SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k61'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1k61 MATING-TYPE PROTEIN
ALPHA-2
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 184
PHE A 148
ASN A 154
TRP A 147
 None
 1.21A 1zzuA-1k61A:
2.8		 1zzuA-1k61A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1k61 MATING-TYPE PROTEIN
ALPHA-2
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 144
TRP A 147
GLY A 161
 None
 0.79A 3l35A-1k61A:
0.3
3l35H-1k61A:
undetectable		 3l35A-1k61A:
23.64
3l35H-1k61A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1k61 MATING-TYPE PROTEIN
ALPHA-2
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 144
TRP A 147
GLY A 161
 None
 0.78A 3l35B-1k61A:
undetectable
3l35K-1k61A:
undetectable		 3l35B-1k61A:
23.64
3l35K-1k61A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 1k61 MATING-TYPE PROTEIN
ALPHA-2
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 171
LEU A 165
ASN A 168
ILE A 143
 None
 0.95A 4ww7A-1k61A:
undetectable		 4ww7A-1k61A:
11.88