SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 8 ALA B 255
GLY B 392
ILE B 395
PHE B 367
 None
 0.79A 1d4sB-1k5sB:
undetectable		 1d4sB-1k5sB:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 6 GLY B 509
ALA B 465
TYR B 521
GLU B 468
 None
 0.98A 1dmaB-1k5sB:
undetectable		 1dmaB-1k5sB:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 7 SER B   1
SER B  67
ALA B  69
ILE B 177
 GRO  B 601 (-2.3A)
GRO  B 601 (-4.6A)
GRO  B 601 (-3.0A)
GRO  B 601 ( 4.4A)
 0.22A 1fxhA-1k5sB:
0.0
1fxhB-1k5sB:
61.7		 1fxhA-1k5sB:
16.67
1fxhB-1k5sB:
99.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 8 SER B   1
SER B  67
ALA B  69
PHE B  71
ILE B 177
 GRO  B 601 (-2.3A)
GRO  B 601 (-4.6A)
GRO  B 601 (-3.0A)
None
GRO  B 601 ( 4.4A)
 0.43A 1gm7A-1k5sB:
0.0
1gm7B-1k5sB:
60.5		 1gm7A-1k5sB:
16.67
1gm7B-1k5sB:
99.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		6 / 7 SER B   1
PRO B  22
ALA B  24
TYR B  31
SER B  67
ALA B  69
 GRO  B 601 (-2.3A)
None
GRO  B 601 ( 4.0A)
None
GRO  B 601 (-4.6A)
GRO  B 601 (-3.0A)
 0.35A 1k5qA-1k5sB:
0.0
1k5qB-1k5sB:
61.9		 1k5qA-1k5sB:
15.99
1k5qB-1k5sB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 8 SER B   1
SER B  67
ALA B  69
ILE B 177
ASN B 241
 GRO  B 601 (-2.3A)
GRO  B 601 (-4.6A)
GRO  B 601 (-3.0A)
GRO  B 601 ( 4.4A)
GRO  B 601 (-3.7A)
 0.35A 1pnlA-1k5sB:
0.0
1pnlB-1k5sB:
59.2		 1pnlA-1k5sB:
16.67
1pnlB-1k5sB:
99.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.89A 1t7iA-1k5sB:
undetectable		 1t7iA-1k5sB:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 1v54A-1k5sB:
2.8
1v54B-1k5sB:
0.0
1v54T-1k5sB:
0.0		 1v54A-1k5sB:
20.53
1v54B-1k5sB:
17.45
1v54T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.12A 1v54G-1k5sB:
0.0
1v54N-1k5sB:
0.1
1v54O-1k5sB:
0.0		 1v54G-1k5sB:
12.50
1v54N-1k5sB:
20.53
1v54O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 1v55A-1k5sB:
0.1
1v55B-1k5sB:
0.0
1v55T-1k5sB:
0.0		 1v55A-1k5sB:
20.53
1v55B-1k5sB:
17.45
1v55T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.13A 1v55G-1k5sB:
0.0
1v55N-1k5sB:
0.2
1v55O-1k5sB:
0.0		 1v55G-1k5sB:
12.50
1v55N-1k5sB:
20.53
1v55O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 4 LEU B 296
PRO B 448
ILE B 346
LEU B 347
 None
 1.17A 1ya4C-1k5sB:
0.2		 1ya4C-1k5sB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 2dyrA-1k5sB:
0.8
2dyrB-1k5sB:
0.0
2dyrT-1k5sB:
0.0		 2dyrA-1k5sB:
20.53
2dyrB-1k5sB:
17.45
2dyrT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 2dyrG-1k5sB:
0.0
2dyrN-1k5sB:
0.0
2dyrO-1k5sB:
0.0		 2dyrG-1k5sB:
12.50
2dyrN-1k5sB:
20.53
2dyrO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_B_CHDB304_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 2dysA-1k5sB:
0.8
2dysB-1k5sB:
0.0
2dysT-1k5sB:
0.0		 2dysA-1k5sB:
20.53
2dysB-1k5sB:
17.45
2dysT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_O_CHDO302_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 9 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 2dysG-1k5sB:
0.0
2dysN-1k5sB:
2.9
2dysO-1k5sB:
0.0		 2dysG-1k5sB:
12.50
2dysN-1k5sB:
20.53
2dysO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 2eijA-1k5sB:
0.0
2eijB-1k5sB:
0.0
2eijT-1k5sB:
0.0		 2eijA-1k5sB:
20.53
2eijB-1k5sB:
17.45
