SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 LEU A 368
LYS A 367
LEU A 381
ALA A 348
None
0.73A 1e7cA-1kfiA:
undetectable
1e7cA-1kfiA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 6 GLU A 392
THR A 371
ALA A 348
LEU A 389
None
1.13A 1etb2-1kfiA:
0.0
1etb2-1kfiA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 VAL A  92
TYR A 106
TYR A 245
VAL A 241
None
0.82A 1fduB-1kfiA:
undetectable
1fduB-1kfiA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_A_115A2_2
(HMG-COA REDUCTASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 GLU A 112
HIS A 105
LEU A 212
LEU A 216
None
0.83A 1hwiB-1kfiA:
4.8
1hwiB-1kfiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 GLU A 112
HIS A 105
LEU A 212
LEU A 216
None
0.81A 1hwiD-1kfiA:
4.7
1hwiD-1kfiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_1
(HMG-COA REDUCTASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 GLU A 112
HIS A 105
LEU A 212
LEU A 216
None
0.81A 1hwiC-1kfiA:
4.2
1hwiC-1kfiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 5 LEU A 415
VAL A 411
ALA A 311
CYH A 307
None
0.91A 1mz9C-1kfiA:
undetectable
1mz9C-1kfiA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 5 LEU A 415
VAL A 411
ALA A 311
CYH A 307
None
1.05A 1mz9D-1kfiA:
0.0
1mz9D-1kfiA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 ILE A 178
LEU A 180
MET A  98
GLY A  64
None
0.78A 1os6A-1kfiA:
undetectable
1os6A-1kfiA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 VAL A 170
ILE A 121
VAL A  63
ILE A  75
ILE A 178
None
1.30A 1r5lA-1kfiA:
undetectable
1r5lA-1kfiA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 THR A 124
VAL A 241
GLY A 240
ASP A 312
None
None
None
ZN  A 700 ( 2.4A)
0.89A 2a1mA-1kfiA:
0.0
2a1mA-1kfiA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 10 SER A  45
PHE A  42
TYR A  38
GLY A  22
TYR A 158
None
1.43A 2b8jB-1kfiA:
1.3
2b8jB-1kfiA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
3 / 3 THR A 145
ASP A 490
SER A 497
None
0.84A 2nxeA-1kfiA:
undetectable
2nxeA-1kfiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
3 / 3 THR A 145
ASP A 490
SER A 497
None
0.82A 2nxeB-1kfiA:
undetectable
2nxeB-1kfiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 MET A 213
GLY A 240
PHE A 235
PHE A 250
None
0.91A 2qwxA-1kfiA:
undetectable
2qwxB-1kfiA:
undetectable
2qwxA-1kfiA:
16.58
2qwxB-1kfiA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 ARG A  27
HIS A 274
THR A 525
GLN A 454
None
1.17A 2vxaF-1kfiA:
0.0
2vxaG-1kfiA:
0.0
2vxaI-1kfiA:
0.0
2vxaF-1kfiA:
8.08
2vxaG-1kfiA:
8.08
2vxaI-1kfiA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 11 SER A 354
LEU A 344
LEU A 389
SER A 326
LEU A 329
None
1.04A 2xn5A-1kfiA:
0.5
2xn5A-1kfiA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 TYR A 473
PHE A 474
PHE A 506
ILE A 556
None
1.22A 2zseA-1kfiA:
0.0
2zseA-1kfiA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 PRO A 325
THR A 324
LEU A 279
ILE A 291
LEU A 285
None
1.18A 3a50E-1kfiA:
undetectable
3a50E-1kfiA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 GLY A  65
GLY A 243
GLY A 240
GLY A  67
PHE A 250
None
0.96A 3eluA-1kfiA:
undetectable
3eluA-1kfiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
6 / 12 GLY A  67
GLY A  64
GLY A  96
VAL A  43
PHE A  42
ILE A 139
None
1.30A 3elwA-1kfiA:
undetectable
3elwA-1kfiA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
3 / 3 SER A  45
GLN A  44
PHE A  47
None
0.82A 3g4lC-1kfiA:
0.0
3g4lC-1kfiA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
3 / 3 ILE A 118
PHE A  47
HIS A  91
None
0.75A 3h0aA-1kfiA:
0.0
3h0aA-1kfiA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 GLU A  54
VAL A  90
GLY A 119
PHE A 153
ILE A 118
None
1.20A 3k13A-1kfiA:
undetectable
3k13A-1kfiA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 ILE A 316
TRP A 409
