SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1k9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1k9o ALASERPIN
(Manduca
sexta) 		4 / 8 PHE I 379
LEU I 100
GLY I 182
ASP I  99
 None
 0.98A 1rmtC-1k9oI:
undetectable		 1rmtC-1k9oI:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 9 LEU I  54
LEU I 296
ALA I 309
LEU I 312
PHE I 305
 None
 1.13A 1tbfA-1k9oI:
undetectable		 1tbfA-1k9oI:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 10 LEU I  69
LEU I  73
ILE I 301
ILE I 178
LEU I  51
 None
 1.18A 1wopA-1k9oI:
0.0		 1wopA-1k9oI:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1k9o ALASERPIN
(Manduca
sexta) 		3 / 3 LEU I  54
PRO I  53
LEU I  57
 None
 0.47A 2po5B-1k9oI:
undetectable		 2po5B-1k9oI:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1k9o ALASERPIN
(Manduca
sexta) 		3 / 3 LEU I  54
PRO I  53
LEU I  57
 None
 0.51A 2po7B-1k9oI:
undetectable		 2po7B-1k9oI:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 12 GLY I 381
ILE I 363
LEU I 281
VAL I 335
MET I 241
 None
 1.01A 3adxB-1k9oI:
0.6		 3adxB-1k9oI:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 6 VAL I  92
SER I 104
LEU I  59
ILE I 106
LEU I  88
 None
 1.32A 3kk6A-1k9oI:
undetectable		 3kk6A-1k9oI:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 10 VAL I  92
ASN I  89
PHE I  85
ILE I 376
PHE I  48
 None
 1.18A 3t3qA-1k9oI:
0.0		 3t3qA-1k9oI:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 10 VAL I  92
ASN I  89
PHE I  85
ILE I 376
PHE I  48
 None
 1.14A 3t3qB-1k9oI:
0.0		 3t3qB-1k9oI:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 10 VAL I  92
ASN I  89
PHE I  85
ILE I 376
PHE I  48
 None
 1.14A 3t3qC-1k9oI:
undetectable		 3t3qC-1k9oI:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 1k9o ALASERPIN
(Manduca
sexta) 		5 / 10 VAL I  92
ASN I  89
PHE I  85
ILE I 376
PHE I  48
 None
 1.16A 3t3qD-1k9oI:
0.0		 3t3qD-1k9oI:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 1k9o ALASERPIN
(Manduca
sexta) 		4 / 7 GLN I  56
LEU I  73
THR I  81
THR I  27
 None
 1.11A 4mbsA-1k9oI:
0.0		 4mbsA-1k9oI:
22.54