SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k3z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1k3z TRANSCRIPTION FACTOR
P65
(Mus
musculus) 		4 / 6 GLU A 225
ARG A 236
ARG A 274
ARG A 273
 None
 1.16A 5l6eA-1k3zA:
undetectable
5l6eB-1k3zA:
undetectable		 5l6eA-1k3zA:
20.69
5l6eB-1k3zA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 1k3z TRANSCRIPTION FACTOR
P65
(Mus
musculus) 		3 / 3 ARG A 304
ARG A 297
ARG A 302
 None
 0.99A 5vcgA-1k3zA:
undetectable		 5vcgA-1k3zA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1k3z TRANSCRIPTION FACTOR
P65
(Mus
musculus) 		4 / 7 ILE A 196
VAL A 226
ILE A 212
THR A 254
 None
 0.96A 6cduF-1k3zA:
1.9
6cduG-1k3zA:
2.5		 6cduF-1k3zA:
16.77
6cduG-1k3zA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1k3z TRANSCRIPTION FACTOR
P65
(Mus
musculus) 		4 / 8 ILE A 196
VAL A 226
ILE A 212
THR A 254
 None
 0.87A 6cduG-1k3zA:
2.5
6cduH-1k3zA:
2.3		 6cduG-1k3zA:
16.77
6cduH-1k3zA:
16.77