2eijT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 2eijG-1k5sB:
0.0
2eijN-1k5sB:
0.1
2eijO-1k5sB:
0.0		 2eijG-1k5sB:
12.50
2eijN-1k5sB:
20.53
2eijO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 2eikA-1k5sB:
0.0
2eikB-1k5sB:
0.0
2eikT-1k5sB:
0.0		 2eikA-1k5sB:
20.53
2eikB-1k5sB:
17.45
2eikT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 2eikG-1k5sB:
0.0
2eikN-1k5sB:
0.0
2eikO-1k5sB:
0.0		 2eikG-1k5sB:
12.50
2eikN-1k5sB:
20.53
2eikO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 2eilA-1k5sB:
0.2
2eilB-1k5sB:
0.0
2eilT-1k5sB:
0.0		 2eilA-1k5sB:
20.53
2eilB-1k5sB:
17.45
2eilT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 2eilG-1k5sB:
0.0
2eilN-1k5sB:
0.2
2eilO-1k5sB:
0.0		 2eilG-1k5sB:
12.50
2eilN-1k5sB:
20.53
2eilO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.23A 2eimA-1k5sB:
1.0
2eimB-1k5sB:
0.0
2eimT-1k5sB:
0.0		 2eimA-1k5sB:
20.53
2eimB-1k5sB:
17.45
2eimT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CHDN1604_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.16A 2eimG-1k5sB:
0.0
2eimN-1k5sB:
0.2
2eimO-1k5sB:
0.0		 2eimG-1k5sB:
12.50
2eimN-1k5sB:
20.53
2eimO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.23A 2einA-1k5sB:
0.0
2einB-1k5sB:
0.0
2einT-1k5sB:
0.0		 2einA-1k5sB:
20.53
2einB-1k5sB:
17.45
2einT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_B_AZZB1211_1
(DEOXYNUCLEOSIDE
KINASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 GLU B 482
LEU B 536
GLN B 524
VAL B 502
ALA B 504
 None
 1.47A 2jj8B-1k5sB:
undetectable		 2jj8B-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.83A 2nnkB-1k5sB:
undetectable		 2nnkB-1k5sB:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		3 / 3 SER B 508
TYR B 521
HIS B 520
 None
 0.77A 2r2vD-1k5sB:
0.0		 2r2vD-1k5sB:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		3 / 3 TRP B 154
GLN B 169
TRP B 143
 None
 1.32A 2vqyA-1k5sB:
0.0		 2vqyA-1k5sB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_G_CHDG1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.16A 2y69G-1k5sB:
0.0
2y69N-1k5sB:
0.0
2y69O-1k5sB:
0.0		 2y69G-1k5sB:
10.62
2y69N-1k5sB:
20.53
2y69O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_T_CHDT1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 2y69A-1k5sB:
0.0
2y69B-1k5sB:
0.0
2y69T-1k5sB:
0.0		 2y69A-1k5sB:
20.53
2y69B-1k5sB:
17.45
2y69T-1k5sB:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 7 ASP B 280
ARG B 533
VAL B  19
ILE B  17
 None
 0.92A 2yfbA-1k5sB:
0.5		 2yfbA-1k5sB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 6 ASP B 280
ARG B 533
VAL B  19
ILE B  17
 None
 0.95A 2yfbB-1k5sB:
undetectable		 2yfbB-1k5sB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.23A 2zxwA-1k5sB:
0.8
2zxwB-1k5sB:
0.0
2zxwT-1k5sB:
0.0		 2zxwA-1k5sB:
20.53
2zxwB-1k5sB:
17.45
2zxwT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.16A 2zxwG-1k5sB:
0.0
2zxwN-1k5sB:
0.0
2zxwO-1k5sB:
0.0		 2zxwG-1k5sB:
12.50
2zxwN-1k5sB:
20.53
2zxwO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 3abkA-1k5sB:
0.7
3abkB-1k5sB:
0.0
3abkT-1k5sB:
0.0		 3abkA-1k5sB:
20.53
3abkB-1k5sB:
17.45
3abkT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 3abkG-1k5sB:
0.0
3abkN-1k5sB:
0.2
3abkO-1k5sB:
0.0		 3abkG-1k5sB:
12.50
