SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1keh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_C_ACTC3007_0
(BETA-CARBONIC
ANHYDRASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 6 ASP A 136
VAL A 138
GLY A 134
TYR A  93
None
1.27A 1ekjC-1kehA:
undetectable
1ekjD-1kehA:
undetectable
1ekjC-1kehA:
15.87
1ekjD-1kehA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
6 / 12 ILE A 111
ALA A 115
ALA A 113
GLN A 116
LEU A 130
VAL A 137
None
1.39A 1fbyB-1kehA:
undetectable
1fbyB-1kehA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
6 / 12 ILE A 111
ALA A 115
ALA A 113
GLN A 116
LEU A 130
VAL A 137
None
1.38A 1fm6A-1kehA:
undetectable
1fm6A-1kehA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 11 GLU A 204
LEU A 641
ARG A 668
GLY A 623
HIS A 192
None
1.26A 1g50C-1kehA:
0.0
1g50C-1kehA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 6 ALA A 514
ARG A 584
LEU A 515
TRP A 609
None
1.16A 1gahA-1kehA:
undetectable
1gahA-1kehA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ALA A 351
VAL A 175
TRP A 173
None
1.01A 1tkqA-1kehA:
undetectable
1tkqA-1kehA:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 ARG A 637
ASN A 230
HIS A 206
VAL A 636
None
1.36A 1u1jA-1kehA:
undetectable
1u1jA-1kehA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 LEU A 671
LEU A 672
ARG A 353
TYR A 639
None
1.23A 2hc4A-1kehA:
undetectable
2hc4A-1kehA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 12 LEU A 601
GLU A 518
ARG A 522
GLY A 623
HIS A 192
None
1.28A 2j7xA-1kehA:
0.0
2j7xA-1kehA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ARG A 637
VAL A 175
THR A 180
None
0.85A 2nnkA-1kehA:
undetectable
2nnkA-1kehA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 5 ALA A 564
ALA A 485
ALA A 484
VAL A 551
None
0.94A 2nyrB-1kehA:
undetectable
2nyrB-1kehA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ASP A 589
THR A 619
PRO A 620
None
0.53A 2pynB-1kehA:
undetectable
2pynB-1kehA:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ASP A 589
THR A 619
PRO A 620
None
0.47A 2q64B-1kehA:
undetectable
2q64B-1kehA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ASP A 589
THR A 619
PRO A 620
None
0.56A 2qakB-1kehA:
undetectable
2qakB-1kehA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 THR A 619
PRO A 620
VAL A 621
SER A 610
None
1.07A 2v41E-1kehA:
undetectable
2v41F-1kehA:
undetectable
2v41E-1kehA:
14.37
2v41F-1kehA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 ARG A 562
GLU A 492
ALA A 485
ALA A 497
None
1.07A 2zgwA-1kehA:
0.0
2zgwA-1kehA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 4 ILE A 214
ARG A 340
ILE A 326
THR A 209
None
1.28A 3ia4C-1kehA:
undetectable
3ia4C-1kehA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ARG A 637
VAL A 175
THR A 180
None
0.85A 3k4vA-1kehA:
0.0
3k4vA-1kehA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.91A 3nbqB-1kehA:
0.0
3nbqB-1kehA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.89A 3nbqC-1kehA:
0.0
3nbqC-1kehA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ARG A 637
VAL A 175
THR A 180
None
0.81A 3ndtA-1kehA:
0.0
3ndtA-1kehA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_2
(PROTEASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ARG A 637
VAL A 175
THR A 180
None
0.81A 3pwrA-1kehA:
undetectable
3pwrA-1kehA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 ALA A  89
GLN A  90
ASP A 136
SER A 133
None
0.91A 3qj7A-1kehA:
undetectable
3qj7D-1kehA:
0.0
3qj7A-1kehA:
16.09
