SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kcw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 HIS A 980
HIS A1020
ALA A 166
HIS A 163
HIS A 101
 CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
None
CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
 1.29A 1a4lC-1kcwA:
undetectable		 1a4lC-1kcwA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 8 HIS A1022
HIS A 103
HIS A 978
LEU A1018
HIS A 163
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
None
CU  A1050 (-3.3A)
 1.39A 1azmA-1kcwA:
undetectable		 1azmA-1kcwA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ALA A 854
VAL A 880
TRP A 858
 None
 0.86A 1c4dA-1kcwA:
undetectable
1c4dB-1kcwA:
undetectable		 1c4dA-1kcwA:
2.18
1c4dB-1kcwA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 TRP A 858
ALA A 854
VAL A 880
 None
 0.86A 1c4dA-1kcwA:
undetectable
1c4dB-1kcwA:
undetectable		 1c4dA-1kcwA:
2.18
1c4dB-1kcwA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ALA A 854
VAL A 880
TRP A 858
 None
 0.77A 1c4dC-1kcwA:
undetectable
1c4dD-1kcwA:
undetectable		 1c4dC-1kcwA:
2.18
1c4dD-1kcwA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 TRP A 858
ALA A 854
VAL A 880
 None
 0.73A 1c4dC-1kcwA:
undetectable
1c4dD-1kcwA:
undetectable		 1c4dC-1kcwA:
2.18
1c4dD-1kcwA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 THR A 583
THR A 394
GLU A 391
THR A 380
 None
 1.34A 1d4fB-1kcwA:
0.0		 1d4fB-1kcwA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 LEU A 902
LEU A1007
LEU A 965
THR A1003
 None
 0.97A 1dvtA-1kcwA:
0.0
1dvtB-1kcwA:
0.0		 1dvtA-1kcwA:
8.42
1dvtB-1kcwA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 8 HIS A 980
ILE A1027
HIS A 978
HIS A1020
HIS A 163
 CU  A1050 (-3.0A)
None
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.3A)
 1.14A 1ei6D-1kcwA:
0.0		 1ei6D-1kcwA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 161
HIS A 163
HIS A1020
HIS A 978
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
 1.22A 1fweC-1kcwA:
undetectable		 1fweC-1kcwA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 ASN A 448
TYR A 406
LEU A 404
SER A 522
 None
 1.08A 1hk3A-1kcwA:
0.0		 1hk3A-1kcwA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.56A 1oe1A-1kcwA:
21.8		 1oe1A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.46A 1oe1A-1kcwA:
21.8		 1oe1A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.55A 1oe2A-1kcwA:
11.8		 1oe2A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.46A 1oe2A-1kcwA:
11.8		 1oe2A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.57A 1oe3A-1kcwA:
21.6		 1oe3A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.49A 1oe3A-1kcwA:
21.6		 1oe3A-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 ILE A 578
GLN A 596
ASP A 592
PHE A 595
GLU A 575
 None
 1.41A 1p5zB-1kcwA:
undetectable		 1p5zB-1kcwA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ARG A 845
VAL A 880
TRP A 858
 None
 1.24A 1qwcA-1kcwA:
0.0		 1qwcA-1kcwA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ILE A 159
ILE A 175
THR A 157
 None
 0.60A 1rg7A-1kcwA:
undetectable		 1rg7A-1kcwA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 ASP A 576
GLU A 575
THR A 532
LEU A 572
LEU A 573
 None
 1.07A 1u18B-1kcwA:
undetectable		 1u18B-1kcwA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
GLU A 112
HIS A 980
HIS A 978
 CU  A1052 (-3.2A)
None
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.31A 1uttA-1kcwA:
undetectable		 1uttA-1kcwA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ARG A 845
VAL A 880
TRP A 858
 None
 1.27A 1vagA-1kcwA:
undetectable		 1vagA-1kcwA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 GLY A 536
ILE A 357
ALA A 359
ILE A 530
SER A 522
 None
 1.09A 1ve3B-1kcwA:
undetectable		 1ve3B-1kcwA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A 837
GLU A 823
HIS A 816
 None
 0.80A 1xwfA-1kcwA:
0.0		 1xwfA-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A 837
GLU A 823
HIS A 816
 None
 0.79A 1xwfB-1kcwA:
0.0		 1xwfB-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A 837
GLU A 823
HIS A 816
 None
 0.75A 1xwfC-1kcwA:
0.0		 1xwfC-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A1034
GLU A 112
HIS A 978
 None
None
CU  A1052 ( 3.2A)
 0.91A 1xwfC-1kcwA:
0.0		 1xwfC-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A 837
GLU A 823
HIS A 816
 None
 0.76A 1xwfD-1kcwA:
0.0		 1xwfD-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A1034
GLU A 112
HIS A 978
 None
None
CU  A1052 ( 3.2A)
 0.91A 1xwfD-1kcwA:
0.0		 1xwfD-1kcwA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 978
HIS A 103
HIS A 101
GLY A 981
TYR A 107
 CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
O  A1058 ( 4.9A)
None
 1.20A 1zz1A-1kcwA:
undetectable		 1zz1A-1kcwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ASP A  29
ILE A  35
VAL A 204
 None
 0.69A 2avvD-1kcwA:
undetectable		 2avvD-1kcwA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 ALA A  80
TYR A   5
ILE A 105
ILE A  78
 None
 1.22A 2dcfA-1kcwA:
0.0		 2dcfA-1kcwA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.21A 2f162-1kcwA:
undetectable		 2f162-1kcwA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.19A 2f16N-1kcwA:
undetectable		 2f16N-1kcwA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.44A 2fqdA-1kcwA:
14.0		 2fqdA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.36A 2fqdA-1kcwA:
14.0		 2fqdA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.40A 2fqeA-1kcwA:
14.0		 2fqeA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.29A 2fqeA-1kcwA:
14.0		 2fqeA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.74A 2fqeA-1kcwA:
13.9		 2fqeA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.94A 2fqeA-1kcwA:
13.9		 2fqeA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.37A 2fqfA-1kcwA:
13.9		 2fqfA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.28A 2fqfA-1kcwA:
13.9		 2fqfA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.73A 2fqfA-1kcwA:
13.9		 2fqfA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.36A 2fqfA-1kcwA:
13.9		 2fqfA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.90A 2fqfA-1kcwA:
13.9		 2fqfA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.35A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.32A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.68A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.33A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.87A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.37A 2fqgA-1kcwA:
13.9		 2fqgA-1kcwA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 VAL A1023
VAL A 273
ASP A 905
 CU  A1055 ( 4.6A)
None
None
 0.71A 2fumD-1kcwA:
undetectable		 2fumD-1kcwA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 LEU A 140
ALA A  80
ILE A  77
VAL A  88
VAL A  86
 None
 0.95A 2nnkA-1kcwA:
undetectable		 2nnkA-1kcwA:
7.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 10 PHE A 566
GLN A 612
GLY A 428
ASN A 605
PHE A 562
 None
 1.34A 2ok6A-1kcwA:
0.3
2ok6H-1kcwA:
0.0		 2ok6A-1kcwA:
16.32
2ok6H-1kcwA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 SER A 384
GLY A 383
HIS A 602
ASP A 567
 None
None
CU  A1054 ( 3.4A)
None
 1.18A 2oxtC-1kcwA:
undetectable		 2oxtC-1kcwA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
GLU A 112
HIS A 980
HIS A 978
 CU  A1052 (-3.2A)
None
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.33A 2ozrE-1kcwA:
undetectable		 2ozrE-1kcwA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 HIS A 103
HIS A 161
ILE A 170
HIS A1022
HIS A 978
 CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
None
CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
 0.97A 2pgrA-1kcwA:
undetectable		 2pgrA-1kcwA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ALA A 114
TYR A 116
ASP A 127
HIS A 101
 None
None
None
CU  A1052 (-3.2A)
 0.90A 2pncA-1kcwA:
undetectable		 2pncA-1kcwA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ALA A 114
TYR A 116
TYR A 107
HIS A 101
 None
None
None
CU  A1052 (-3.2A)
 1.37A 2pncA-1kcwA:
undetectable		 2pncA-1kcwA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 ASP A  29
GLU A  31
HIS A  32
SER A  33
 None
 1.11A 2q0iA-1kcwA:
undetectable		 2q0iA-1kcwA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 103
HIS A 101
HIS A 161
HIS A 978
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
 1.10A 2wkoA-1kcwA:
2.1		 2wkoA-1kcwA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A1020
HIS A 980
HIS A1022
 CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
CU  A1051 (-3.2A)
 1.11A 2wkoA-1kcwA:
2.1		 2wkoA-1kcwA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.53A 2xxgA-1kcwA:
21.6		 2xxgA-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.46A 2xxgA-1kcwA:
21.6		 2xxgA-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.54A 2xxgC-1kcwA:
21.6		 2xxgC-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.48A 2xxgC-1kcwA:
21.6		 2xxgC-1kcwA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 TYR A 871
SER A 872
GLN A 866
ILE A 875
 None
 0.94A 2xz5A-1kcwA:
0.8
2xz5B-1kcwA:
0.7		 2xz5A-1kcwA:
12.11
2xz5B-1kcwA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 TYR A 871
SER A 872
GLN A 866
ILE A 875
 None
 1.00A 2xz5B-1kcwA:
0.7
2xz5E-1kcwA:
0.2		 2xz5B-1kcwA:
12.11
2xz5E-1kcwA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 THR A 294
GLN A 320
ASP A 293
SER A 663
 None
 1.18A 2xz5C-1kcwA:
0.0
2xz5D-1kcwA:
1.1		 2xz5C-1kcwA:
12.11
2xz5D-1kcwA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 ILE A 999
MET A 968
PRO A1001
VAL A 801
 None
 1.19A 2ygoA-1kcwA:
2.0		 2ygoA-1kcwA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 PHE A 748
ASN A 746
PHE A 947
 None
 0.55A 2zbuD-1kcwA:
undetectable		 2zbuD-1kcwA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.17A 2zweA-1kcwA:
undetectable
2zweB-1kcwA:
undetectable		 2zweA-1kcwA:
14.47
2zweB-1kcwA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.20A 2zwfA-1kcwA:
undetectable
2zwfB-1kcwA:
0.0		 2zwfA-1kcwA:
14.47
2zwfB-1kcwA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.22A 2zwgA-1kcwA:
undetectable
2zwgB-1kcwA:
0.0		 2zwgA-1kcwA:
14.47
2zwgB-1kcwA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 LEU A 786
VAL A 777
ARG A 766
 None
 0.87A 3b0wB-1kcwA:
0.0		 3b0wB-1kcwA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 10 TYR A 838
ILE A 717
TYR A 765
THR A 822
VAL A 820
 None
 1.31A 3burB-1kcwA:
undetectable		 3burB-1kcwA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 ASN A 244
MET A 201
PHE A 267
ILE A 175
TYR A 160
 None
 0.85A 3em0A-1kcwA:
0.0		 3em0A-1kcwA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 ASN A 244
MET A 201
PHE A 267
LEU A  52
ILE A 175
 None
 0.95A 3em0B-1kcwA:
undetectable		 3em0B-1kcwA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 MET A 617
GLY A 614
GLN A 612
LEU A 561
MET A 668
 None
 1.25A 3h52B-1kcwA:
undetectable		 3h52B-1kcwA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 MET A 617
GLY A 614
GLN A 612
LEU A 561
MET A 668
 None
 1.38A 3h52D-1kcwA:
undetectable		 3h52D-1kcwA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ILE A 803
TYR A 716
ILE A 717
GLN A 767
 None
 0.93A 3hgxA-1kcwA:
undetectable		 3hgxA-1kcwA:
7.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 8 TYR A 765
TYR A 861
PHE A 805
ILE A 804
 None
 1.07A 3jz0B-1kcwA:
0.0		 3jz0B-1kcwA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 LEU A1018
HIS A 103
HIS A 161
HIS A1022
 None
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 1.00A 3kecA-1kcwA:
undetectable		 3kecA-1kcwA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 ILE A 159
HIS A 163
HIS A 980
HIS A1020
 None
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.98A 3ljgA-1kcwA:
undetectable		 3ljgA-1kcwA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.19A 3mg02-1kcwA:
undetectable
3mg0V-1kcwA:
undetectable		 3mg02-1kcwA:
11.21
3mg0V-1kcwA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.18A 3mg0N-1kcwA:
undetectable		 3mg0N-1kcwA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A 161
HIS A 101
HIS A 103
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.84A 3mihA-1kcwA:
undetectable		 3mihA-1kcwA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NJZ_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 ALA A 300
HIS A 101
HIS A 163
HIS A 980
ILE A 170
 None
CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
None
 1.40A 3njzA-1kcwA:
0.0		 3njzA-1kcwA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 TYR A 107
GLY A 113
ASP A 128
 None
 0.71A 3ou6C-1kcwA:
undetectable		 3ou6C-1kcwA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 LEU A  54
TYR A  53
ALA A  51
GLY A 173
TRP A 211
 None
 1.16A 3ou7A-1kcwA:
undetectable		 3ou7A-1kcwA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 GLU A 651
PRO A 513
ARG A 649
GLY A 650
 None
 1.39A 3oxvA-1kcwA:
undetectable		 3oxvA-1kcwA:
7.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ILE A 842
VAL A 801
ARG A 713
TYR A 715
 None
 0.75A 3p6hA-1kcwA:
undetectable		 3p6hA-1kcwA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 276
CYH A 319
HIS A 324
LEU A 329
 CU  A1049 ( 3.1A)
CU  A1049 ( 2.0A)
CU  A1049 ( 3.1A)
CU  A1049 (-4.7A)
 0.53A 3qpkA-1kcwA:
8.0		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A1022
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.28A 3qpkA-1kcwA:
8.0		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.78A 3qpkA-1kcwA:
17.2		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 3qpkA-1kcwA:
17.2		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.97A 3qpkA-1kcwA:
17.2		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 3qpkA-1kcwA:
17.2		 3qpkA-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A1022
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.28A 3qpkB-1kcwA:
15.7		 3qpkB-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.70A 3qpkB-1kcwA:
15.7		 3qpkB-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.31A 3qpkB-1kcwA:
15.7		 3qpkB-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.90A 3qpkB-1kcwA:
15.7		 3qpkB-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.34A 3qpkB-1kcwA:
15.7		 3qpkB-1kcwA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ASN A 448
ALA A 359
LYS A 449
 None
 0.96A 3runA-1kcwA:
0.0		 3runA-1kcwA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A 602
SER A 629
ASN A 632
 CU  A1054 ( 3.4A)
None
None
 0.70A 3s8pB-1kcwA:
0.0		 3s8pB-1kcwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 PHE A  73
SER A 203
SER A 242
 None
 1.00A 3ufgB-1kcwA:
undetectable		 3ufgB-1kcwA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ILE A 999
PHE A 979
PHE A 984
LEU A1007
 None
 0.89A 3v7pA-1kcwA:
undetectable		 3v7pA-1kcwA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 8 HIS A1022
HIS A 103
HIS A 978
LEU A1018
HIS A 163
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
None
CU  A1050 (-3.3A)
 1.38A 3w6hA-1kcwA:
undetectable		 3w6hA-1kcwA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 9 HIS A1022
HIS A 103
HIS A 978
LEU A1018
HIS A 163
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
None
CU  A1050 (-3.3A)
 1.39A 3w6hB-1kcwA:
undetectable		 3w6hB-1kcwA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.26A 3w9tA-1kcwA:
0.0		 3w9tA-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.25A 3w9tB-1kcwA:
0.0		 3w9tB-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.26A 3w9tC-1kcwA:
0.0		 3w9tC-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.25A 3w9tD-1kcwA:
0.0		 3w9tD-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.25A 3w9tE-1kcwA:
0.0		 3w9tE-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.27A 3w9tF-1kcwA:
0.0		 3w9tF-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 VAL A 764
GLY A 873
TYR A 813
ASP A 869
 None
 1.26A 3w9tG-1kcwA:
0.0		 3w9tG-1kcwA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 PHE A 446
LEU A 404
GLY A 533
ILE A 456
 None
 0.78A 3wrkA-1kcwA:
0.0		 3wrkA-1kcwA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 HIS A1020
ASP A 165
HIS A 161
HIS A1028
 CU  A1050 (-3.2A)
None
CU  A1051 (-3.3A)
None
 1.50A 3zodA-1kcwA:
0.0		 3zodA-1kcwA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 ASP A 118
THR A1034
GLU A 112
LYS A 109
 None
 1.43A 4a3pA-1kcwA:
0.0		 4a3pA-1kcwA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 THR A 837
ILE A 803
LYS A 802
PHE A 773
 None
 1.48A 4acaC-1kcwA:
undetectable		 4acaC-1kcwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 637
CYH A 680
HIS A 685
MET A 690
 CU  A1053 ( 3.1A)
CU  A1053 ( 2.0A)
CU  A1053 ( 3.1A)
CU  A1053 ( 3.0A)
 0.32A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 975
CYH A1021
HIS A1026
MET A1031
 CU  A1055 ( 3.2A)
CU  A1055 ( 2.0A)
CU  A1055 ( 3.1A)
CU  A1055 ( 3.2A)
 0.32A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 103
HIS A 161
HIS A 978
HIS A1022
 CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
 0.61A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 101
HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.59A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 978
HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.38A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 980
HIS A 978
HIS A 161
HIS A 101
HIS A 103
 CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 1.35A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A1020
HIS A 978
HIS A 163
HIS A 980
HIS A 101
 CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
 1.39A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.66A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.35A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.86A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.38A 4ef3A-1kcwA:
13.9		 4ef3A-1kcwA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 ILE A 879
PRO A 857
GLY A 967
ALA A 898
 None
 0.92A 4g0uB-1kcwA:
undetectable		 4g0uB-1kcwA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ASP A 372
VAL A 388
ASN A 611
 None
 0.81A 4lmnA-1kcwA:
undetectable		 4lmnA-1kcwA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 978
HIS A 103
HIS A 101
GLY A 981
TYR A 107
 CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
O  A1058 ( 4.9A)
None
 1.23A 4lxzB-1kcwA:
undetectable		 4lxzB-1kcwA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 HIS A 978
HIS A 103
HIS A 101
GLY A 981
TYR A 107
 CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
O  A1058 ( 4.9A)
None
 1.22A 4lxzC-1kcwA:
undetectable		 4lxzC-1kcwA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 HIS A 980
HIS A 103
HIS A 161
ALA A 166
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
None
 0.69A 4p6sA-1kcwA:
undetectable		 4p6sA-1kcwA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.15A 4qvnV-1kcwA:
undetectable
4qvnb-1kcwA:
undetectable		 4qvnV-1kcwA:
12.54
4qvnb-1kcwA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.14A 4qvnH-1kcwA:
undetectable
4qvnN-1kcwA:
undetectable		 4qvnH-1kcwA:
12.54
4qvnN-1kcwA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 SER A 172
ASP A 128
ASP A 165
 None
 0.83A 4uckA-1kcwA:
undetectable		 4uckA-1kcwA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 9 ILE A 362
PHE A 566
GLY A 533
LEU A 430
LEU A 427
 None
 1.39A 4ze0A-1kcwA:
0.0		 4ze0A-1kcwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 GLY A 638
LEU A 900
PHE A 904
GLY A 873
THR A 682
 None
None
None
None
CU  A1053 ( 4.0A)
 0.98A 4ze1A-1kcwA:
0.0		 4ze1A-1kcwA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A 602
SER A 629
ASN A 632
 CU  A1054 ( 3.4A)
None
None
 0.66A 5cprB-1kcwA:
undetectable		 5cprB-1kcwA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 GLU A  11
TRP A 211
ASN A  92
 None
 0.67A 5dv4A-1kcwA:
1.2		 5dv4A-1kcwA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 GLU A 721
TRP A 910
ASN A 807
 None
 0.82A 5dv4A-1kcwA:
1.2		 5dv4A-1kcwA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 GLY A 638
LEU A 900
PHE A 904
GLY A 873
THR A 682
 None
None
None
None
CU  A1053 ( 4.0A)
 1.06A 5eskA-1kcwA:
undetectable		 5eskA-1kcwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ARG A 845
VAL A 880
TRP A 858
 None
 1.19A 5fvoA-1kcwA:
0.0		 5fvoA-1kcwA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 MET A 968
HIS A 818
GLY A 638
 None
 0.79A 5gwzB-1kcwA:
0.0		 5gwzB-1kcwA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ALA A 656
ASN A 657
LEU A 658
 None
 0.48A 5i1nC-1kcwA:
undetectable		 5i1nC-1kcwA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 ALA A 656
ASN A 657
LEU A 658
 None
 0.47A 5i1pD-1kcwA:
undetectable		 5i1pD-1kcwA:
3.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 HIS A 980
HIS A 103
HIS A 161
ALA A 166
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
None
 0.72A 5i3aA-1kcwA:
undetectable		 5i3aA-1kcwA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 HIS A 980
HIS A 103
HIS A 161
ALA A 166
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
None
 0.75A 5i3aB-1kcwA:
undetectable		 5i3aB-1kcwA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 7 HIS A 980
HIS A 103
HIS A 161
ALA A 166
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
None
 0.73A 5i3bA-1kcwA:
undetectable		 5i3bA-1kcwA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 PHE A 446
LEU A 404
GLY A 533
ILE A 456
 None
 0.78A 5ik1A-1kcwA:
0.0		 5ik1A-1kcwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A1024
PRO A 167
ASP A 165
 None
 0.92A 5l8dB-1kcwA:
0.0		 5l8dB-1kcwA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.18A 5lf7V-1kcwA:
undetectable
5lf7b-1kcwA:
undetectable		 5lf7V-1kcwA:
13.15
5lf7b-1kcwA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.18A 5lf7H-1kcwA:
undetectable
5lf7N-1kcwA:
undetectable		 5lf7H-1kcwA:
13.15
5lf7N-1kcwA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 10 HIS A 637
ASN A 632
LEU A 322
THR A 564
SER A 629
 CU  A1053 ( 3.1A)
None
None
None
None
 1.32A 5m8nA-1kcwA:
undetectable		 5m8nA-1kcwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 10 HIS A1020
HIS A 980
TYR A 107
HIS A 103
HIS A 161
 CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 1.23A 5m8nA-1kcwA:
undetectable		 5m8nA-1kcwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 10 HIS A1020
HIS A 980
TYR A 107
HIS A 103
HIS A 161
 CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 1.36A 5m8nB-1kcwA:
undetectable		 5m8nB-1kcwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 9 HIS A1020
HIS A 980
TYR A 107
HIS A 103
HIS A 161
 CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 1.26A 5m8nC-1kcwA:
0.0		 5m8nC-1kcwA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 101
HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 978
HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.35A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 980
HIS A 978
HIS A 161
HIS A 101
HIS A 103
 CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 1.42A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A1020
HIS A 978
HIS A 163
HIS A 980
HIS A 101
 CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