3abkN-1k5sB:
20.53
3abkO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.21A 3ablA-1k5sB:
0.3
3ablB-1k5sB:
0.0
3ablT-1k5sB:
0.0		 3ablA-1k5sB:
20.53
3ablB-1k5sB:
17.45
3ablT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 3ablG-1k5sB:
0.0
3ablN-1k5sB:
0.2
3ablO-1k5sB:
0.0		 3ablG-1k5sB:
12.50
3ablN-1k5sB:
20.53
3ablO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 3abmA-1k5sB:
0.2
3abmB-1k5sB:
0.0
3abmT-1k5sB:
0.0		 3abmA-1k5sB:
20.53
3abmB-1k5sB:
17.45
3abmT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 3abmG-1k5sB:
0.0
3abmN-1k5sB:
0.7
3abmO-1k5sB:
0.0		 3abmG-1k5sB:
12.50
3abmN-1k5sB:
20.53
3abmO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 6 TYR B  52
PHE B  50
PHE B 459
PHE B 460
 None
 1.36A 3af3A-1k5sB:
0.0		 3af3A-1k5sB:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 3ag1A-1k5sB:
0.9
3ag1B-1k5sB:
0.0
3ag1T-1k5sB:
0.0		 3ag1A-1k5sB:
20.53
3ag1B-1k5sB:
17.45
3ag1T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.20A 3ag1G-1k5sB:
0.0
3ag1N-1k5sB:
0.0
3ag1O-1k5sB:
0.0		 3ag1G-1k5sB:
12.50
3ag1N-1k5sB:
20.53
3ag1O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 3ag2A-1k5sB:
0.0
3ag2B-1k5sB:
0.0
3ag2T-1k5sB:
0.0		 3ag2A-1k5sB:
20.53
3ag2B-1k5sB:
17.45
3ag2T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_G_CHDG86_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.14A 3ag2G-1k5sB:
0.0
3ag2N-1k5sB:
0.0
3ag2O-1k5sB:
0.0		 3ag2G-1k5sB:
12.50
3ag2N-1k5sB:
20.53
3ag2O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.14A 3ag3A-1k5sB:
0.1
3ag3B-1k5sB:
0.0
3ag3T-1k5sB:
0.0		 3ag3A-1k5sB:
20.53
3ag3B-1k5sB:
17.45
3ag3T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.18A 3ag3G-1k5sB:
0.0
3ag3N-1k5sB:
2.7
3ag3O-1k5sB:
0.0		 3ag3G-1k5sB:
12.50
3ag3N-1k5sB:
20.53
3ag3O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 3ag4A-1k5sB:
0.0
3ag4B-1k5sB:
0.0
3ag4T-1k5sB:
0.0		 3ag4A-1k5sB:
20.53
3ag4B-1k5sB:
17.45
3ag4T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.20A 3ag4G-1k5sB:
0.0
3ag4N-1k5sB:
0.7
3ag4O-1k5sB:
0.0		 3ag4G-1k5sB:
12.50
3ag4N-1k5sB:
20.53
3ag4O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 3asnA-1k5sB:
0.8
3asnB-1k5sB:
0.0
3asnT-1k5sB:
0.0		 3asnA-1k5sB:
20.53
3asnB-1k5sB:
17.45
3asnT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.13A 3asnG-1k5sB:
0.0
3asnN-1k5sB:
2.7
3asnO-1k5sB:
0.0		 3asnG-1k5sB:
12.50
3asnN-1k5sB:
20.53
3asnO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 3asoA-1k5sB:
2.8
3asoB-1k5sB:
0.0
3asoT-1k5sB:
0.0		 3asoA-1k5sB:
20.53
3asoB-1k5sB:
17.45
3asoT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.13A 3asoG-1k5sB:
0.0
3asoN-1k5sB:
0.1
3asoO-1k5sB:
0.0		 3asoG-1k5sB:
12.50
3asoN-1k5sB:
20.53
3asoO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.89A 3bvbB-1k5sB:
undetectable		 3bvbB-1k5sB:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		6 / 12 ASP B 484
VAL B 503
GLY B 480
THR B  32
PRO B  49
THR B  48
 None
 1.46A 3el5B-1k5sB:
undetectable		 3el5B-1k5sB:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 7 TYR B 230
VAL B   5
ASN B 185
GLY B 186
 None
 1.15A 3kmoB-1k5sB:
undetectable		 3kmoB-1k5sB:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.92A 3lzvA-1k5sB:
