SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DBB_H_STRH229_1
(IGG1-KAPPA DB3 FAB
(HEAVY CHAIN)
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN))		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 8 GLY A 556
GLY A 555
TRP A 128
HIS A 373
 None
None
None
CBI  A 777 (-4.1A)
 0.72A 1dbbH-1k72A:
2.8
1dbbL-1k72A:
3.0		 1dbbH-1k72A:
18.44
1dbbL-1k72A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 10 LEU A 323
VAL A 261
GLY A 264
ALA A 265
LEU A 269
 None
 1.10A 1pxxA-1k72A:
0.0		 1pxxA-1k72A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 323
VAL A 261
GLY A 264
ALA A 265
LEU A 269
 None
 1.10A 1pxxC-1k72A:
0.0		 1pxxC-1k72A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 6 ALA A 164
LEU A 160
SER A 159
SER A  70
 None
 0.91A 1tz8C-1k72A:
undetectable
1tz8D-1k72A:
0.0		 1tz8C-1k72A:
12.89
1tz8D-1k72A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_1
(HYPOTHETICAL PROTEIN
PH0226)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 4 TYR A 425
ARG A 315
ASP A  58
ASP A 120
 None
None
CBI  A 777 ( 4.2A)
None
 1.38A 1ve3A-1k72A:
undetectable		 1ve3A-1k72A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_1
(HYPOTHETICAL PROTEIN
PH0226)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 4 TYR A 425
ARG A 315
ASP A  58
ASP A 120
 None
None
CBI  A 777 ( 4.2A)
None
 1.40A 1ve3B-1k72A:
0.0		 1ve3B-1k72A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 ASP A 124
ARG A 375
ASP A  55
 None
CBI  A 777 (-2.5A)
None
 0.94A 1vptA-1k72A:
undetectable		 1vptA-1k72A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 10 PHE A 566
ASN A 466
GLY A 464
ILE A 461
PHE A 495
 None
 1.12A 1z11C-1k72A:
undetectable		 1z11C-1k72A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 GLN A  20
HIS A 374
ARG A 375
 None
None
CBI  A 777 (-2.5A)
 0.83A 1zlqA-1k72A:
undetectable		 1zlqA-1k72A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 305
LEU A 314
TYR A 351
ALA A 321
ALA A 324
 None
 1.05A 2bm9C-1k72A:
undetectable		 2bm9C-1k72A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 305
LEU A 314
TYR A 351
ALA A 321
ALA A 324
 None
 1.14A 2bm9D-1k72A:
undetectable		 2bm9D-1k72A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 7 SER A 159
ALA A  71
SER A  70
SER A 155
 None
 0.91A 2i91A-1k72A:
undetectable		 2i91A-1k72A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 7 SER A 159
ALA A  71
SER A  70
SER A 155
 None
 0.92A 2i91B-1k72A:
undetectable		 2i91B-1k72A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 GLY A  52
MET A  66
LEU A 160
CYH A 107
VAL A 118
 None
 1.28A 2w8yA-1k72A:
undetectable		 2w8yA-1k72A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 ARG A  21
GLY A  52
SER A 159
 None
 0.61A 2xctB-1k72A:
undetectable		 2xctB-1k72A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 6 ALA A 224
LEU A 221
ALA A 157
THR A 156
ASN A 108
 None
 1.41A 3b6hA-1k72A:
undetectable		 3b6hA-1k72A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 6 ALA A 224
LEU A 221
ALA A 157
THR A 156
ASN A 108
 None
 1.43A 3b6hB-1k72A:
undetectable		 3b6hB-1k72A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 TYR A 341
GLU A 266
ASP A 212
 None
None
CA  A 779 (-2.3A)
 0.87A 3bxoB-1k72A:
undetectable		 3bxoB-1k72A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 VAL A 361
GLY A 397
ALA A 427
GLY A 428
LEU A 433
 None
 0.88A 3ku1A-1k72A:
undetectable		 3ku1A-1k72A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 VAL A 361
GLY A 397
ALA A 427
GLY A 428
LEU A 433
 None
 0.87A 3ku1C-1k72A:
undetectable		 3ku1C-1k72A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 7 TYR A 497
VAL A 459
VAL A 597
ARG A 562
 None
 1.07A 3mssB-1k72A:
undetectable		 3mssB-1k72A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 6 GLU A 503
ILE A 504
ALA A 506
ASN A 539
 CA  A 778 (-2.4A)
None
None
None
 1.14A 3pgyA-1k72A:
undetectable
3pgyB-1k72A:
undetectable		 3pgyA-1k72A:
22.19
3pgyB-1k72A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 8 ASP A 212
ASP A 259
TYR A 263
SER A 209
 CA  A 779 (-2.3A)
CA  A 779 (-4.9A)
None
CA  A 779 (-2.5A)
 1.01A 3qj7A-1k72A:
undetectable
3qj7D-1k72A:
undetectable		 3qj7A-1k72A:
16.23
3qj7D-1k72A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 11 SER A 494
ILE A 493
VAL A 479
PHE A 610
VAL A 459
 None
 1.20A 3rf4A-1k72A:
0.0
3rf4C-1k72A:
undetectable		 3rf4A-1k72A:
11.41