 1.32A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 101
HIS A 103
HIS A 161
HIS A 978
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
 0.62A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 161
HIS A 101
HIS A 103
HIS A 980
HIS A 978
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.44A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 163
HIS A 161
HIS A1020
HIS A1022
 CU  A1050 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1051 (-3.2A)
 0.77A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1020
HIS A 101
HIS A 163
 CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
 0.39A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1022
HIS A 101
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.73A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.67A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.84A 5mejA-1kcwA:
18.0		 5mejA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 101
HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mewA-1kcwA:
17.9		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 978
HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.34A 5mewA-1kcwA:
17.9		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A1020
HIS A 978
HIS A 163
HIS A 980
HIS A 101
 CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
 1.32A 5mewA-1kcwA:
17.9		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 101
HIS A 103
HIS A 161
HIS A 978
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
 0.62A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 161
HIS A 101
HIS A 103
HIS A 980
HIS A 978
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.44A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 163
HIS A 161
HIS A1020
HIS A1022
 CU  A1050 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1051 (-3.2A)
 0.76A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1020
HIS A 101
HIS A 163
 CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
 0.39A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1022
HIS A 101
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.73A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.68A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.85A 5mewA-1kcwA:
18.0		 5mewA-1kcwA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 101
HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 978
HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.35A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A1020
HIS A 978
HIS A 163
HIS A 980
HIS A 101
 CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
 1.32A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 101
HIS A 103
HIS A 161
HIS A 978
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
 0.63A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 161
HIS A 101
HIS A 103
HIS A 980
HIS A 978
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.43A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 163
HIS A 161
HIS A1020
HIS A1022
 CU  A1050 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1051 (-3.2A)
 0.75A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1020
HIS A 101
HIS A 163
 CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
 0.39A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1022
HIS A 101
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.73A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.69A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.86A 5mhuA-1kcwA:
17.9		 5mhuA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 101
HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A 978
HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.36A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 5 HIS A1020
HIS A 978
HIS A 163
HIS A 980
HIS A 101
 CU  A1050 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
 1.32A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 101
HIS A 103
HIS A 161
HIS A 978
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
 0.64A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 6 HIS A 161
HIS A 101
HIS A 103
HIS A 980
HIS A 978
 CU  A1051 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 ( 3.2A)
 1.43A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 163
HIS A 161
HIS A1020
HIS A1022
 CU  A1050 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1051 (-3.2A)
 0.75A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1020
HIS A 101
HIS A 163
 CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1052 (-3.2A)
CU  A1050 (-3.3A)
 0.38A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 HIS A 978
HIS A1022
HIS A 101
HIS A 161
