SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		5 / 10 GLY A  82
LEU A 143
TYR A 144
THR A  80
GLY A  81
 None
 1.22A 1kvlA-1kagA:
undetectable		 1kvlA-1kagA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		4 / 7 TYR A 144
GLY A  81
ASP A  36
ASP A  46
 None
 1.07A 2g72B-1kagA:
undetectable		 2g72B-1kagA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		4 / 8 SER A  18
PHE A  51
GLY A  48
ILE A  39
 None
 0.81A 3aodA-1kagA:
undetectable		 3aodA-1kagA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		4 / 8 ILE A  67
SER A  35
ILE A  39
ARG A  42
 None
 1.12A 3sfeB-1kagA:
0.0
3sfeC-1kagA:
undetectable		 3sfeB-1kagA:
18.15
3sfeC-1kagA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		4 / 6 ARG A  97
LEU A  94
ARG A  91
ARG A  93
 None
 1.24A 5l6eA-1kagA:
undetectable
5l6eB-1kagA:
0.0		 5l6eA-1kagA:
21.03
5l6eB-1kagA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		3 / 3 LYS A 121
LYS A  17
SER A  18
 None
 1.37A 5odiA-1kagA:
undetectable		 5odiA-1kagA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1kag SHIKIMATE KINASE I
(Escherichia
coli) 		5 / 12 PRO A 121
GLY A  14
GLY A  82
GLY A  11
ALA A  79
 None
 1.03A 6nj9K-1kagA:
2.2		 6nj9K-1kagA:
19.47