SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 10 ALA A  30
LEU A  99
LEU A  59
ALA A  33
ILE A  57
 None
None
None
ATP  A 510 (-3.9A)
None
 1.19A 1g5yC-1kh2A:
undetectable		 1g5yC-1kh2A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 1k2rA-1kh2A:
0.0
1k2rB-1kh2A:
0.0		 1k2rA-1kh2A:
22.91
1k2rB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1k2rA-1kh2A:
0.0
1k2rB-1kh2A:
0.0		 1k2rA-1kh2A:
22.91
1k2rB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.27A 1k2sA-1kh2A:
0.0
1k2sB-1kh2A:
0.0		 1k2sA-1kh2A:
22.91
1k2sB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 1k2sA-1kh2A:
0.0
1k2sB-1kh2A:
0.0		 1k2sA-1kh2A:
22.91
1k2sB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1k2tA-1kh2A:
0.1
1k2tB-1kh2A:
0.0		 1k2tA-1kh2A:
22.91
1k2tB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1k2tA-1kh2A:
0.1
1k2tB-1kh2A:
0.0		 1k2tA-1kh2A:
22.91
1k2tB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 1k2uA-1kh2A:
0.0
1k2uB-1kh2A:
0.0		 1k2uA-1kh2A:
22.91
1k2uB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 1k2uA-1kh2A:
0.0
1k2uB-1kh2A:
0.0		 1k2uA-1kh2A:
22.91
1k2uB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1lzxA-1kh2A:
0.0
1lzxB-1kh2A:
0.0		 1lzxA-1kh2A:
22.91
1lzxB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 1lzxA-1kh2A:
0.0
1lzxB-1kh2A:
0.0		 1lzxA-1kh2A:
22.91
1lzxB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 1lzzA-1kh2A:
0.6
1lzzB-1kh2A:
0.0		 1lzzA-1kh2A:
22.91
1lzzB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 1lzzA-1kh2A:
0.6
1lzzB-1kh2A:
0.0		 1lzzA-1kh2A:
22.91
1lzzB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 1m00A-1kh2A:
0.1
1m00B-1kh2A:
0.0		 1m00A-1kh2A:
22.91
1m00B-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 1m00A-1kh2A:
0.1
1m00B-1kh2A:
0.0		 1m00A-1kh2A:
22.91
1m00B-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 1mmvA-1kh2A:
0.0
1mmvB-1kh2A:
0.0		 1mmvA-1kh2A:
22.91
1mmvB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 1mmvA-1kh2A:
0.0
1mmvB-1kh2A:
0.0		 1mmvA-1kh2A:
22.91
1mmvB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1mmwA-1kh2A:
0.0
1mmwB-1kh2A:
0.0		 1mmwA-1kh2A:
22.91
1mmwB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1mmwA-1kh2A:
0.0
1mmwB-1kh2A:
0.0		 1mmwA-1kh2A:
22.91
1mmwB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ILE A  57
ALA A  58
THR A  51
LEU A  49
LEU A  17
 None
 1.20A 1og5B-1kh2A:
0.0		 1og5B-1kh2A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 1om4A-1kh2A:
0.0
1om4B-1kh2A:
0.0		 1om4A-1kh2A:
22.65
1om4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 1om4A-1kh2A:
0.0
1om4B-1kh2A:
0.0		 1om4A-1kh2A:
22.65
1om4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 1om5A-1kh2A:
0.1
1om5B-1kh2A:
0.0		 1om5A-1kh2A:
22.65
1om5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1om5A-1kh2A:
0.1
1om5B-1kh2A:
0.0		 1om5A-1kh2A:
22.65
1om5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1p6hA-1kh2A:
0.0
1p6hB-1kh2A:
0.0		 1p6hA-1kh2A:
22.65
1p6hB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 1p6hA-1kh2A:
0.0
1p6hB-1kh2A:
0.0		 1p6hA-1kh2A:
22.65
1p6hB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 1p6iA-1kh2A:
0.5
1p6iB-1kh2A:
0.0		 1p6iA-1kh2A:
22.65
1p6iB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 1p6iA-1kh2A:
0.5
1p6iB-1kh2A:
0.0		 1p6iA-1kh2A:
22.65
1p6iB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1p6jA-1kh2A:
0.0
1p6jB-1kh2A:
0.0		 1p6jA-1kh2A:
22.65
1p6jB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 1p6jA-1kh2A:
0.0
1p6jB-1kh2A:
0.0		 1p6jA-1kh2A:
22.65
1p6jB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 1p6kA-1kh2A:
0.6
1p6kB-1kh2A:
0.0		 1p6kA-1kh2A:
22.65
1p6kB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1p6kA-1kh2A:
0.6
1p6kB-1kh2A:
0.0		 1p6kA-1kh2A:
22.65
1p6kB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 1rs6A-1kh2A:
0.0
1rs6B-1kh2A:
0.0		 1rs6A-1kh2A:
22.65
1rs6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 1rs6A-1kh2A:
undetectable
1rs6B-1kh2A:
0.0		 1rs6A-1kh2A:
22.65
1rs6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 1rs7A-1kh2A:
0.0
1rs7B-1kh2A:
0.0		 1rs7A-1kh2A:
22.65
1rs7B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1rs7A-1kh2A:
0.0
1rs7B-1kh2A:
0.0		 1rs7A-1kh2A:
22.65
1rs7B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUF_A_AZ1A502_1
(DIAMINOPIMELATE
DECARBOXYLASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 9 GLY A 119
ARG A 124
TYR A 270
GLU A 258
SER A 266
 None
 1.41A 1tufA-1kh2A:
0.1
1tufB-1kh2A:
2.0		 1tufA-1kh2A:
22.34
1tufB-1kh2A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 1zvlA-1kh2A:
0.0
1zvlB-1kh2A:
0.0		 1zvlA-1kh2A:
22.65
1zvlB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.38A 1zvlA-1kh2A:
0.0
1zvlB-1kh2A:
0.0		 1zvlA-1kh2A:
22.65
1zvlB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 1zzqA-1kh2A:
0.0
1zzqB-1kh2A:
0.0		 1zzqA-1kh2A:
22.91
1zzqB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 1zzqA-1kh2A:
0.0
1zzqB-1kh2A:
0.0		 1zzqA-1kh2A:
22.91
1zzqB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 2g6hA-1kh2A:
undetectable
2g6hB-1kh2A:
0.0		 2g6hA-1kh2A:
22.91
2g6hB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 2g6hA-1kh2A:
undetectable
2g6hB-1kh2A:
0.0		 2g6hA-1kh2A:
22.91
2g6hB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 2g6kA-1kh2A:
0.0
2g6kB-1kh2A:
0.0		 2g6kA-1kh2A:
22.91
2g6kB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 2g6kA-1kh2A:
0.0
2g6kB-1kh2A:
0.0		 2g6kA-1kh2A:
22.91
2g6kB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 2g6mA-1kh2A:
0.0
2g6mB-1kh2A:
0.0		 2g6mA-1kh2A:
22.91
2g6mB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 2g6mA-1kh2A:
0.0
2g6mB-1kh2A:
0.0		 2g6mA-1kh2A:
22.91
2g6mB-1kh2A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 2hx3A-1kh2A:
0.0
2hx3B-1kh2A:
0.0		 2hx3A-1kh2A:
22.65
2hx3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 2hx3A-1kh2A:
0.0
2hx3B-1kh2A:
0.0		 2hx3A-1kh2A:
22.65
2hx3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 2hx4A-1kh2A:
0.0
2hx4B-1kh2A:
0.0		 2hx4A-1kh2A:
22.65
2hx4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 2hx4A-1kh2A:
undetectable
2hx4B-1kh2A:
0.0		 2hx4A-1kh2A:
22.65
2hx4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 SER A  89
LEU A  86
ASP A 121
GLU A 258
 None
 0.96A 2j2pE-1kh2A:
undetectable
2j2pF-1kh2A:
undetectable		 2j2pE-1kh2A:
18.09
2j2pF-1kh2A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3b3mA-1kh2A:
0.5
3b3mB-1kh2A:
0.0		 3b3mA-1kh2A:
22.65
3b3mB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3b3mA-1kh2A:
0.5
3b3mB-1kh2A:
0.0		 3b3mA-1kh2A:
22.65
3b3mB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 3b3nA-1kh2A:
0.0
3b3nB-1kh2A:
0.0		 3b3nA-1kh2A:
22.65
3b3nB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3b3nA-1kh2A:
0.0
3b3nB-1kh2A:
0.0		 3b3nA-1kh2A:
22.65
3b3nB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3b3oA-1kh2A:
0.0
3b3oB-1kh2A:
0.0		 3b3oA-1kh2A:
22.65
3b3oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3b3oA-1kh2A:
0.0
3b3oB-1kh2A:
0.0		 3b3oA-1kh2A:
22.65
3b3oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.22A 3b3pA-1kh2A:
0.0
3b3pB-1kh2A:
0.1		 3b3pA-1kh2A:
22.65
3b3pB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 3b3pA-1kh2A:
0.0
3b3pB-1kh2A:
0.1		 3b3pA-1kh2A:
22.65
3b3pB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.26A 3dqrA-1kh2A:
0.0
3dqrB-1kh2A:
0.0		 3dqrA-1kh2A:
22.65
3dqrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3dqrA-1kh2A:
undetectable
3dqrB-1kh2A:
undetectable		 3dqrA-1kh2A:
22.65
3dqrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 8 GLY A 223
ALA A 330
ASP A 327
GLY A  77
VAL A 294
 None
 1.28A 3em6A-1kh2A:
undetectable		 3em6A-1kh2A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3fc5A-1kh2A:
0.1
3fc5B-1kh2A:
0.0		 3fc5A-1kh2A:
22.27
3fc5B-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3fc5A-1kh2A:
0.1
3fc5B-1kh2A:
0.0		 3fc5A-1kh2A:
22.27
3fc5B-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 TYR A 279
VAL A  79
VAL A 254
GLY A  82
 None
 0.89A 3hjoA-1kh2A:
undetectable		 3hjoA-1kh2A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3hsnA-1kh2A:
0.0
3hsnB-1kh2A:
0.0		 3hsnA-1kh2A:
22.65
3hsnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3hsnA-1kh2A:
0.0
3hsnB-1kh2A:
0.0		 3hsnA-1kh2A:
22.65
3hsnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3hsoA-1kh2A:
0.0
3hsoB-1kh2A:
0.0		 3hsoA-1kh2A:
22.65
3hsoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3hsoA-1kh2A:
0.0
3hsoB-1kh2A:
0.0		 3hsoA-1kh2A:
22.65
3hsoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3hspA-1kh2A:
0.0
3hspB-1kh2A:
0.0		 3hspA-1kh2A:
22.65
3hspB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3hspA-1kh2A:
0.0
3hspB-1kh2A:
0.0		 3hspA-1kh2A:
22.65
3hspB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 3jt3A-1kh2A:
0.0
3jt3B-1kh2A:
0.1		 3jt3A-1kh2A:
22.65
3jt3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3jt3A-1kh2A:
0.0
3jt3B-1kh2A:
0.1		 3jt3A-1kh2A:
22.65
3jt3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jt4A-1kh2A:
0.5
3jt4B-1kh2A:
0.1		 3jt4A-1kh2A:
22.65
3jt4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3jt4A-1kh2A:
0.5
3jt4B-1kh2A:
0.1		 3jt4A-1kh2A:
22.65
3jt4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3jt5A-1kh2A:
0.0
3jt5B-1kh2A:
0.0		 3jt5A-1kh2A:
22.65
3jt5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 3jt5A-1kh2A:
0.0
3jt5B-1kh2A:
0.0		 3jt5A-1kh2A:
22.65
3jt5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jt6A-1kh2A:
0.0
3jt6B-1kh2A:
0.6		 3jt6A-1kh2A:
22.65
3jt6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3jt6A-1kh2A:
0.0
3jt6B-1kh2A:
0.6		 3jt6A-1kh2A:
22.65
3jt6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3jt7A-1kh2A:
0.0
3jt7B-1kh2A:
0.0		 3jt7A-1kh2A:
22.65
3jt7B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3jt7A-1kh2A:
0.0
3jt7B-1kh2A:
0.0		 3jt7A-1kh2A:
22.65
3jt7B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jt8A-1kh2A:
0.0
3jt8B-1kh2A:
0.5		 3jt8A-1kh2A:
22.65
3jt8B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3jt8A-1kh2A:
0.0
3jt8B-1kh2A:
0.5		 3jt8A-1kh2A:
22.65
3jt8B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 3jt9A-1kh2A:
0.0
3jt9B-1kh2A:
0.1		 3jt9A-1kh2A:
22.65
3jt9B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3jt9A-1kh2A:
0.0
3jt9B-1kh2A:
0.1		 3jt9A-1kh2A:
22.65
3jt9B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jtaA-1kh2A:
0.0
3jtaB-1kh2A:
0.6		 3jtaA-1kh2A:
22.65
3jtaB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.37A 3jtaA-1kh2A:
0.0
3jtaB-1kh2A:
0.6		 3jtaA-1kh2A:
22.65
3jtaB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3jwsA-1kh2A:
0.2
3jwsB-1kh2A:
0.0		 3jwsA-1kh2A:
22.81
3jwsB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3jwsA-1kh2A:
0.2
3jwsB-1kh2A:
0.0		 3jwsA-1kh2A:
22.81
3jwsB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jwtA-1kh2A:
0.0
3jwtB-1kh2A:
0.0		 3jwtA-1kh2A:
22.81
3jwtB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3jwtA-1kh2A:
undetectable
3jwtB-1kh2A:
0.0		 3jwtA-1kh2A:
22.81
3jwtB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 3jwuA-1kh2A:
0.0
3jwuB-1kh2A:
0.1		 3jwuA-1kh2A:
22.81
3jwuB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3jwuA-1kh2A:
0.0
3jwuB-1kh2A:
0.1		 3jwuA-1kh2A:
22.81
3jwuB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 3jwvA-1kh2A:
0.0
3jwvB-1kh2A:
0.1		 3jwvA-1kh2A:
22.81
3jwvB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3jwvA-1kh2A:
0.0
3jwvB-1kh2A:
0.1		 3jwvA-1kh2A:
22.81
3jwvB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3jx0A-1kh2A:
0.3
3jx0B-1kh2A:
0.0		 3jx0A-1kh2A:
22.65
3jx0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3jx0A-1kh2A:
0.3
3jx0B-1kh2A:
0.0		 3jx0A-1kh2A:
22.65
3jx0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3jx1A-1kh2A:
0.5
3jx1B-1kh2A:
0.0		 3jx1A-1kh2A:
22.65
3jx1B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3jx1A-1kh2A:
undetectable
3jx1B-1kh2A:
0.0		 3jx1A-1kh2A:
22.65
3jx1B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3jx5A-1kh2A:
undetectable
3jx5B-1kh2A:
0.5		 3jx5A-1kh2A:
22.65
3jx5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 TYR A 279
VAL A  79
VAL A 254
GLY A  82
 None
 0.89A 3kmoB-1kh2A:
undetectable		 3kmoB-1kh2A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 8 LEU A 278
VAL A 228
ILE A 245
VAL A 216
LEU A 339
 None
 1.39A 3kp6A-1kh2A:
undetectable
3kp6B-1kh2A:
undetectable		 3kp6A-1kh2A:
17.75
3kp6B-1kh2A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3n2rA-1kh2A:
0.0
3n2rB-1kh2A:
0.0		 3n2rA-1kh2A:
22.65
3n2rB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3n2rA-1kh2A:
0.0
3n2rB-1kh2A:
0.0		 3n2rA-1kh2A:
22.65
3n2rB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.41A 3n5vA-1kh2A:
0.0
3n5vB-1kh2A:
0.1		 3n5vA-1kh2A:
22.65
3n5vB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.39A 3n5vA-1kh2A:
0.0
3n5vB-1kh2A:
0.1		 3n5vA-1kh2A:
22.65
3n5vB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.37A 3n5yA-1kh2A:
0.0
3n5yB-1kh2A:
0.0		 3n5yA-1kh2A:
22.65
3n5yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3n5yA-1kh2A:
0.0
3n5yB-1kh2A:
0.0		 3n5yA-1kh2A:
22.65
3n5yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 3n5zA-1kh2A:
0.0
3n5zB-1kh2A:
0.3		 3n5zA-1kh2A:
22.65
3n5zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3n5zA-1kh2A:
0.0
3n5zB-1kh2A:
0.3		 3n5zA-1kh2A:
22.65
3n5zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3nlkA-1kh2A:
0.0
3nlkB-1kh2A:
0.1		 3nlkA-1kh2A:
22.81
3nlkB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nlkA-1kh2A:
0.0
3nlkB-1kh2A:
0.1		 3nlkA-1kh2A:
22.81
3nlkB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3nlmA-1kh2A:
0.0
3nlmB-1kh2A:
0.1		 3nlmA-1kh2A:
22.65
3nlmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3nlmA-1kh2A:
0.0
3nlmB-1kh2A:
0.1		 3nlmA-1kh2A:
22.65
3nlmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3nlnA-1kh2A:
0.0
3nlnB-1kh2A:
0.1		 3nlnA-1kh2A:
22.81
3nlnB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nlnA-1kh2A:
0.0
3nlnB-1kh2A:
0.1		 3nlnA-1kh2A:
22.81
3nlnB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3nloA-1kh2A:
0.0
3nloB-1kh2A:
0.1		 3nloA-1kh2A:
22.81
3nloB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.37A 3nloA-1kh2A:
0.0
3nloB-1kh2A:
0.1		 3nloA-1kh2A:
22.81
3nloB-1kh2A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 3nlqA-1kh2A:
0.0
3nlqB-1kh2A:
0.0		 3nlqA-1kh2A:
22.65
3nlqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3nlvA-1kh2A:
0.5
3nlvB-1kh2A:
0.1		 3nlvA-1kh2A:
22.65
3nlvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3nlvA-1kh2A:
0.5
3nlvB-1kh2A:
0.1		 3nlvA-1kh2A:
22.65
3nlvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3nlwA-1kh2A:
0.0
3nlwB-1kh2A:
0.1		 3nlwA-1kh2A:
22.65
3nlwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3nlwA-1kh2A:
0.0
3nlwB-1kh2A:
0.1		 3nlwA-1kh2A:
22.65
3nlwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3nlxA-1kh2A:
0.0
3nlxB-1kh2A:
0.0		 3nlxA-1kh2A:
22.65
3nlxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nlxA-1kh2A:
0.0
3nlxB-1kh2A:
0.0		 3nlxA-1kh2A:
22.65
3nlxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 3nlyA-1kh2A:
0.0
3nlyB-1kh2A:
0.1		 3nlyA-1kh2A:
22.65
3nlyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3nlyA-1kh2A:
undetectable
3nlyB-1kh2A:
0.1		 3nlyA-1kh2A:
22.65
3nlyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3nlzA-1kh2A:
0.0
3nlzB-1kh2A:
0.0		 3nlzA-1kh2A:
22.65
3nlzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3nlzA-1kh2A:
0.0
3nlzB-1kh2A:
0.0		 3nlzA-1kh2A:
22.65
3nlzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3nm0A-1kh2A:
0.3
3nm0B-1kh2A:
0.0		 3nm0A-1kh2A:
22.65
3nm0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nm0A-1kh2A:
0.3
3nm0B-1kh2A:
0.0		 3nm0A-1kh2A:
22.65
3nm0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3nnyA-1kh2A:
0.1
3nnyB-1kh2A:
0.6		 3nnyA-1kh2A:
22.65
3nnyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nnyA-1kh2A:
0.1
3nnyB-1kh2A:
0.6		 3nnyA-1kh2A:
22.65
3nnyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3nnzA-1kh2A:
0.0
3nnzB-1kh2A:
0.0		 3nnzA-1kh2A:
22.65
3nnzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3nnzA-1kh2A:
0.0
3nnzB-1kh2A:
0.0		 3nnzA-1kh2A:
22.65
3nnzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 ASP A 121