 CU  A1052 ( 3.2A)
CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.72A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.70A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.87A 5mhvA-1kcwA:
17.9		 5mhvA-1kcwA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.49A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.36A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.72A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.81A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.70A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.87A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 5mhwA-1kcwA:
17.9		 5mhwA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.49A 5mhxA-1kcwA:
17.9		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.37A 5mhxA-1kcwA:
17.9		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.72A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.70A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.87A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 5mhxA-1kcwA:
18.0		 5mhxA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mhyA-1kcwA:
9.9		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.37A 5mhyA-1kcwA:
9.9		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.72A 5mhyA-1kcwA:
9.9		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mhyA-1kcwA:
9.9		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.81A 5mhyA-1kcwA:
9.9		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.70A 5mhyA-1kcwA:
8.8		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mhyA-1kcwA:
8.8		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5mhyA-1kcwA:
8.8		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 5mhyA-1kcwA:
8.8		 5mhyA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.38A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.72A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.89A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 5mhzA-1kcwA:
18.0		 5mhzA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mi1A-1kcwA:
18.0		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.38A 5mi1A-1kcwA:
18.0		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.71A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 980
HIS A 103
HIS A 161
HIS A 163
 CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
 1.32A 5mi1A-1kcwA:
17.9		 5mi1A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.50A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.38A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.72A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.71A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5mi2A-1kcwA:
18.0		 5mi2A-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.39A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.71A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5miaA-1kcwA:
17.9		 5miaA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.39A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.71A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5mibA-1kcwA:
17.9		 5mibA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.39A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.81A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.71A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5micA-1kcwA:
17.9		 5micA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5midA-1kcwA:
17.9		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.39A 5midA-1kcwA:
17.9		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.72A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.89A 5midA-1kcwA:
9.2		 5midA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 163
HIS A 978
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.51A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A1022
HIS A 101
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.39A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.73A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.97A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.80A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.72A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.30A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.89A 5mieA-1kcwA:
17.9		 5mieA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A 163
HIS A 980
HIS A1020
 CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1050 (-3.2A)
 0.59A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A1022
HIS A 103
HIS A 161
 CU  A1051 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.28A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 101