3qj7D-1kehA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 5 ALA A 665
GLU A 624
ALA A 596
MET A 585
None
1.45A 3r9tC-1kehA:
undetectable
3r9tC-1kehA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ASP A 589
THR A 619
PRO A 620
None
0.39A 3tkgD-1kehA:
undetectable
3tkgD-1kehA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 11 GLU A 204
LEU A 641
ARG A 668
GLY A 623
HIS A 192
None
1.24A 3uudA-1kehA:
undetectable
3uudA-1kehA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 12 SER A 412
ASN A 411
PRO A 544
VAL A 448
GLN A 410
None
1.19A 4b3aA-1kehA:
0.0
4b3aA-1kehA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 ASN A 646
GLY A  26
VAL A  27
ILE A  20
None
0.95A 4fglD-1kehA:
undetectable
4fglD-1kehA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 ASN A 646
VAL A  27
ILE A  30
PHE A 687
None
0.88A 4fglC-1kehA:
undetectable
4fglC-1kehA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 10 ALA A 501
LEU A 500
ILE A 565
ALA A 564
ALA A 557
None
0.98A 4j14A-1kehA:
0.0
4j14A-1kehA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 10 LEU A 459
ALA A 665
PHE A 467
GLU A 460
LEU A 188
None
1.47A 4la0A-1kehA:
0.2
4la0A-1kehA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 5 THR A 625
PRO A 191
PHE A 667
ASN A 190
None
1.46A 4mf6A-1kehA:
undetectable
4mf6A-1kehA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 ASP A 613
LYS A 571
LEU A 515
None
0.82A 4ptjA-1kehA:
0.0
4ptjA-1kehA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 GLU A 683
THR A 653
HIS A 654
None
0.78A 4q15A-1kehA:
undetectable
4q15A-1kehA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 GLU A 683
THR A 653
HIS A 654
None
0.79A 4q15B-1kehA:
0.0
4q15B-1kehA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.92A 4txnA-1kehA:
undetectable
4txnA-1kehA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.94A 4txnB-1kehA:
undetectable
4txnB-1kehA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.93A 4txnC-1kehA:
undetectable
4txnC-1kehA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 THR A 218
GLY A 216
GLN A 189
ILE A 326
None
0.95A 4txnD-1kehA:
undetectable
4txnD-1kehA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 11 GLU A 204
LEU A 641
ARG A 668
GLY A 623
HIS A 192
None
1.24A 5dxgB-1kehA:
0.0
5dxgB-1kehA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 7 VAL A 493
ALA A 497
VAL A 558
ARG A 562
None
0.80A 5fpdB-1kehA:
undetectable
5fpdB-1kehA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 12 LEU A 499
LEU A 601
LEU A 500
THR A 568
ALA A 564
None
1.07A 5ienB-1kehA:
undetectable
5ienB-1kehA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 12 LEU A 641
LEU A 465
PHE A 467
THR A 458
LEU A 457
None
1.30A 5tiwA-1kehA:
undetectable
5tiwA-1kehA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
3 / 3 GLU A 370
ARG A 386
TYR A 387
None
0.63A 5trqB-1kehA:
0.0
5trqB-1kehA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
5 / 12 TYR A  42
PHE A 687
ILE A  20
PHE A 107
GLY A  32
None
1.31A 5v5zA-1kehA:
undetectable
5v5zA-1kehA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 8 GLN A  46
GLY A  43
ILE A  30
TRP A  22
None
1.05A 5vlmD-1kehA:
0.0
5vlmD-1kehA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 6 PHE A 524
ARG A 522
ALA A 557
GLN A 527
None
1.01A 6b89B-1kehA:
undetectable
6b89B-1kehA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)
1keh PRECURSOR OF
CEPHALOSPORIN
ACYLASE

(Brevundimonas
diminuta)
4 / 5 VAL A 310
PRO A 316
MET A 318
VAL A 138
None
1.34A 6ekzA-1kehA:
undetectable
6ekzA-1kehA:
10.27