SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kcg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 TRP C 138
PHE C 162
TRP C 119
 None
 1.06A 1r15C-1kcgC:
undetectable		 1r15C-1kcgC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 TRP C 138
PHE C 162
TRP C 119
 None
 1.06A 1r15F-1kcgC:
undetectable		 1r15F-1kcgC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 TRP C 138
PHE C 162
TRP C 119
 None
 1.06A 1r15G-1kcgC:
undetectable		 1r15G-1kcgC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 TRP C 138
PHE C 162
TRP C 119
 None
 1.06A 1r15H-1kcgC:
undetectable		 1r15H-1kcgC:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		4 / 7 PHE C 128
SER C 122
ILE C  20
LYS C  98
 None
 0.84A 1sbrB-1kcgC:
0.0		 1sbrB-1kcgC:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 TRP C 152
TRP C 138
THR C 159
 None
 1.36A 4bboB-1kcgC:
2.1		 4bboB-1kcgC:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 1kcg ULBP3 PROTEIN
(Homo
sapiens) 		3 / 3 MET C 179
GLN C  60
TYR C  62
 GSH  C 999 (-4.6A)
None
None
 1.07A 4udcA-1kcgC:
1.8		 4udcA-1kcgC:
18.98