HIS A 103
HIS A 161
HIS A1022
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
CU  A1051 (-3.2A)
 0.74A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A 163
HIS A 101
HIS A 161
HIS A 103
 CU  A1050 (-3.3A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1051 (-3.3A)
 0.96A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 HIS A1022
HIS A 978
HIS A1020
HIS A 980
 CU  A1051 (-3.2A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
 0.79A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 101
HIS A 103
HIS A 978
HIS A 980
 CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
 0.72A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 161
HIS A 163
HIS A 980
HIS A 103
 CU  A1051 (-3.3A)
CU  A1050 (-3.3A)
CU  A1050 (-3.0A)
CU  A1051 (-3.3A)
 1.29A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 978
HIS A 980
HIS A 101
HIS A 103
 CU  A1052 ( 3.2A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 0.88A 5migA-1kcwA:
17.9		 5migA-1kcwA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 THR A1024
PRO A 167
ASP A 165
 None
 0.92A 5mwuB-1kcwA:
0.0		 5mwuB-1kcwA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 HIS A 103
HIS A 980
HIS A 163
 CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1050 (-3.3A)
 0.97A 5oexA-1kcwA:
undetectable		 5oexA-1kcwA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		3 / 3 TRP A 364
MET A 608
ASN A 611
 None
 1.02A 5uc1A-1kcwA:
undetectable		 5uc1A-1kcwA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 PHE A1000
PRO A1001
GLY A1002
THR A1003
 None
 0.54A 5x24A-1kcwA:
0.0		 5x24A-1kcwA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 MET A 269
TYR A 160
GLY A 176
GLY A  75
 None
 0.93A 5x7pA-1kcwA:
1.2		 5x7pA-1kcwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 MET A 968
TYR A 860
GLY A 876
GLY A 790
 None
 1.16A 5x7pA-1kcwA:
1.2		 5x7pA-1kcwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 5 TYR A 520
TYR A 521
GLY A 536
GLY A 431
 None
 1.14A 5x7pA-1kcwA:
1.2		 5x7pA-1kcwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 6 MET A 269
TYR A 160
GLY A 176
GLY A  75
 None
 0.97A 5x7pB-1kcwA:
0.5		 5x7pB-1kcwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.24A 5z0fA-1kcwA:
undetectable
5z0fB-1kcwA:
0.0		 5z0fA-1kcwA:
6.24
5z0fB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.19A 5z0gA-1kcwA:
undetectable
5z0gB-1kcwA:
0.0		 5z0gA-1kcwA:
6.24
5z0gB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.19A 5z0hA-1kcwA:
undetectable
5z0hB-1kcwA:
0.0		 5z0hA-1kcwA:
6.24
5z0hB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.18A 5z0iA-1kcwA:
undetectable
5z0iB-1kcwA:
0.0		 5z0iA-1kcwA:
6.24
5z0iB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.18A 5z0jA-1kcwA:
undetectable
5z0jB-1kcwA:
undetectable		 5z0jA-1kcwA:
6.24
5z0jB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.15A 5z0kA-1kcwA:
undetectable
5z0kB-1kcwA:
0.0		 5z0kA-1kcwA:
6.24
5z0kB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.20A 5z0lA-1kcwA:
undetectable
5z0lB-1kcwA:
0.0		 5z0lA-1kcwA:
6.24
5z0lB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 11 HIS A 161
HIS A1020
HIS A 980
ASP A 118
PRO A 117
 CU  A1051 (-3.3A)
CU  A1050 (-3.2A)
CU  A1050 (-3.0A)
None
None
 1.29A 5z0mA-1kcwA:
undetectable
5z0mB-1kcwA:
0.0		 5z0mA-1kcwA:
6.34
5z0mB-1kcwA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 103
HIS A 980
HIS A 101
HIS A 161
 CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 1.08A 5zrdC-1kcwA:
undetectable		 5zrdC-1kcwA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 HIS A 103
HIS A 980
HIS A 101
HIS A 161
 CU  A1051 (-3.3A)
CU  A1050 (-3.0A)
CU  A1052 (-3.2A)
CU  A1051 (-3.3A)
 1.10A 5zrdD-1kcwA:
undetectable		 5zrdD-1kcwA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A1033
ILE A 942
PHE A 901
PHE A 897
LEU A 895
 None
 1.40A 6a93A-1kcwA:
undetectable		 6a93A-1kcwA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 GLY A 643
GLY A 819
SER A 825
PHE A 676
ASP A 671
 None
 1.30A 6clxA-1kcwA:
undetectable		 6clxA-1kcwA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		4 / 4 MET A 269
GLY A 268
HIS A 276
GLY A 270
 None
None
CU  A1049 ( 3.1A)
None
 1.37A 6fgdA-1kcwA:
undetectable		 6fgdA-1kcwA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.16A 6hwdV-1kcwA:
undetectable
6hwdb-1kcwA:
undetectable		 6hwdV-1kcwA:
6.28
6hwdb-1kcwA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 1kcw CERULOPLASMIN
(Homo
sapiens) 		5 / 12 THR A 582
THR A 583
THR A 394
ALA A 584
GLY A 398
 None
 1.16A 6hwdH-1kcwA:
undetectable
6hwdN-1kcwA:
undetectable		 6hwdH-1kcwA:
6.28
6hwdN-1kcwA:
5.69