SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 10 GLY A 165
VAL A 166
GLY A 167
ASN A 160
VAL A 163
 None
 1.29A 1pwyE-1k82A:
undetectable		 1pwyE-1k82A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		6 / 12 LEU A 196
LEU A 157
ALA A 178
ALA A 203
THR A 260
ILE A 153
 None
 1.33A 3c6gA-1k82A:
undetectable		 3c6gA-1k82A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 12 LEU A 157
ALA A 178
ALA A 203
THR A 260
ILE A 153
 None
 1.15A 3czhB-1k82A:
0.0		 3czhB-1k82A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 7 LEU A 216
PRO A   4
SER A 208
GLY A 167
 None
 1.12A 3hcnA-1k82A:
undetectable		 3hcnA-1k82A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		3 / 3 THR A 105
SER A  76
ARG A  78
 None
 0.82A 3phnA-1k82A:
0.0		 3phnA-1k82A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 5 GLY A  75
ASP A 106
ARG A 108
MET A 158
 None
 1.43A 3qx3A-1k82A:
undetectable		 3qx3A-1k82A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 5 GLY A  75
ASP A 106
ARG A 108
MET A 158
 None
 1.45A 3qx3B-1k82A:
0.3		 3qx3B-1k82A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 10 VAL A  92
TRP A 113
ILE A  40
LEU A  17
LEU A  60
 None
 1.28A 4jtqA-1k82A:
undetectable		 4jtqA-1k82A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 12 ILE A  22
LEU A  43
VAL A  36
GLY A  30
LEU A  17
 None
 1.21A 5ienA-1k82A:
1.9		 5ienA-1k82A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 12 ILE A  22
LEU A  43
VAL A  36
LEU A  77
GLY A  30
 None
 1.09A 5ienA-1k82A:
1.9		 5ienA-1k82A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 7 LEU A 185
ALA A 152
ILE A 180
LEU A 189
 None
 0.97A 5te8C-1k82A:
undetectable		 5te8C-1k82A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 5 GLY A  75
ASP A 106
ARG A 108
MET A 158
 None
 1.45A 5zrfB-1k82A:
undetectable		 5zrfB-1k82A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		4 / 4 GLY A  75
ASP A 106
ARG A 108
MET A 158
 None
 1.45A 5zrfA-1k82A:
0.0		 5zrfA-1k82A:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1k82 FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE
(Escherichia
coli) 		5 / 12 LEU A 142
SER A 172
ILE A 153
THR A 260
LEU A 196
 None
 1.18A 6djzB-1k82A:
0.0		 6djzB-1k82A:
22.26