undetectable		 3lzvA-1k5sB:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.91A 3oy4B-1k5sB:
undetectable		 3oy4B-1k5sB:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 9 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.85A 3u7sA-1k5sB:
undetectable		 3u7sA-1k5sB:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.17A 3wg7A-1k5sB:
0.0
3wg7B-1k5sB:
0.0
3wg7T-1k5sB:
0.0		 3wg7A-1k5sB:
20.53
3wg7B-1k5sB:
17.45
3wg7T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 3wg7G-1k5sB:
0.0
3wg7N-1k5sB:
2.4
3wg7O-1k5sB:
0.0		 3wg7G-1k5sB:
12.50
3wg7N-1k5sB:
20.53
3wg7O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 3x2qA-1k5sB:
0.0
3x2qB-1k5sB:
0.0
3x2qT-1k5sB:
0.0		 3x2qA-1k5sB:
20.53
3x2qB-1k5sB:
17.45
3x2qT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.18A 3x2qG-1k5sB:
0.0
3x2qN-1k5sB:
0.9
3x2qO-1k5sB:
0.0		 3x2qG-1k5sB:
12.50
3x2qN-1k5sB:
20.53
3x2qO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 GLY B  46
GLY B  36
ASP B 501
GLY B  66
PRO B  49
 None
 1.11A 4blvA-1k5sB:
undetectable		 4blvA-1k5sB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.91A 4dqeB-1k5sB:
undetectable		 4dqeB-1k5sB:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.90A 4dqfB-1k5sB:
undetectable		 4dqfB-1k5sB:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.94A 4dqhB-1k5sB:
undetectable		 4dqhB-1k5sB:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		3 / 3 GLY B 439
SER B 435
TRP B 431
 None
 0.95A 4e7cD-1k5sB:
0.0		 4e7cD-1k5sB:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		4 / 6 ARG B 479
GLY B  21
ASN B  47
GLU B 482
 None
 1.24A 4g0vB-1k5sB:
undetectable		 4g0vB-1k5sB:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.83A 4njtB-1k5sB:
undetectable		 4njtB-1k5sB:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 9 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.91A 4q1wA-1k5sB:
undetectable		 4q1wA-1k5sB:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.91A 4q1xA-1k5sB:
undetectable		 4q1xA-1k5sB:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.90A 4q1yA-1k5sB:
undetectable		 4q1yA-1k5sB:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 TRP B  65
GLY B  66
GLY B  58
ILE B  35
ASP B 484
 None
 1.15A 4rtsA-1k5sB:
undetectable		 4rtsA-1k5sB:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 5b1aA-1k5sB:
0.8
5b1aB-1k5sB:
0.0
5b1aT-1k5sB:
0.0		 5b1aA-1k5sB:
20.53
5b1aB-1k5sB:
17.45
5b1aT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 5b1aG-1k5sB:
0.0
5b1aN-1k5sB:
0.8
5b1aO-1k5sB:
0.0		 5b1aG-1k5sB:
12.50
5b1aN-1k5sB:
20.53
5b1aO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 5b1bA-1k5sB:
0.1
5b1bB-1k5sB:
0.0
5b1bT-1k5sB:
0.0		 5b1bA-1k5sB:
20.53
5b1bB-1k5sB:
17.45
5b1bT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 5b1bG-1k5sB:
0.0
5b1bN-1k5sB:
0.0
5b1bO-1k5sB:
0.0		 5b1bG-1k5sB:
12.50
5b1bN-1k5sB:
20.53
5b1bO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 5b3sA-1k5sB:
2.8
5b3sB-1k5sB:
0.0
5b3sT-1k5sB:
0.0		 5b3sA-1k5sB:
20.53
5b3sB-1k5sB:
17.45
5b3sT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.14A 5b3sG-1k5sB:
0.0
5b3sN-1k5sB:
0.3
5b3sO-1k5sB:
0.0		 5b3sG-1k5sB:
12.50
5b3sN-1k5sB:
20.53
5b3sO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 VAL B 543
