SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kg0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 1kg0 GP42 PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 TYR C 117
TYR C 142
PHE C 129
LEU C 177
 None
 1.18A 2w98A-1kg0C:
undetectable
2w98B-1kg0C:
undetectable		 2w98A-1kg0C:
17.18
2w98B-1kg0C:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 1kg0 GP42 PROTEIN
(Human
gammaherpesvirus
4) 		5 / 12 LEU C 149
GLY C 143
VAL C 195
PRO C 202
GLY C 172
 None
 1.25A 5f9zA-1kg0C:
undetectable		 5f9zA-1kg0C:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 1kg0 GP42 PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 GLN C 219
THR C 100
THR C 104
GLY C 113
 None
 0.93A 6gbnC-1kg0C:
undetectable		 6gbnC-1kg0C:
16.44