SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k85'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 1k85 CHITINASE A1
(Bacillus
circulans) 		4 / 8 ALA A 570
SER A 575
THR A 577
SER A 612
 None
 0.79A 4ikkA-1k85A:
undetectable
4ikkB-1k85A:
undetectable		 4ikkA-1k85A:
22.46
4ikkB-1k85A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1k85 CHITINASE A1
(Bacillus
circulans) 		5 / 12 VAL A 589
LEU A 600
ALA A 626
SER A 583
THR A 602
 None
 1.27A 5nd3B-1k85A:
undetectable		 5nd3B-1k85A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1k85 CHITINASE A1
(Bacillus
circulans) 		4 / 7 GLY A 597
PHE A 622
VAL A 624
SER A 641
 None
 0.78A 6hu9S-1k85A:
0.0
6hu9q-1k85A:
undetectable		 6hu9S-1k85A:
16.00
6hu9q-1k85A:
22.56