SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kaw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MV7_A_PPFA501_1 (BIOTIN CARBOXYLASE)	1kaw	SINGLE-STRANDED DNA BINDING PROTEIN (Escherichia coli)	4 / 7	ASN A 31 VAL A 102 GLU A 100 ARG A 84	None	1.09A	4mv7A-1kawA: undetectable	4mv7A-1kawA: 15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNV_A_QI9A602_0 (CYTOCHROME P450 2D6)	1kaw	SINGLE-STRANDED DNA BINDING PROTEIN (Escherichia coli)	5 / 9	LEU A 14 THR A 108 VAL A 103 VAL A 57 LEU A 63	None	1.25A	4wnvA-1kawA: undetectable	4wnvA-1kawA: 14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_D_CCSD14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2 PROGRAMMED CELL DEATH 1 LIGAND 1)	1kaw	SINGLE-STRANDED DNA BINDING PROTEIN (Escherichia coli)	5 / 12	PHE A 60 LEU A 63 GLY A 81 GLY A 106 VAL A 105	None	1.33A	5o4yD-1kawA: undetectable 5o4yE-1kawA: undetectable	5o4yD-1kawA: 5.93 5o4yE-1kawA: 19.71