SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1k68 PHYTOCHROME RESPONSE
REGULATOR RCPA
(Tolypothrix
sp.
PCC
7601) 		3 / 3 ASN A 104
PHE A 109
TYR A 112
 None
 0.77A 4u15A-1k68A:
undetectable		 4u15A-1k68A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1k68 PHYTOCHROME RESPONSE
REGULATOR RCPA
(Tolypothrix
sp.
PCC
7601) 		4 / 8 ILE A  26
SER A  33
LEU A 141
ILE A 136
 None
 0.88A 4xtaB-1k68A:
undetectable		 4xtaB-1k68A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1k68 PHYTOCHROME RESPONSE
REGULATOR RCPA
(Tolypothrix
sp.
PCC
7601) 		4 / 7 PHE A  14
SER A  62
ALA A  61
PRO A  64
 None
 1.12A 5dzkD-1k68A:
undetectable
5dzkR-1k68A:
undetectable		 5dzkD-1k68A:
21.74
5dzkR-1k68A:
3.28