SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ALA A 335
VAL A 338
TRP A 378
 None
 0.82A 1av2A-1kfwA:
undetectable
1av2B-1kfwA:
undetectable		 1av2A-1kfwA:
3.19
1av2B-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 378
ALA A 335
VAL A 338
 None
 0.85A 1av2C-1kfwA:
undetectable
1av2D-1kfwA:
undetectable		 1av2C-1kfwA:
3.19
1av2D-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 9 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
 0.83A 1e9lA-1kfwA:
43.8		 1e9lA-1kfwA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ALA A 335
VAL A 338
TRP A 378
 None
 0.91A 1gmkA-1kfwA:
undetectable
1gmkB-1kfwA:
undetectable		 1gmkA-1kfwA:
3.19
1gmkB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 4 VAL A 338
TRP A 332
TRP A 378
 None
 1.27A 1gmkA-1kfwA:
undetectable
1gmkB-1kfwA:
undetectable		 1gmkA-1kfwA:
3.19
1gmkB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ALA A 335
VAL A 338
TRP A 378
 None
 0.96A 1gmkC-1kfwA:
undetectable
1gmkD-1kfwA:
undetectable		 1gmkC-1kfwA:
3.19
1gmkD-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 VAL A  29
SER A  54
ILE A 131
LEU A 117
 None
 0.89A 1igxA-1kfwA:
undetectable		 1igxA-1kfwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 PHE A 142
SER A 158
PHE A  66
GLY A  56
LEU A 218
 None
None
GOL  A 531 (-2.8A)
GOL  A 531 ( 4.5A)
None
 1.13A 1kglA-1kfwA:
0.0		 1kglA-1kfwA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 195
THR A 196
ALA A 212
GLY A 204
SER A 143
 None
 1.22A 1nbiD-1kfwA:
undetectable		 1nbiD-1kfwA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.87A 1os6A-1kfwA:
undetectable		 1os6A-1kfwA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_B_NOVB2300_1
(TOPOISOMERASE IV
SUBUNIT B)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 SER A 239
ASP A 188
PRO A 243
ALA A 244
ILE A 268
 None
 1.21A 1s14B-1kfwA:
undetectable		 1s14B-1kfwA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ALA A 335
VAL A 338
TRP A 378
 None
 0.84A 1w5uA-1kfwA:
undetectable
1w5uB-1kfwA:
undetectable		 1w5uA-1kfwA:
3.19
1w5uB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 378
ALA A 335
VAL A 338
 None
 0.85A 1w5uA-1kfwA:
undetectable
1w5uB-1kfwA:
undetectable		 1w5uA-1kfwA:
3.19
1w5uB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 PRO A 437
TYR A 400
ILE A 401
VAL A 308
LEU A 288
 None
 1.29A 1z9hA-1kfwA:
0.0		 1z9hA-1kfwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 PRO A 437
TYR A 400
ILE A 401
VAL A 308
LEU A 288
 None
 1.30A 1z9hB-1kfwA:
0.0		 1z9hB-1kfwA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 PRO A 437
TYR A 400
ILE A 401
VAL A 308
LEU A 288
 None
 1.29A 1z9hC-1kfwA:
0.0		 1z9hC-1kfwA:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 11 TYR A  23
PHE A  55
GLY A 135
ASP A 190
GLU A 192
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.35A 2a3aA-1kfwA:
46.0		 2a3aA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		8 / 11 TYR A  23
PHE A  55
GLY A 135
TRP A 136
ASP A 190
GLU A 192
TYR A 271
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.55A 2a3aA-1kfwA:
46.0		 2a3aA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_B_TEPB2433_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 9 PHE A  55
GLY A 135
GLU A 192
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.45A 2a3aB-1kfwA:
46.2		 2a3aB-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 11 TYR A  23
PHE A  55
GLY A 135
ASP A 190
GLU A 192
TYR A 271
TRP A 412
 None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.67A 2a3bA-1kfwA:
46.1		 2a3bA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		8 / 11 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.38A 2a3bA-1kfwA:
46.1		 2a3bA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		8 / 11 TYR A  23
PHE A  55
GLY A 135
TRP A 136
ASP A 190
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.7A)
None
None
 0.59A 2a3bA-1kfwA:
46.1		 2a3bA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 11 TYR A  23
PHE A  55
GLY A 135
TRP A 136
ASP A 190
GLU A 192
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.9A)
None