ASP B 542
HIS B  38
LEU B  37
LEU B  55
 None
 1.07A 5hnwB-1k5sB:
undetectable		 5hnwB-1k5sB:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 VAL B 543
ASP B 542
HIS B  38
LEU B  37
LEU B  55
 None
 1.08A 5hnxB-1k5sB:
undetectable		 5hnxB-1k5sB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 VAL B 543
ASP B 542
HIS B  38
LEU B  37
LEU B  55
 None
 1.06A 5hnyB-1k5sB:
undetectable		 5hnyB-1k5sB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.19A 5iy5G-1k5sB:
0.0
5iy5N-1k5sB:
0.0
5iy5O-1k5sB:
0.0		 5iy5G-1k5sB:
9.69
5iy5N-1k5sB:
20.53
5iy5O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.25A 5iy5A-1k5sB:
0.0
5iy5B-1k5sB:
0.0
5iy5T-1k5sB:
0.0		 5iy5A-1k5sB:
20.53
5iy5B-1k5sB:
17.45
5iy5T-1k5sB:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 ILE B 188
GLY B 189
ALA B 182
ILE B  17
ALA B  16
 None
 1.02A 5n0tB-1k5sB:
undetectable		 5n0tB-1k5sB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 ASN B 457
GLN B 380
THR B 481
GLY B 385
THR B 384
 None
 1.25A 5oj0A-1k5sB:
undetectable		 5oj0A-1k5sB:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 LEU B 538
GLY B  58
ASP B 484
GLY B  34
ILE B  35
 None
 0.88A 5t2zB-1k5sB:
undetectable		 5t2zB-1k5sB:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 6 LEU B 310
VAL B 320
THR B 324
LEU B 424
GLU B 432
 None
 1.43A 5tudD-1k5sB:
undetectable		 5tudD-1k5sB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		3 / 3 HIS B 546
SER B 535
ARG B 495
 None
 0.87A 5u63A-1k5sB:
undetectable		 5u63A-1k5sB:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 12 ASN B  20
GLY B  21
VAL B  44
GLY B  46
ASN B  47
 None
 1.05A 5vopA-1k5sB:
undetectable		 5vopA-1k5sB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.21A 5w97G-1k5sB:
0.0
5w97a-1k5sB:
0.1
5w97b-1k5sB:
0.0		 5w97G-1k5sB:
12.50
5w97a-1k5sB:
20.53
5w97b-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 5w97A-1k5sB:
0.1
5w97B-1k5sB:
0.0
5w97g-1k5sB:
0.0		 5w97A-1k5sB:
20.53
5w97B-1k5sB:
17.45
5w97g-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 5wauA-1k5sB:
0.1
5wauB-1k5sB:
0.0
5waug-1k5sB:
0.0		 5wauA-1k5sB:
20.53
5wauB-1k5sB:
17.45
5waug-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.22A 5wauG-1k5sB:
0.0
5waua-1k5sB:
0.0
5waub-1k5sB:
0.0		 5wauG-1k5sB:
12.50
5waua-1k5sB:
20.53
5waub-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.16A 5x19A-1k5sB:
1.6
5x19B-1k5sB:
0.0
5x19T-1k5sB:
0.0		 5x19A-1k5sB:
20.53
5x19B-1k5sB:
17.45
5x19T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.18A 5x19G-1k5sB:
0.0
5x19N-1k5sB:
0.8
5x19O-1k5sB:
0.0		 5x19G-1k5sB:
12.50
5x19N-1k5sB:
20.53
5x19O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.17A 5x1bA-1k5sB:
1.4
5x1bB-1k5sB:
0.0
5x1bT-1k5sB:
0.0		 5x1bA-1k5sB:
20.53
5x1bB-1k5sB:
17.45
5x1bT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.11A 5x1bG-1k5sB:
0.0
5x1bN-1k5sB:
0.0
5x1bO-1k5sB:
0.0		 5x1bG-1k5sB:
12.50
5x1bN-1k5sB:
20.53
5x1bO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.17A 5x1fA-1k5sB:
1.6
5x1fB-1k5sB:
0.0
5x1fT-1k5sB:
0.0		 5x1fA-1k5sB:
20.53
5x1fB-1k5sB:
17.45
5x1fT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.15A 5x1fG-1k5sB:
0.0
5x1fN-1k5sB:
0.3
5x1fO-1k5sB:
0.0		 5x1fG-1k5sB:
12.50
