SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kgp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.76A 11gsA-1kgpA:
undetectable		 11gsA-1kgpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.76A 11gsB-1kgpA:
undetectable		 11gsB-1kgpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A 210
ALA A 271
SER A 164
LEU A 171
TYR A 101
 None
 1.39A 1kiaD-1kgpA:
undetectable		 1kiaD-1kgpA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
GLU A 202
 MN  A1001 (-2.7A)
MN  A1001 ( 2.3A)
MN  A1001 (-3.2A)
None
MN  A1002 (-1.8A)
None
None
None
MN  A1001 ( 2.2A)
 0.84A 1rnrA-1kgpA:
30.9		 1rnrA-1kgpA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 11 LEU A 167
GLU A 168
TYR A 173
SER A 174
PHE A 176
 None
MN  A1002 (-1.8A)
None
None
None
 1.32A 1rnrA-1kgpA:
30.9		 1rnrA-1kgpA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 12 ASP A  77
GLU A 108
HIS A 111
LEU A 167
GLU A 168
TYR A 173
PHE A 176
ILE A 198
GLU A 202
 MN  A1001 (-2.7A)
MN  A1001 ( 2.3A)
MN  A1001 (-3.2A)
None
MN  A1002 (-1.8A)
None
None
None
MN  A1001 ( 2.2A)
 0.76A 1rnrB-1kgpA:
31.3		 1rnrB-1kgpA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 12 ASP A  77
GLU A 108
HIS A 111
TYR A 115
LEU A 167
GLU A 168
TYR A 173
ILE A 198
GLU A 202
 MN  A1001 (-2.7A)
MN  A1001 ( 2.3A)
MN  A1001 (-3.2A)
None
None
MN  A1002 (-1.8A)
None
None
MN  A1001 ( 2.2A)
 0.86A 1rnrB-1kgpA:
31.3		 1rnrB-1kgpA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 LEU A 166
TYR A 213
GLY A 206
LEU A 272
 None
 0.95A 1s1xA-1kgpA:
undetectable		 1s1xA-1kgpA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XMU_A_ROFA101_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  51
LEU A 188
PRO A 179
ILE A 194
PHE A  70
 None
 1.49A 1xmuA-1kgpA:
undetectable		 1xmuA-1kgpA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  51
LEU A 188
PRO A 179
ILE A 194
PHE A  70
 None
 1.45A 1xoqA-1kgpA:
undetectable		 1xoqA-1kgpA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  51
LEU A 188
PRO A 179
ILE A 194
PHE A  70
 None
 1.48A 1xoqB-1kgpA:
undetectable		 1xoqB-1kgpA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.75A 2gssA-1kgpA:
undetectable		 2gssA-1kgpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.75A 2gssB-1kgpA:
undetectable		 2gssB-1kgpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.79A 3hjoA-1kgpA:
undetectable		 3hjoA-1kgpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_2
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 6 THR A  71
ASN A 138
TRP A 134
TRP A 256
 None
 1.35A 3jzjA-1kgpA:
0.0		 3jzjA-1kgpA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.73A 3n9jA-1kgpA:
undetectable		 3n9jA-1kgpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 8 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.73A 3n9jB-1kgpA:
undetectable		 3n9jB-1kgpA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 10 ILE A 199
ALA A 192
PHE A 176
SER A 114
ILE A 198
 None
 1.23A 3qgtA-1kgpA:
undetectable		 3qgtA-1kgpA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 5 PHE A 176
TYR A 173
PHE A 263
ILE A 195
 None
 1.14A 4jx1E-1kgpA:
0.1		 4jx1E-1kgpA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  81
GLN A  80
ALA A 105
LEU A  89
SER A 164
 None
 1.21A 4pb1A-1kgpA:
1.8		 4pb1A-1kgpA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  81
GLN A  80
ALA A 105
LEU A  89
SER A 164
 None
 1.20A 4pd9A-1kgpA:
0.3		 4pd9A-1kgpA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 8 LYS A 270
ALA A 271
GLY A 276
LEU A 275
LEU A 166
 None
 1.46A 4po0A-1kgpA:
undetectable		 4po0A-1kgpA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 ASP A  77
TYR A 115
THR A 191
ALA A 192
TRP A  41
 MN  A1001 (-2.7A)
None
None
None
None
 1.36A 4u15A-1kgpA:
1.9		 4u15A-1kgpA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		4 / 7 LEU A  73
PHE A  70
THR A 191
THR A 247
 None
 0.97A 5vc0A-1kgpA:
0.1		 5vc0A-1kgpA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		7 / 9 LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.52A 6ebpA-1kgpA:
42.4		 6ebpA-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		6 / 9 LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
MN  A1001 (-2.7A)
None
None
None
 0.69A 6ebpA-1kgpA:
42.4		 6ebpA-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.49A 6ebpB-1kgpA:
42.1		 6ebpB-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		7 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
 0.63A 6ebpB-1kgpA:
42.1		 6ebpB-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		6 / 10 LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 198
 None
None
MN  A1001 (-2.7A)
None
None
None
 0.67A 6ebpC-1kgpA:
42.3		 6ebpC-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.45A 6ebpC-1kgpA:
42.3		 6ebpC-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.43A 6ebpD-1kgpA:
42.2		 6ebpD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 10 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.62A 6ebpD-1kgpA:
42.2		 6ebpD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
 0.46A 6ebzA-1kgpA:
42.2		 6ebzA-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.58A 6ebzA-1kgpA:
42.2		 6ebzA-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
 0.44A 6ebzB-1kgpA:
42.5		 6ebzB-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.59A 6ebzB-1kgpA:
42.5		 6ebzB-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		10 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
None
 0.44A 6ebzC-1kgpA:
42.5		 6ebzC-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
 0.49A 6ebzD-1kgpA:
42.2		 6ebzD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.58A 6ebzD-1kgpA:
42.2		 6ebzD-1kgpA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.63A 6gp2A-1kgpA:
41.5		 6gp2A-1kgpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.62A 6gp2A-1kgpA:
41.5		 6gp2A-1kgpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_A_DAHA126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
 0.63A 6gp2A-1kgpA:
41.5		 6gp2A-1kgpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		9 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
ILE A 118
PHE A 119
PHE A 176
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
None
 0.75A 6gp2B-1kgpA:
41.1		 6gp2B-1kgpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GP2_B_DAHB126_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA CHAIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		8 / 11 PHE A  70
LEU A  73
THR A  74
ASP A  77
SER A 114
ILE A 118
ILE A 195
ILE A 198
 None
None
None
MN  A1001 (-2.7A)
None
None
None
None
 0.66A 6gp2B-1kgpA:
41.1		 6gp2B-1kgpA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F
(Corynebacterium
ammoniagenes) 		5 / 12 VAL A  69
THR A 247
ILE A 250
PHE A 263
MET A 180
 None
 1.12A 6j20A-1kgpA:
1.2		 6j20A-1kgpA:
18.96