SER A 328
ILE A 332
None
1.07A 3sfeB-1kfiA:
undetectable
3sfeC-1kfiA:
0.3
3sfeB-1kfiA:
19.11
3sfeC-1kfiA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 PHE A 250
ALA A 305
PHE A 235
ALA A 410
None
0.86A 3t3sD-1kfiA:
undetectable
3t3sD-1kfiA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 THR A 205
GLY A  65
GLY A  93
ALA A  95
GLY A  67
None
0.96A 3tegA-1kfiA:
3.6
3tegA-1kfiA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 4 ASP A 310
ASP A  66
GLY A  64
THR A 205
ZN  A 700 ( 2.3A)
None
None
None
1.36A 3tl9B-1kfiA:
undetectable
3tl9B-1kfiA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 LEU A 329
LEU A 357
ILE A 387
MET A 382
None
0.98A 3u5jA-1kfiA:
undetectable
3u5jA-1kfiA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 PHE A  62
VAL A  63
ILE A 121
ALA A 149
None
0.93A 4eyzA-1kfiA:
0.4
4eyzA-1kfiA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 PHE A  62
VAL A  63
ILE A 121
ALA A 149
None
0.95A 4eyzB-1kfiA:
0.5
4eyzB-1kfiA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 ILE A 178
LEU A 180
MET A  98
GLY A  64
None
0.80A 4hajA-1kfiA:
undetectable
4hajA-1kfiA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 ILE A 178
LEU A 180
MET A  98
GLY A  64
None
0.81A 4hb6A-1kfiA:
undetectable
4hb6A-1kfiA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 ILE A 178
LEU A 180
MET A  98
GLY A  64
None
0.84A 4hc3A-1kfiA:
undetectable
4hc3A-1kfiA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K88_A_HFGA602_0
(PROLINE--TRNA LIGASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 12 GLU A 151
PRO A 372
THR A 373
GLU A 392
SER A 394
None
None
SO4  A 603 ( 4.3A)
None
None
1.47A 4k88A-1kfiA:
2.2
4k88A-1kfiA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 5 PRO A 266
GLY A  67
ASP A 284
ASP A 269
None
1.08A 4n48B-1kfiA:
undetectable
4n48B-1kfiA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 9 VAL A 241
ILE A 316
VAL A 411
ALA A 410
ALA A 311
None
1.27A 4oqrA-1kfiA:
0.0
4oqrA-1kfiA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
3 / 3 ARG A 449
GLU A 392
TYR A 529
None
0.99A 4r29D-1kfiA:
0.0
4r29D-1kfiA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 11 SER A 103
LEU A  97
ALA A  95
VAL A  92
ILE A 121
None
1.17A 4uuuB-1kfiA:
0.0
4uuuB-1kfiA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 4 ILE A 107
ASN A 142
ILE A 121
VAL A  63
None
1.29A 4uy87-1kfiA:
undetectable
4uy87-1kfiA:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 10 LEU A 317
LEU A 289
GLY A 304
ASP A 236
ILE A 291
None
1.09A 4xj7C-1kfiA:
undetectable
4xj7D-1kfiA:
undetectable
4xj7C-1kfiA:
18.78
4xj7D-1kfiA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
5 / 10 SER A 354
LEU A 344
LEU A 389
SER A 326
LEU A 329
None
1.02A 4yiaA-1kfiA:
0.5
4yiaA-1kfiA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_1
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 SER A 497
TYR A 488
LYS A 376
PHE A 377
None
1.21A 5dlvB-1kfiA:
1.4
5dlvB-1kfiA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 HIS A 401
LEU A 212
LEU A 216
THR A 416
None
0.97A 5hs6A-1kfiA:
undetectable
5hs6A-1kfiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 6 GLY A 115
ASP A 208
ILE A 402
ARG A 108
None
0.99A 5iwuA-1kfiA:
undetectable
5iwuA-1kfiA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 8 ASP A 312
PRO A 101
TYR A 209
ASN A 314
ZN  A 700 ( 2.4A)
None
None
None
1.08A 5l1fA-1kfiA:
undetectable
5l1fB-1kfiA:
2.1
5l1fA-1kfiA:
21.24
5l1fB-1kfiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 7 ILE A 107
LEU A  50
PHE A  47
THR A 154
None
1.00A 5vc0A-1kfiA:
0.0
5vc0A-1kfiA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)
1kfi PHOSPHOGLUCOMUTASE 1
(Paramecium
tetraurelia)
4 / 5 ASN A 179
GLN A 182
ASP A 181
ARG A  72
None
1.30A 5w4zA-1kfiA:
undetectable
5w4zA-1kfiA:
10.85