SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k44'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  90
ALA A  89
VAL A   7
ILE A  26
THR A   5
 None
 0.83A 1c6yB-1k44A:
undetectable		 1c6yB-1k44A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		4 / 8 SER A 119
THR A   5
ALA A  73
ALA A  74
 None
 1.03A 3ax9B-1k44A:
undetectable		 3ax9B-1k44A:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 116
ILE A  26
ILE A   9
LEU A   8
 None
 0.80A 3hegA-1k44A:
undetectable		 3hegA-1k44A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		4 / 8 SER A 119
THR A   5
ALA A  73
ALA A  74
 None
 0.99A 3ns1L-1k44A:
0.5		 3ns1L-1k44A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		4 / 6 GLY A 105
ARG A  16
GLU A  21
ARG A  25
 None
 1.00A 4bqfA-1k44A:
undetectable		 4bqfA-1k44A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1k44 NUCLEOSIDE
DIPHOSPHATE KINASE
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  22
GLY A  13
ILE A  66
VAL A  72
 None
 0.83A 4r21A-1k44A:
undetectable		 4r21A-1k44A:
14.58