SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		5 / 12 VAL H 163
VAL H 181
SER H 179
ASN H 196
ASN H 155
 None
 1.38A 2y03A-1kb5H:
undetectable		 2y03A-1kb5H:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		5 / 12 VAL H 163
VAL H 181
SER H 179
ASN H 196
ASN H 155
 None
 1.43A 2y03B-1kb5H:
undetectable		 2y03B-1kb5H:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		5 / 12 VAL H 163
VAL H 181
SER H 179
ASN H 196
ASN H 155
 None
 1.30A 3nyaA-1kb5H:
undetectable		 3nyaA-1kb5H:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		3 / 3 ASP H  52
GLY H  31
TYR H  54
 None
 0.64A 3w9tC-1kb5H:
undetectable		 3w9tC-1kb5H:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		3 / 3 ASP H  52
GLY H  31
TYR H  54
 None
 0.63A 3w9tG-1kb5H:
undetectable		 3w9tG-1kb5H:
20.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 1kb5 ANTIBODY DESIRE-1
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.36A 4m7kH-1kb5H:
27.0		 4m7kH-1kb5H:
66.07