SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1k8m E2 COMPONENT OF
BRANCHED-CHAIN
ALPHA-KETOACID
DEHYDROGENASE
(Homo
sapiens) 		3 / 3 ASP A  36
THR A  20
GLU A  40
 None
 0.63A 2zifB-1k8mA:
undetectable		 2zifB-1k8mA:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 1k8m E2 COMPONENT OF
BRANCHED-CHAIN
ALPHA-KETOACID
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 ASP A  85
SER A  10
CYH A  39
LEU A  75
 None
 1.04A 3m0wE-1k8mA:
undetectable
3m0wF-1k8mA:
undetectable
3m0wG-1k8mA:
undetectable
3m0wH-1k8mA:
undetectable		 3m0wE-1k8mA:
19.61
3m0wF-1k8mA:
19.61
3m0wG-1k8mA:
19.61
3m0wH-1k8mA:
19.61