5x1fN-1k5sB:
20.53
5x1fO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.18A 5xdqA-1k5sB:
1.4
5xdqB-1k5sB:
0.0
5xdqT-1k5sB:
0.0		 5xdqA-1k5sB:
20.53
5xdqB-1k5sB:
17.45
5xdqT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.18A 5xdqG-1k5sB:
0.0
5xdqN-1k5sB:
0.8
5xdqO-1k5sB:
0.0		 5xdqG-1k5sB:
12.50
5xdqN-1k5sB:
20.53
5xdqO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.19A 5xdxA-1k5sB:
0.3
5xdxB-1k5sB:
0.0
5xdxT-1k5sB:
0.0		 5xdxA-1k5sB:
20.53
5xdxB-1k5sB:
17.45
5xdxT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_O_CHDO301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.19A 5xdxG-1k5sB:
0.0
5xdxN-1k5sB:
0.0
5xdxO-1k5sB:
0.0		 5xdxG-1k5sB:
12.50
5xdxN-1k5sB:
20.53
5xdxO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.22A 5z84A-1k5sB:
0.3
5z84B-1k5sB:
0.0
5z84T-1k5sB:
0.0		 5z84A-1k5sB:
20.53
5z84B-1k5sB:
17.45
5z84T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_G_CHDG101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.20A 5z84G-1k5sB:
0.0
5z84N-1k5sB:
0.8
5z84O-1k5sB:
0.0		 5z84G-1k5sB:
12.50
5z84N-1k5sB:
20.53
5z84O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.20A 5z85G-1k5sB:
0.0
5z85N-1k5sB:
0.1
5z85O-1k5sB:
0.0		 5z85G-1k5sB:
12.50
5z85N-1k5sB:
20.53
5z85O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_T_CHDT101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 5z85A-1k5sB:
0.2
5z85B-1k5sB:
0.0
5z85T-1k5sB:
0.0		 5z85A-1k5sB:
20.53
5z85B-1k5sB:
17.45
5z85T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 5z86A-1k5sB:
2.7
5z86B-1k5sB:
0.0
5z86T-1k5sB:
0.0		 5z86A-1k5sB:
20.53
5z86B-1k5sB:
17.45
5z86T-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.20A 5z86G-1k5sB:
0.0
5z86N-1k5sB:
0.9
5z86O-1k5sB:
0.0		 5z86G-1k5sB:
12.50
5z86N-1k5sB:
20.53
5z86O-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 5zcoA-1k5sB:
0.2
5zcoB-1k5sB:
0.0
5zcoT-1k5sB:
0.0		 5zcoA-1k5sB:
20.53
5zcoB-1k5sB:
17.45
5zcoT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 5zcoG-1k5sB:
0.0
5zcoN-1k5sB:
0.0
5zcoO-1k5sB:
0.0		 5zcoG-1k5sB:
12.50
5zcoN-1k5sB:
20.53
5zcoO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.20A 5zcpA-1k5sB:
2.6
5zcpB-1k5sB:
0.0
5zcpT-1k5sB:
0.0		 5zcpA-1k5sB:
20.53
5zcpB-1k5sB:
17.45
5zcpT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.19A 5zcpG-1k5sB:
0.0
5zcpN-1k5sB:
0.8
5zcpO-1k5sB:
0.0		 5zcpG-1k5sB:
12.50
5zcpN-1k5sB:
20.53
5zcpO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.17A 5zcqA-1k5sB:
0.9
5zcqB-1k5sB:
0.0
5zcqT-1k5sB:
0.0		 5zcqA-1k5sB:
20.53
5zcqB-1k5sB:
17.45
5zcqT-1k5sB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 10 PHE B 531
GLY B 532
MET B 485
GLU B 482
THR B 481
 None
 1.17A 5zcqG-1k5sB:
0.0
5zcqN-1k5sB:
0.8
5zcqO-1k5sB:
0.0		 5zcqG-1k5sB:
12.50
5zcqN-1k5sB:
20.53
5zcqO-1k5sB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		3 / 3 TRP B   4
ILE B 286
GLU B 482
 None
 0.81A 6hcxA-1k5sB:
undetectable		 6hcxA-1k5sB:
7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 1k5s PENICILLIN G ACYLASE
BETA SUBUNIT
(Escherichia
coli) 		5 / 11 MET B 485
GLU B 482
THR B 481
PHE B 531
GLY B 532
 None
 1.21A 6nknA-1k5sB:
0.0
6nknB-1k5sB:
0.0
6nknT-1k5sB:
0.0		 6nknA-1k5sB:
20.53
6nknB-1k5sB:
17.45
6nknT-1k5sB:
12.50