SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		4 / 6 MET A  75
LEU A 102
GLU A  73
LEU A  49
 None
 0.99A 1etb1-1k4nA:
0.0		 1etb1-1k4nA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		3 / 3 ASP A 170
LEU A  28
LEU A  31
 None
 0.71A 1ikeA-1k4nA:
0.0		 1ikeA-1k4nA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		3 / 3 ASP A 170
LEU A  28
LEU A  31
 None
 0.68A 1np1B-1k4nA:
0.0		 1np1B-1k4nA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		4 / 7 ARG A  50
SER A  48
ARG A  79
GLU A 119
 None
 1.32A 2c8aA-1k4nA:
undetectable		 2c8aA-1k4nA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		4 / 6 ARG A  50
SER A  48
ARG A  79
GLU A 119
 None
 1.31A 2c8aC-1k4nA:
undetectable		 2c8aC-1k4nA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		3 / 3 TRP A 115
GLN A   9
TRP A  95
 None
 1.31A 2vqyA-1k4nA:
undetectable		 2vqyA-1k4nA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		4 / 7 VAL A  90
ILE A  17
HIS A  46
LEU A  83
 None
 1.11A 4xo7B-1k4nA:
undetectable		 4xo7B-1k4nA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_2
(TUBULIN BETA CHAIN)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		5 / 12 ALA A  93
LEU A  28
ILE A 120
ALA A  44
ILE A 175
 None
 1.28A 5eypB-1k4nA:
undetectable		 5eypB-1k4nA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 1k4n PROTEIN EC4020
(Escherichia
coli) 		3 / 3 PRO A 103
ARG A  79
GLU A 101
 None
 0.98A 5j6hA-1k4nA:
undetectable		 5j6hA-1k4nA:
21.05