 0.80A 2a3bA-1kfwA:
46.1		 2a3bA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 10 PHE A  55
GLY A 135
ASP A 190
GLU A 192
TYR A 271
TYR A 328
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
None
 0.66A 2a3bB-1kfwA:
46.1		 2a3bB-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 10 PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.40A 2a3bB-1kfwA:
46.1		 2a3bB-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		8 / 12 TYR A  23
TRP A  27
PHE A  55
GLY A 135
ASP A 190
GLU A 192
TYR A 271
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.65A 2a3cA-1kfwA:
45.9		 2a3cA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 12 TYR A  23
TRP A  27
PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.39A 2a3cA-1kfwA:
45.9		 2a3cA-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 12 TRP A  27
PHE A  55
GLY A 135
THR A 137
ASP A 190
GLU A 192
TYR A 271
TYR A 328
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
None
 0.64A 2a3cB-1kfwA:
46.1		 2a3cB-1kfwA:
31.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 12 TRP A  27
PHE A  55
GLY A 135
THR A 137
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.47A 2a3cB-1kfwA:
46.1		 2a3cB-1kfwA:
31.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ARG A 431
VAL A 438
GLY A 322
 None
 0.53A 2avvE-1kfwA:
undetectable		 2avvE-1kfwA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ALA A 335
VAL A 338
TRP A 378
 None
 0.85A 2izqA-1kfwA:
undetectable
2izqB-1kfwA:
undetectable		 2izqA-1kfwA:
3.19
2izqB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 378
ALA A 335
VAL A 338
 None
 0.83A 2izqC-1kfwA:
undetectable
2izqD-1kfwA:
undetectable		 2izqC-1kfwA:
3.19
2izqD-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 TYR A  23
PHE A 241
ASP A 190
GLU A 192
 None
GOL  A 530 (-4.8A)
None
GOL  A 530 (-3.9A)
 0.96A 2qebA-1kfwA:
0.0		 2qebA-1kfwA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 TYR A  23
PHE A 241
ASP A 190
GLU A 192
 None
GOL  A 530 (-4.8A)
None
GOL  A 530 (-3.9A)
 1.00A 2qebB-1kfwA:
0.0		 2qebB-1kfwA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 GLY A 420
THR A  44
GLN A  38
PHE A  34
 None
 1.14A 2qx4A-1kfwA:
undetectable
2qx4B-1kfwA:
undetectable		 2qx4A-1kfwA:
20.32
2qx4B-1kfwA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 9 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
None
 0.91A 2uy4A-1kfwA:
19.3		 2uy4A-1kfwA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 9 TYR A  23
PHE A  55
GLY A 135
GLU A 192
TYR A 271
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.53A 2uy4A-1kfwA:
19.3		 2uy4A-1kfwA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 11 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
None
 1.04A 2xtkA-1kfwA:
20.9		 2xtkA-1kfwA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 11 TYR A  23
PHE A  55
GLY A 135
GLU A 192
TYR A 271
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.80A 2xtkA-1kfwA:
20.9		 2xtkA-1kfwA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 10 TYR A  23
PHE A  55
GLY A 135
ASP A 190
TYR A 271
TRP A 412
 None
None
None
None
GOL  A 530 (-4.8A)
None
 0.98A 2xtkB-1kfwA:
20.9		 2xtkB-1kfwA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 10 TYR A  23
PHE A  55
GLY A 135
GLU A 192
TYR A 271
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
None
 0.66A 2xtkB-1kfwA:
20.9		 2xtkB-1kfwA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 GLN A 320
PHE A 265
LEU A 218
PHE A 214
 None
 1.39A 3ablC-1kfwA:
0.0
3ablJ-1kfwA:
0.0		 3ablC-1kfwA:
19.52
3ablJ-1kfwA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 6 TRP A 136
ASP A 272
TRP A 277
ARG A 330
 None
GOL  A 530 (-3.7A)
None
None
 0.46A 3arqA-1kfwA:
40.0		 3arqA-1kfwA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 TRP A 136
ASP A 272
TRP A 277
ARG A 330
 None
GOL  A 530 (-3.7A)
None
None
 0.42A 3arrA-1kfwA:
39.8		 3arrA-1kfwA:
26.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 THR A 137
GLU A 192
GLY A 199
GLU A 353
 None
GOL  A 530 (-3.9A)
None
None
 0.62A 3aruA-1kfwA:
39.6		 3aruA-1kfwA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FGR_B_ACTB21_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2 40 KDA FORM)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 4 ARG A 296
ASP A 291
ASP A 294
PRO A 295
 None
 1.00A 3fgrB-1kfwA:
0.0		 3fgrB-1kfwA:
20.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		10 / 11 TYR A  23
PHE A  55
GLY A 135
TRP A 136
ASP A 190
GLU A 192
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.52A 3g6mA-1kfwA:
46.7		 3g6mA-1kfwA:
33.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 4 ARG A 379
ASP A 272
GLY A 324
THR A 393
 None
GOL  A 530 (-3.7A)
None
None
 1.48A 3k4vB-1kfwA:
0.0		 3k4vB-1kfwA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 ARG A 296
ASP A 294
ASP A 291
TRP A 341
 None
 1.39A 3kivA-1kfwA:
undetectable		 3kivA-1kfwA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 166
GLY A 182
ALA A 177
GLY A 176
LEU A 110
 None
 0.83A 3ku1A-1kfwA:
undetectable		 3ku1A-1kfwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 166
GLY A 182
ALA A 177
GLY A 176
LEU A 110
 None
 0.86A 3ku1C-1kfwA:
undetectable		 3ku1C-1kfwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 378
ALA A 335
VAL A 338
 None
 0.71A 3l8lA-1kfwA:
undetectable
3l8lB-1kfwA:
undetectable		 3l8lA-1kfwA:
3.19
3l8lB-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 378
ALA A 335
VAL A 338
 None
 0.80A 3l8lC-1kfwA:
undetectable
3l8lD-1kfwA:
undetectable		 3l8lC-1kfwA:
3.19
3l8lD-1kfwA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 324
GLY A 409
ASN A  20
ALA A 326
THR A 393
 None
 1.19A 3mteA-1kfwA:
undetectable		 3mteA-1kfwA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 ALA A  36
GLN A 116
LEU A 117
SER A 100
 None
 1.01A 3qj7A-1kfwA:
undetectable
3qj7D-1kfwA:
undetectable		 3qj7A-1kfwA:
19.53
3qj7D-1kfwA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.83A 3selX-1kfwA:
undetectable		 3selX-1kfwA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 6 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.78A 3sj1X-1kfwA:
0.0		 3sj1X-1kfwA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 195
ILE A  58
GLY A 204
ALA A 146
ALA A 145
 None
 0.94A 3sudC-1kfwA:
undetectable		 3sudC-1kfwA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 195
ILE A  58
GLY A 204
ALA A 146
ALA A 145
 None
 0.88A 3sueA-1kfwA:
undetectable		 3sueA-1kfwA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 ASP A 389
GLY A 283
SER A 387
ALA A 377
ASP A 368
 None
 1.11A 3sueC-1kfwA:
undetectable		 3sueC-1kfwA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 195
ILE A  58
GLY A 204
ALA A 146
ALA A 145
 None
 0.97A 3sufD-1kfwA:
undetectable		 3sufD-1kfwA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 4 ASN A 259
PHE A 260
SER A 262
GLN A 320
 None
 1.40A 3v5vA-1kfwA:
0.3		 3v5vA-1kfwA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.25A 3w9tA-1kfwA:
undetectable		 3w9tA-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.24A 3w9tB-1kfwA:
0.0		 3w9tB-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.25A 3w9tC-1kfwA:
0.0		 3w9tC-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.24A 3w9tD-1kfwA:
0.0		 3w9tD-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.24A 3w9tE-1kfwA:
undetectable		 3w9tE-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.25A 3w9tF-1kfwA:
undetectable		 3w9tF-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 VAL A 423
GLY A 420
TYR A 359
ASP A 360
 None
 1.25A 3w9tG-1kfwA:
undetectable		 3w9tG-1kfwA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 11 PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.78A 3wqvA-1kfwA:
44.7		 3wqvA-1kfwA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 11 PHE A  55
GLY A 135
TRP A 136
GLU A 192
TYR A 271
ASP A 272
TYR A 328
ARG A 330
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
None
 0.49A 3wqvA-1kfwA:
44.7		 3wqvA-1kfwA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		7 / 11 PHE A  55
GLY A 135
ASP A 190
TYR A 271
ASP A 272
TYR A 328
TRP A 412
 None
None
None
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.80A 3wqwA-1kfwA:
44.8		 3wqwA-1kfwA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		9 / 11 PHE A  55
GLY A 135
TRP A 136
GLU A 192
TYR A 271
ASP A 272
TYR A 328
ARG A 330
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
None
 0.52A 3wqwA-1kfwA:
44.8		 3wqwA-1kfwA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 11 LEU A 133
ILE A 131
TYR A  53
PHE A  24
TYR A  30
 None
None
None
None
GOL  A 533 (-3.6A)
 1.34A 4a7aA-1kfwA:
undetectable		 4a7aA-1kfwA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.89A 4hajA-1kfwA:
undetectable		 4hajA-1kfwA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.86A 4hb6A-1kfwA:
undetectable		 4hb6A-1kfwA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 8 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.76A 4hb8A-1kfwA:
undetectable		 4hb8A-1kfwA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.89A 4hbfA-1kfwA:
0.0		 4hbfA-1kfwA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.85A 4hc3A-1kfwA:
undetectable		 4hc3A-1kfwA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 409
GLY A 322
THR A  44
GLY A  22
LEU A 414
 None
 1.23A 4n48B-1kfwA:
undetectable		 4n48B-1kfwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 ALA A 307
GLY A 270
GLN A 269
ALA A 240
GLY A 266
 None
None
GOL  A 530 (-3.8A)
None
None
 1.18A 4r29A-1kfwA:
0.0		 4r29A-1kfwA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 4 PHE A  55
ASP A 188
GLY A 135
SER A 132
 None
 1.37A 4xp9C-1kfwA:
undetectable		 4xp9C-1kfwA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 11 VAL A  21
ASN A  20
PHE A 430
GLY A 408
LEU A 325
 None
 1.29A 4zbqA-1kfwA:
undetectable		 4zbqA-1kfwA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 407
GLY A 408
GLY A 409
LEU A 323
LEU A 312
 None
 0.96A 5c0oF-1kfwA:
undetectable		 5c0oF-1kfwA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		6 / 12 PRO A 109
GLY A 173
GLY A 175
GLY A 176
LEU A 168
GLU A 172
 None
 1.45A 5c0oF-1kfwA:
undetectable		 5c0oF-1kfwA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 7 PHE A 214
SER A 143
ALA A 146
PRO A 194
 None
 1.01A 5dzkD-1kfwA:
2.1
5dzkR-1kfwA:
undetectable		 5dzkD-1kfwA:
18.47
5dzkR-1kfwA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 TRP A 136
GLU A 192
ASP A 272
 None
GOL  A 530 (-3.9A)
GOL  A 530 (-3.7A)
 0.31A 5gqbA-1kfwA:
41.3		 5gqbA-1kfwA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		8 / 8 PHE A  55
GLY A 135
TRP A 136
GLU A 192
TYR A 271
ASP A 272
ARG A 330
TRP A 412
 None
None
None
GOL  A 530 (-3.9A)
GOL  A 530 (-4.8A)
GOL  A 530 (-3.7A)
None
None
 0.32A 5gqbA-1kfwA:
41.3		 5gqbA-1kfwA:
26.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 199
GLY A 252
GLY A 195
TRP A 193
ASP A 248
 None
None
None
GOL  A 530 (-4.2A)
None
 1.02A 5njvD-1kfwA:
0.0		 5njvD-1kfwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 7 GLY A 324
LEU A 325
ILE A 401
GLY A 408
LEU A 406
 None
 1.38A 5vkqA-1kfwA:
undetectable
5vkqB-1kfwA:
1.0		 5vkqA-1kfwA:
13.85
5vkqB-1kfwA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 5 MET A  67
TYR A 163
GLY A 166
GLY A 178
 GOL  A 531 (-3.4A)
None
None
None
 1.11A 5x7pA-1kfwA:
1.5		 5x7pA-1kfwA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 ILE A 268
TYR A  23
LEU A 321
ALA A 240
LEU A 263
 None
 1.36A 5zwrB-1kfwA:
0.0		 5zwrB-1kfwA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		5 / 12 GLY A 195
ILE A  58
GLY A 204
ALA A 146
ALA A 145
 None
 0.87A 6c2mD-1kfwA:
undetectable		 6c2mD-1kfwA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 LEU A 288
GLN A 396
LYS A 309
 None
 0.69A 6exiB-1kfwA:
undetectable		 6exiB-1kfwA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 LEU A 288
GLN A 396
LYS A 309
 None
 0.67A 6exiA-1kfwA:
undetectable		 6exiA-1kfwA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		3 / 3 ARG A 174
PHE A 171
GLY A 173
 None
 0.78A 6fgdA-1kfwA:
undetectable		 6fgdA-1kfwA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 1kfw CHITINASE B
(Arthrobacter
sp.
TAD20) 		4 / 4 LEU A 281
ASP A 294
PRO A 295
ARG A 296
 None
 1.02A 6fgdA-1kfwA:
undetectable		 6fgdA-1kfwA:
23.13