73
LEU A 150
ILE A 153
 None
 1.16A 4okxA-1k3vA:
undetectable		 4okxA-1k3vA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 12 LEU A 274
PRO A 483
THR A 456
PHE A 396
GLY A 371
 None
 1.38A 4q15A-1k3vA:
undetectable		 4q15A-1k3vA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 12 LEU A 274
PRO A 483
THR A 456
PHE A 396
GLY A 371
 None
 1.32A 4q15B-1k3vA:
undetectable		 4q15B-1k3vA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 12 LEU A  86
ALA A 101
LEU A 218
ASN A 217
ILE A 230
 None
 0.92A 4x1yB-1k3vA:
undetectable		 4x1yB-1k3vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 12 LEU A  86
ALA A 101
LEU A 218
ASN A 217
ILE A 230
 None
 1.04A 4x20B-1k3vA:
0.0		 4x20B-1k3vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		3 / 3 THR A 194
HIS A 381
ASN A 462
 None
 0.98A 5n4tA-1k3vA:
0.0		 5n4tA-1k3vA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H1L_A_FJQA501_0
(BIFUNCTIONAL
CYTOCHROME
P450/NADPH--P450
REDUCTASE)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 10 ALA A 176
LEU A 177
VAL A 251
THR A 186
LEU A 183
 None
 1.44A 6h1lA-1k3vA:
undetectable		 6h1lA-1k3vA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 1k3v CAPSID PROTEIN VP2
(Ungulate
protoparvovirus
1) 		5 / 10 PRO A 369
THR A 339
ASN A 338
LEU A 444
MET A 441
 None
 1.13A 6hupD-1k3vA:
undetectable
6hupE-1k3vA:
0.0		 6hupD-1k3vA:
9.79
6hupE-1k3vA:
8.73