SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 VAL N  46
VAL N 101
TRP N  43
 None
 0.96A 1bdwA-1k7sN:
undetectable
1bdwB-1k7sN:
undetectable		 1bdwA-1k7sN:
5.05
1bdwB-1k7sN:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 VAL N 101
VAL N  81
LEU N  50
LEU N  49
 None
 0.82A 1cqpA-1k7sN:
undetectable
1cqpB-1k7sN:
undetectable		 1cqpA-1k7sN:
20.82
1cqpB-1k7sN:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XPQ_A_SPMA924_1
(FMS1 PROTEIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 11 PHE N 238
LEU N 131
PHE N 197
LEU N 196
TYR N 158
 None
 1.43A 1xpqA-1k7sN:
2.2		 1xpqA-1k7sN:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 VAL N 287
THR N 181
PHE N 274
PHE N 238
HIS N 240
 None
 1.29A 2vdyA-1k7sN:
undetectable		 2vdyA-1k7sN:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 VAL N 287
THR N 181
PHE N 191
PHE N 238
HIS N 240
 None
 1.29A 2vdyB-1k7sN:
undetectable		 2vdyB-1k7sN:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 VAL N 287
THR N 181
PHE N 274
PHE N 238
HIS N 240
 None
 1.25A 2vdyB-1k7sN:
undetectable		 2vdyB-1k7sN:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 PHE N 238
LEU N 227
MET N 246
MET N 188
LEU N 177
 None
 1.46A 2xkwA-1k7sN:
undetectable		 2xkwA-1k7sN:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 10 ALA N 209
GLN N 267
LEU N 236
LEU N 177
ARG N 175
 None
 1.14A 2xn6A-1k7sN:
0.0
2xn6B-1k7sN:
0.0		 2xn6A-1k7sN:
24.59
2xn6B-1k7sN:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 10 ALA N 209
GLN N 267
LEU N 236
LEU N 177
ARG N 175
 None
 1.07A 2xn7A-1k7sN:
0.0
2xn7B-1k7sN:
0.0		 2xn7A-1k7sN:
24.59
2xn7B-1k7sN:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 MET N 141
ARG N 120
VAL N 101
ILE N  38
 None
 0.90A 2yfbA-1k7sN:
undetectable		 2yfbA-1k7sN:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 TRP N 273
LEU N  44
GLU N  42
TRP N 217
 None
None
ALB  N 500 ( 3.9A)
ALB  N 500 (-3.7A)
 1.24A 3dzgA-1k7sN:
undetectable		 3dzgA-1k7sN:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 TRP N 273
LEU N  44
GLU N  42
TRP N 217
 None
None
ALB  N 500 ( 3.9A)
ALB  N 500 (-3.7A)
 1.31A 3dzgB-1k7sN:
undetectable		 3dzgB-1k7sN:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 6 TRP N 273
LEU N  44
GLU N  42
TRP N 217
 None
None
ALB  N 500 ( 3.9A)
ALB  N 500 (-3.7A)
 1.37A 3ropA-1k7sN:
undetectable		 3ropA-1k7sN:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 THR N 180
ASN N 208
LEU N 201
PHE N 238
 None
 1.16A 4awuA-1k7sN:
undetectable		 4awuA-1k7sN:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		5 / 12 VAL N 287
THR N 181
PHE N 274
PHE N 238
HIS N 240
 None
 1.31A 4c49B-1k7sN:
undetectable		 4c49B-1k7sN:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		3 / 3 MET N 250
ASP N 239
PHE N 238
 None
 1.06A 4xeyA-1k7sN:
0.0		 4xeyA-1k7sN:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 ILE N 292
LEU N 288
THR N 180
LEU N 179
 None
 0.89A 5b1aA-1k7sN:
undetectable
5b1aJ-1k7sN:
undetectable		 5b1aA-1k7sN:
20.17
5b1aJ-1k7sN:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 ILE N 292
LEU N 288
THR N 180
LEU N 179
 None
 0.92A 5b3sA-1k7sN:
undetectable
5b3sJ-1k7sN:
0.0		 5b3sA-1k7sN:
20.17
5b3sJ-1k7sN:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 6 VAL N 287
ALA N 291
GLN N 267
VAL N 269
 None
 0.96A 5i8fA-1k7sN:
0.0		 5i8fA-1k7sN:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 ILE N 292
LEU N 288
THR N 180
LEU N 179
 None
 0.90A 5xdxA-1k7sN:
undetectable
5xdxJ-1k7sN:
undetectable		 5xdxA-1k7sN:
20.17
5xdxJ-1k7sN:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 6 TYR N  65
LEU N  48
GLU N  42
LEU N  44
 None
None
ALB  N 500 ( 3.9A)
None
 1.41A 5xooA-1k7sN:
undetectable		 5xooA-1k7sN:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 ILE N 292
LEU N 288
THR N 180
LEU N 179
 None
 0.89A 5zcpA-1k7sN:
undetectable
5zcpJ-1k7sN:
undetectable		 5zcpA-1k7sN:
20.17
5zcpJ-1k7sN:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1k7s FERRICHROME-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		4 / 7 ILE N 292
LEU N 288
THR N 180
LEU N 179
 None
 0.89A 5zcqA-1k7sN:
undetectable
5zcqJ-1k7sN:
0.0		 5zcqA-1k7sN:
20.17
5zcqJ-1k7sN:
12.08