3rf4C-1k72A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 11 SER A 494
ILE A 493
VAL A 479
PHE A 610
VAL A 459
 None
 1.24A 3rf4A-1k72A:
0.0
3rf4B-1k72A:
undetectable		 3rf4A-1k72A:
11.41
3rf4B-1k72A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 11 SER A 494
ILE A 493
VAL A 479
PHE A 610
VAL A 459
 None
 1.23A 3rf4B-1k72A:
0.0
3rf4C-1k72A:
0.0		 3rf4B-1k72A:
11.41
3rf4C-1k72A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 10 ALA A 463
PHE A 566
SER A 521
LEU A 547
VAL A 479
 None
 1.20A 4eilB-1k72A:
undetectable		 4eilB-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 10 VAL A 478
ALA A 463
PHE A 566
SER A 521
VAL A 479
 None
 1.24A 4eilB-1k72A:
undetectable		 4eilB-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 10 VAL A 478
ALA A 463
PHE A 566
SER A 521
VAL A 479
 None
 1.25A 4eilD-1k72A:
undetectable		 4eilD-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 11 ALA A 463
PHE A 566
SER A 521
LEU A 547
VAL A 479
 None
 1.29A 4eilE-1k72A:
undetectable		 4eilE-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 7 PHE A 566
ASN A 466
GLY A 464
ILE A 461
PHE A 495
 None
 1.13A 4ejjA-1k72A:
undetectable		 4ejjA-1k72A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 4 LEU A  73
LEU A  10
GLN A 256
GLU A  79
 None
 1.19A 4i41A-1k72A:
0.0		 4i41A-1k72A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 LYS A 271
LEU A 268
ALA A 270
 None
 0.70A 4ikiA-1k72A:
undetectable		 4ikiA-1k72A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 ALA A 463
PHE A 566
SER A 521
LEU A 547
VAL A 479
 None
 1.26A 4kyaF-1k72A:
undetectable		 4kyaF-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 VAL A 478
ALA A 463
PHE A 566
SER A 521
VAL A 479
 None
 1.25A 4kyaF-1k72A:
undetectable		 4kyaF-1k72A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 SER A 339
ASP A 287
ASP A 280
 None
 0.90A 4mwzA-1k72A:
undetectable		 4mwzA-1k72A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 6 LEU A 399
VAL A 361
ALA A 352
THR A 430
LEU A 433
 None
 0.97A 4o0wA-1k72A:
undetectable		 4o0wA-1k72A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 11 LEU A 305
LEU A 345
GLN A 348
LEU A 314
ALA A 352
 None
 1.21A 4wnuA-1k72A:
0.1		 4wnuA-1k72A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WZM_A_ACTA503_0
(RNA DEPENDENT RNA
POLYMERASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 4 ASP A 195
ASP A 213
ASP A 259
ALA A 151
 None
CA  A 779 (-2.9A)
CA  A 779 (-4.9A)
CA  A 779 ( 4.6A)
 1.47A 4wzmA-1k72A:
0.0		 4wzmA-1k72A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 5 TYR A 198
GLY A 203
TYR A 116
GLY A 119
 GOL  A 783 (-4.6A)
None
None
None
 1.07A 5ayfA-1k72A:
undetectable		 5ayfA-1k72A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 7 ASN A 419
VAL A 400
ALA A 398
GLY A 363
 None
 0.89A 5fpdA-1k72A:
undetectable		 5fpdA-1k72A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 7 ASN A 419
VAL A 400
ALA A 398
GLY A 363
 None
 0.89A 5fpdB-1k72A:
undetectable		 5fpdB-1k72A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 323
VAL A 261
GLY A 264
ALA A 265
LEU A 269
 None
 1.10A 5ikqA-1k72A:
0.0		 5ikqA-1k72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 TYR A  78
SER A  76
TRP A 220
 None
 1.04A 5n8jB-1k72A:
0.0		 5n8jB-1k72A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 TYR A  78
SER A  76
TRP A 220
 None
 0.98A 5n8jA-1k72A:
undetectable		 5n8jA-1k72A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 TYR A  78
SER A  76
TRP A 220
 None
 0.99A 5n8jD-1k72A:
undetectable		 5n8jD-1k72A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 LYS A 496
PRO A 601
LYS A 608
 None
 1.28A 5y9yA-1k72A:
undetectable		 5y9yA-1k72A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		3 / 3 TYR A  68
PRO A  65
LEU A  64
 None
 0.95A 6beoA-1k72A:
undetectable		 6beoA-1k72A:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 9 VAL A 261
HIS A 262
GLY A 264
LEU A  73
ASP A 424
 None
 1.21A 6c2mC-1k72A:
undetectable		 6c2mC-1k72A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		4 / 9 PHE A 322
LEU A 314
SER A 359
ASP A 350
 None
 0.86A 6c2mD-1k72A:
undetectable		 6c2mD-1k72A:
10.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1k72 ENDOGLUCANASE 9G
([Clostridium]
cellulolyticum) 		5 / 12 LEU A 588
PHE A 495
VAL A 479
THR A 526
VAL A 545
 None
 1.21A 6djzA-1k72A:
1.6		 6djzA-1k72A:
15.99