SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 1kec PENICILLIN ACYLASE
ALPHA SUBUNIT
(Escherichia
coli) 		4 / 4 GLY A  30
TYR A  29
GLY A  99
ASP A  98
 None
 1.35A 3kl3A-1kecA:
undetectable		 3kl3A-1kecA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 1kec PENICILLIN ACYLASE
ALPHA SUBUNIT
(Escherichia
coli) 		3 / 3 THR A 208
ASN A 205
SER A 206
 None
 0.78A 4tvtA-1kecA:
undetectable		 4tvtA-1kecA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 1kec PENICILLIN ACYLASE
ALPHA SUBUNIT
(Escherichia
coli) 		3 / 3 THR A 125
GLU A 112
ASN A 108
 None
 0.87A 6nj9K-1kecA:
undetectable		 6nj9K-1kecA:
20.11