SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 1k4z ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 SER A1434
LEU A1432
ILE A1393
ILE A1413
 None
 0.86A 1sbrA-1k4zA:
0.0		 1sbrA-1k4zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1k4z ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 SER A1484
SER A1427
GLN A1408
ASP A1464
 None
 1.50A 5fhrB-1k4zA:
undetectable		 5fhrB-1k4zA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 1k4z ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 SER A1484
THR A1485
ALA A1486
PHE A1447
VAL A1441
 None
 1.47A 6drxA-1k4zA:
undetectable		 6drxA-1k4zA:
17.93