SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 1k9m RIBOSOMAL PROTEIN
L10E
(Haloarcula
marismortui) 		5 / 12 ILE J  23
VAL J  92
ILE J  93
VAL J 119
PRO J 118
 None
 0.89A 3kpdC-1k9mJ:
0.0		 3kpdC-1k9mJ:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 1k9m RIBOSOMAL PROTEIN
L10E
(Haloarcula
marismortui) 		5 / 10 VAL J  92
ILE J  23
GLY J  25
PRO J  89
ALA J 122
 None
 1.01A 3t3cB-1k9mJ:
undetectable		 3t3cB-1k9mJ:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 1k9m RIBOSOMAL PROTEIN
L10E
(Haloarcula
marismortui) 		4 / 7 ALA J 134
ALA J 145
GLU J 144
SER J  75
 None
 0.89A 4r1zB-1k9mJ:
undetectable		 4r1zB-1k9mJ:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 1k9m RIBOSOMAL PROTEIN
L10E
(Haloarcula
marismortui) 		4 / 6 VAL J 142
ALA J 134
VAL J 136
TYR J  81
 None
 1.02A 5i8fA-1k9mJ:
0.0		 5i8fA-1k9mJ:
20.63