SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 ARG A 335
ARG A 443
ARG A 508
 None
 1.11A 1l7hA-1kejA:
undetectable		 1l7hA-1kejA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		4 / 7 PHE A 456
LEU A 460
LEU A 472
GLU A 504
 None
 1.04A 2jn3A-1kejA:
undetectable		 2jn3A-1kejA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 LEU A 347
ARG A 443
ILE A 348
 None
 0.58A 2xn5B-1kejA:
0.0		 2xn5B-1kejA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		4 / 7 LEU A 500
PHE A 495
ARG A 336
THR A 159
 None
None
DAD  A 601 (-3.2A)
None
 0.99A 3ag4N-1kejA:
0.4
3ag4W-1kejA:
0.0		 3ag4N-1kejA:
19.85
3ag4W-1kejA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 ASP A 343
ARG A 432
ARG A 336
 CO  A 701 (-2.5A)
None
DAD  A 601 (-3.2A)
 0.89A 3k37A-1kejA:
undetectable		 3k37A-1kejA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 LYS A 199
THR A 169
ILE A 174
 None
 0.89A 4e0fB-1kejA:
0.0		 4e0fB-1kejA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		4 / 7 LEU A 406
LEU A 408
ALA A 318
LEU A 435
 None
 0.61A 4z90F-1kejA:
0.0
4z90G-1kejA:
0.0
4z90H-1kejA:
0.0
4z90J-1kejA:
0.0		 4z90F-1kejA:
19.79
4z90G-1kejA:
19.79
4z90H-1kejA:
19.79
4z90J-1kejA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		4 / 8 LEU A 500
PHE A 495
ARG A 336
THR A 159
 None
None
DAD  A 601 (-3.2A)
None
 0.89A 5xdxN-1kejA:
0.0
5xdxW-1kejA:
0.0		 5xdxN-1kejA:
19.85
5xdxW-1kejA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		4 / 8 LEU A 500
PHE A 495
ARG A 336
THR A 159
 None
None
DAD  A 601 (-3.2A)
None
 0.89A 5zcpN-1kejA:
0.0
5zcpW-1kejA:
0.0		 5zcpN-1kejA:
19.85
5zcpW-1kejA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 LEU A 460
LEU A 448
ARG A 508
 None
 0.52A 6fgcA-1kejA:
1.2		 6fgcA-1kejA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM
(Mus
musculus) 		3 / 3 LEU A 460
LEU A 448
ARG A 508
 None
 0.51A 6fgdA-1kejA:
2.0		 6fgdA-1kejA:
21.29