GLU A 258
SER A   8
 None
None
ATP  A 510 (-2.2A)
 0.82A 3p2kA-1kh2A:
undetectable		 3p2kA-1kh2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3pneA-1kh2A:
0.0
3pneB-1kh2A:
0.1		 3pneA-1kh2A:
22.65
3pneB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3pneA-1kh2A:
0.0
3pneB-1kh2A:
0.1		 3pneA-1kh2A:
22.65
3pneB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 3pnfA-1kh2A:
0.0
3pnfB-1kh2A:
0.0		 3pnfA-1kh2A:
22.65
3pnfB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3pnfA-1kh2A:
0.0
3pnfB-1kh2A:
0.0		 3pnfA-1kh2A:
22.65
3pnfB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 3pngA-1kh2A:
0.0
3pngB-1kh2A:
0.0		 3pngA-1kh2A:
22.65
3pngB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3pngA-1kh2A:
0.0
3pngB-1kh2A:
0.0		 3pngA-1kh2A:
22.65
3pngB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3q99A-1kh2A:
0.0
3q99B-1kh2A:
0.1		 3q99A-1kh2A:
22.65
3q99B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3q99A-1kh2A:
0.0
3q99B-1kh2A:
0.1		 3q99A-1kh2A:
22.65
3q99B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 3q9aA-1kh2A:
0.0
3q9aB-1kh2A:
0.0		 3q9aA-1kh2A:
22.65
3q9aB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3q9aA-1kh2A:
0.0
3q9aB-1kh2A:
0.0		 3q9aA-1kh2A:
22.65
3q9aB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3rqjA-1kh2A:
0.0
3rqjB-1kh2A:
0.0		 3rqjA-1kh2A:
22.65
3rqjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 3rqjA-1kh2A:
0.0
3rqjB-1kh2A:
0.0		 3rqjA-1kh2A:
22.65
3rqjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3rqkA-1kh2A:
0.5
3rqkB-1kh2A:
0.5		 3rqkA-1kh2A:
22.65
3rqkB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3rqkA-1kh2A:
0.5
3rqkB-1kh2A:
0.5		 3rqkA-1kh2A:
22.65
3rqkB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 3rqlA-1kh2A:
0.0
3rqlB-1kh2A:
0.0		 3rqlA-1kh2A:
22.65
3rqlB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 3rqlA-1kh2A:
0.0
3rqlB-1kh2A:
0.0		 3rqlA-1kh2A:
22.65
3rqlB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3rqmA-1kh2A:
0.0
3rqmB-1kh2A:
0.0		 3rqmA-1kh2A:
22.65
3rqmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3rqmA-1kh2A:
0.0
3rqmB-1kh2A:
0.0		 3rqmA-1kh2A:
22.65
3rqmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3rqnA-1kh2A:
0.0
3rqnB-1kh2A:
0.0		 3rqnA-1kh2A:
22.65
3rqnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3rqnA-1kh2A:
0.0
3rqnB-1kh2A:
0.0		 3rqnA-1kh2A:
22.65
3rqnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A 114
ALA A   6
PHE A  31
THR A  32
ALA A  33
 ATP  A 510 (-3.1A)
ATP  A 510 (-3.0A)
None
ATP  A 510 ( 4.7A)
ATP  A 510 (-3.9A)
 1.10A 3sugA-1kh2A:
undetectable		 3sugA-1kh2A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3svpA-1kh2A:
0.0
3svpB-1kh2A:
0.1		 3svpA-1kh2A:
22.65
3svpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 3svpA-1kh2A:
0.0
3svpB-1kh2A:
0.1		 3svpA-1kh2A:
22.65
3svpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 3svqA-1kh2A:
0.1
3svqB-1kh2A:
0.0		 3svqA-1kh2A:
22.65
3svqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3svqA-1kh2A:
0.1
3svqB-1kh2A:
0.0		 3svqA-1kh2A:
22.65
3svqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3tylA-1kh2A:
0.0
3tylB-1kh2A:
0.0		 3tylA-1kh2A:
22.65
3tylB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3tylA-1kh2A:
0.0
3tylB-1kh2A:
0.0		 3tylA-1kh2A:
22.65
3tylB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3tymA-1kh2A:
0.4
3tymB-1kh2A:
undetectable		 3tymA-1kh2A:
22.65
3tymB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3tymA-1kh2A:
0.0
3tymB-1kh2A:
0.0		 3tymA-1kh2A:
22.65
3tymB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3tynA-1kh2A:
0.0
3tynB-1kh2A:
0.1		 3tynA-1kh2A:
22.65
3tynB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3tynA-1kh2A:
0.0
3tynB-1kh2A:
0.1		 3tynA-1kh2A:
22.65
3tynB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3tyoA-1kh2A:
0.6
3tyoB-1kh2A:
0.1		 3tyoA-1kh2A:
22.65
3tyoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3tyoA-1kh2A:
0.6
3tyoB-1kh2A:
0.1		 3tyoA-1kh2A:
22.65
3tyoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.37A 3ufoA-1kh2A:
0.1
3ufoB-1kh2A:
0.1		 3ufoA-1kh2A:
22.65
3ufoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3ufoA-1kh2A:
0.1
3ufoB-1kh2A:
0.1		 3ufoA-1kh2A:
22.65
3ufoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3ufpA-1kh2A:
0.0
3ufpB-1kh2A:
0.1		 3ufpA-1kh2A:
22.65
3ufpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3ufpA-1kh2A:
0.0
3ufpB-1kh2A:
0.1		 3ufpA-1kh2A:
22.65
3ufpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3ufqA-1kh2A:
0.0
3ufqB-1kh2A:
0.5		 3ufqA-1kh2A:
22.65
3ufqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 3ufqA-1kh2A:
0.0
3ufqB-1kh2A:
0.5		 3ufqA-1kh2A:
22.65
3ufqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.13A 3ufrA-1kh2A:
0.0
3ufrB-1kh2A:
0.6		 3ufrA-1kh2A:
22.65
3ufrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3ufrA-1kh2A:
0.0
3ufrB-1kh2A:
0.6		 3ufrA-1kh2A:
22.65
3ufrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 3ufsA-1kh2A:
0.0
3ufsB-1kh2A:
0.0		 3ufsA-1kh2A:
22.65
3ufsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 3ufsA-1kh2A:
0.0
3ufsB-1kh2A:
0.0		 3ufsA-1kh2A:
22.65
3ufsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 3uftA-1kh2A:
0.1
3uftB-1kh2A:
0.0		 3uftA-1kh2A:
22.65
3uftB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 3uftA-1kh2A:
0.1
3uftB-1kh2A:
0.0		 3uftA-1kh2A:
22.65
3uftB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 3ufuA-1kh2A:
0.0
3ufuB-1kh2A:
0.0		 3ufuA-1kh2A:
22.65
3ufuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 3ufuA-1kh2A:
0.0
3ufuB-1kh2A:
0.0		 3ufuA-1kh2A:
22.65
3ufuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3ufvA-1kh2A:
0.1
3ufvB-1kh2A:
0.0		 3ufvA-1kh2A:
22.65
3ufvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 3ufvA-1kh2A:
0.6
3ufvB-1kh2A:
0.0		 3ufvA-1kh2A:
22.65
3ufvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 3ufwA-1kh2A:
0.7
3ufwB-1kh2A:
0.1		 3ufwA-1kh2A:
22.65
3ufwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 3ufwA-1kh2A:
0.7
3ufwB-1kh2A:
0.1		 3ufwA-1kh2A:
22.65
3ufwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A  99
ALA A 112
THR A  51
ALA A  53
ILE A  29
 None
 1.02A 3ut5B-1kh2A:
undetectable		 3ut5B-1kh2A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLU A  81
TYR A 270
MET A  73
ILE A  90
GLU A 184
 None
 1.43A 4a97F-1kh2A:
0.6
4a97J-1kh2A:
0.0		 4a97F-1kh2A:
23.19
4a97J-1kh2A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 MET A  73
ILE A  90
GLU A 184
GLU A  81
TYR A 270
 None
 1.40A 4a97F-1kh2A:
0.6
4a97G-1kh2A:
0.7		 4a97F-1kh2A:
23.19
4a97G-1kh2A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4c39A-1kh2A:
0.5
4c39B-1kh2A:
0.0		 4c39A-1kh2A:
22.65
4c39B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4c39A-1kh2A:
0.5
4c39B-1kh2A:
0.0		 4c39A-1kh2A:
22.65
4c39B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 4camA-1kh2A:
0.2
4camB-1kh2A:
0.5		 4camA-1kh2A:
22.65
4camB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4camA-1kh2A:
0.2
4camB-1kh2A:
0.5		 4camA-1kh2A:
22.65
4camB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4canA-1kh2A:
0.1
4canB-1kh2A:
0.3		 4canA-1kh2A:
22.65
4canB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4canA-1kh2A:
0.1
4canB-1kh2A:
0.3		 4canA-1kh2A:
22.65
4canB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 4caoA-1kh2A:
0.0
4caoB-1kh2A:
0.5		 4caoA-1kh2A:
22.65
4caoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4caoA-1kh2A:
0.0
4caoB-1kh2A:
0.5		 4caoA-1kh2A:
22.65
4caoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4capA-1kh2A:
0.1
4capB-1kh2A:
0.0		 4capA-1kh2A:
22.65
4capB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4capA-1kh2A:
0.1
4capB-1kh2A:
0.0		 4capA-1kh2A:
22.65
4capB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4caqA-1kh2A:
0.0
4caqB-1kh2A:
0.6		 4caqA-1kh2A:
22.65
4caqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4caqA-1kh2A:
0.0
4caqB-1kh2A:
0.6		 4caqA-1kh2A:
22.65
4caqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4cdtA-1kh2A:
0.0
4cdtB-1kh2A:
0.5		 4cdtA-1kh2A:
22.65
4cdtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4cdtA-1kh2A:
0.0
4cdtB-1kh2A:
0.5		 4cdtA-1kh2A:
22.65
4cdtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4ctpA-1kh2A:
0.6
4ctpB-1kh2A:
0.0		 4ctpA-1kh2A:
22.65
4ctpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4ctpA-1kh2A:
0.6
4ctpB-1kh2A:
0.0		 4ctpA-1kh2A:
22.65
4ctpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4ctqA-1kh2A:
0.6
4ctqB-1kh2A:
0.0		 4ctqA-1kh2A:
22.65
4ctqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4ctqA-1kh2A:
0.6
4ctqB-1kh2A:
0.0		 4ctqA-1kh2A:
22.65
4ctqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.39A 4ctrA-1kh2A:
0.1
4ctrB-1kh2A:
0.3		 4ctrA-1kh2A:
22.65
4ctrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4ctrA-1kh2A:
0.1
4ctrB-1kh2A:
0.3		 4ctrA-1kh2A:
22.65
4ctrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 4cttA-1kh2A:
0.0
4cttB-1kh2A:
0.0		 4cttA-1kh2A:
22.65
4cttB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4cttA-1kh2A:
0.0
4cttB-1kh2A:
0.0		 4cttA-1kh2A:
22.65
4cttB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4ctuA-1kh2A:
0.0
4ctuB-1kh2A:
0.6		 4ctuA-1kh2A:
22.65
4ctuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4ctuA-1kh2A:
0.0
4ctuB-1kh2A:
0.6		 4ctuA-1kh2A:
22.65
4ctuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4ctvA-1kh2A:
0.6
4ctvB-1kh2A:
0.1		 4ctvA-1kh2A:
22.65
4ctvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4ctvA-1kh2A:
0.6
4ctvB-1kh2A:
0.1		 4ctvA-1kh2A:
22.65
4ctvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4ctwA-1kh2A:
0.6
4ctwB-1kh2A:
0.0		 4ctwA-1kh2A:
22.65
4ctwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4ctwA-1kh2A:
0.0
4ctwB-1kh2A:
0.0		 4ctwA-1kh2A:
22.65
4ctwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4ctxA-1kh2A:
0.6
4ctxB-1kh2A:
0.0		 4ctxA-1kh2A:
22.65
4ctxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4ctxA-1kh2A:
0.1
4ctxB-1kh2A:
0.0		 4ctxA-1kh2A:
22.65
4ctxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4cx5A-1kh2A:
0.0
4cx5B-1kh2A:
0.0		 4cx5A-1kh2A:
22.65
4cx5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4cx5A-1kh2A:
0.0
4cx5B-1kh2A:
0.0		 4cx5A-1kh2A:
22.65
4cx5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4cx6A-1kh2A:
0.1
4cx6B-1kh2A:
0.0		 4cx6A-1kh2A:
22.65
4cx6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4cx6A-1kh2A:
0.1
4cx6B-1kh2A:
0.0		 4cx6A-1kh2A:
22.65
4cx6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4d1nA-1kh2A:
0.0
4d1nB-1kh2A:
0.0		 4d1nA-1kh2A:
23.65
4d1nB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4d1nA-1kh2A:
0.0
4d1nB-1kh2A:
0.0		 4d1nA-1kh2A:
23.65
4d1nB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4d1nC-1kh2A:
0.0
4d1nD-1kh2A:
0.0		 4d1nC-1kh2A:
23.65
4d1nD-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4d1nC-1kh2A:
0.0
4d1nD-1kh2A:
0.0		 4d1nC-1kh2A:
23.65
4d1nD-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4d2yA-1kh2A:
0.0
4d2yB-1kh2A:
0.0		 4d2yA-1kh2A:
22.65
4d2yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4d2yA-1kh2A:
0.0
4d2yB-1kh2A:
0.0		 4d2yA-1kh2A:
22.65
4d2yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.37A 4d2zA-1kh2A:
0.2
4d2zB-1kh2A:
0.0		 4d2zA-1kh2A:
22.65
4d2zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4d2zA-1kh2A:
0.2
4d2zB-1kh2A:
0.0		 4d2zA-1kh2A:
22.65
4d2zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4d30A-1kh2A:
0.0
4d30B-1kh2A:
0.1		 4d30A-1kh2A:
22.65
4d30B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4d30A-1kh2A:
0.0
4d30B-1kh2A:
0.1		 4d30A-1kh2A:
22.65
4d30B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4d31A-1kh2A:
0.0
4d31B-1kh2A:
0.0		 4d31A-1kh2A:
22.65
4d31B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4d31A-1kh2A:
0.0
4d31B-1kh2A:
0.0		 4d31A-1kh2A:
22.65
4d31B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 4d32A-1kh2A:
0.0
4d32B-1kh2A:
0.1		 4d32A-1kh2A:
22.65
4d32B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.37A 4d32A-1kh2A:
0.0
4d32B-1kh2A:
0.1		 4d32A-1kh2A:
22.65
4d32B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4d3bA-1kh2A:
0.0
4d3bB-1kh2A:
0.0		 4d3bA-1kh2A:
22.65
4d3bB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4d3bA-1kh2A:
0.0
4d3bB-1kh2A:
0.0		 4d3bA-1kh2A:
22.65
4d3bB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4d7oA-1kh2A:
0.0
4d7oB-1kh2A:
0.0		 4d7oA-1kh2A:
22.65
4d7oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4d7oA-1kh2A:
0.0
4d7oB-1kh2A:
0.0		 4d7oA-1kh2A:
22.65
4d7oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 PHE A 220
ALA A 337
SER A 287
GLY A 274
LEU A 238
 None
 0.84A 4dm8B-1kh2A:
0.0		 4dm8B-1kh2A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4euxA-1kh2A:
0.0
4euxB-1kh2A:
0.2		 4euxA-1kh2A:
22.65
4euxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4euxA-1kh2A:
0.0
4euxB-1kh2A:
0.2		 4euxA-1kh2A:
22.65
4euxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4fvwA-1kh2A:
0.0
4fvwB-1kh2A:
0.1		 4fvwA-1kh2A:
22.65
4fvwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 4fvwA-1kh2A:
0.0
4fvwB-1kh2A:
0.1		 4fvwA-1kh2A:
22.65
4fvwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4fvxA-1kh2A:
0.0
4fvxB-1kh2A:
0.1		 4fvxA-1kh2A:
22.65
4fvxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4fvxA-1kh2A:
0.0
4fvxB-1kh2A:
0.1		 4fvxA-1kh2A:
22.65
4fvxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4fvyA-1kh2A:
0.0
4fvyB-1kh2A:
0.0		 4fvyA-1kh2A:
22.65
4fvyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4fvyA-1kh2A:
0.0
4fvyB-1kh2A:
0.0		 4fvyA-1kh2A:
22.65
4fvyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4fvzA-1kh2A:
0.0
4fvzB-1kh2A:
0.0		 4fvzA-1kh2A:
22.65
4fvzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4fvzA-1kh2A:
0.0
4fvzB-1kh2A:
0.0		 4fvzA-1kh2A:
22.65
4fvzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4fw0A-1kh2A:
0.0
4fw0B-1kh2A:
0.0		 4fw0A-1kh2A:
22.65
4fw0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4fw0A-1kh2A:
0.0
4fw0B-1kh2A:
0.0		 4fw0A-1kh2A:
22.65
4fw0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4gqeA-1kh2A:
0.0
4gqeB-1kh2A:
0.1		 4gqeA-1kh2A:
22.65
4gqeB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4gqeA-1kh2A:
0.0
4gqeB-1kh2A:
0.1		 4gqeA-1kh2A:
22.65
4gqeB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4imtA-1kh2A:
0.6
4imtB-1kh2A:
0.0		 4imtA-1kh2A:
22.65
4imtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.26A 4imtA-1kh2A:
0.6
4imtB-1kh2A:
0.0		 4imtA-1kh2A:
22.65
4imtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4imwA-1kh2A:
0.1
4imwB-1kh2A:
0.1		 4imwA-1kh2A:
22.65
4imwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.27A 4imwA-1kh2A:
0.1
4imwB-1kh2A:
0.1		 4imwA-1kh2A:
22.65
4imwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.39A 4jsfA-1kh2A:
0.1
4jsfB-1kh2A:
0.0		 4jsfA-1kh2A:
22.65
4jsfB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4jsfA-1kh2A:
0.1
4jsfB-1kh2A:
0.0		 4jsfA-1kh2A:
22.65
4jsfB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4jsgA-1kh2A:
0.0
4jsgB-1kh2A:
0.0		 4jsgA-1kh2A:
22.27
4jsgB-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4jsgA-1kh2A:
0.0
4jsgB-1kh2A:
0.0		 4jsgA-1kh2A:
22.27
4jsgB-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4jshA-1kh2A:
0.1
4jshB-1kh2A:
0.1		 4jshA-1kh2A:
22.65
4jshB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4jshA-1kh2A:
0.1
4jshB-1kh2A:
0.1		 4jshA-1kh2A:
22.65
4jshB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 4jsiA-1kh2A:
0.0
4jsiB-1kh2A:
0.5		 4jsiA-1kh2A:
22.65
4jsiB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4jsiA-1kh2A:
0.0
4jsiB-1kh2A:
0.5		 4jsiA-1kh2A:
22.65
4jsiB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4jsjA-1kh2A:
0.0
4jsjB-1kh2A:
0.2		 4jsjA-1kh2A:
22.65
4jsjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4jsjA-1kh2A:
0.0
4jsjB-1kh2A:
0.2		 4jsjA-1kh2A:
22.65
4jsjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4k5dA-1kh2A:
0.6
4k5dB-1kh2A:
0.1		 4k5dA-1kh2A:
22.65
4k5dB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4k5dA-1kh2A:
0.6
4k5dB-1kh2A:
0.1		 4k5dA-1kh2A:
22.65
4k5dB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4k5eA-1kh2A:
0.0
4k5eB-1kh2A:
0.1		 4k5eA-1kh2A:
22.27
4k5eB-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4k5eA-1kh2A:
0.0
4k5eB-1kh2A:
0.1		 4k5eA-1kh2A:
22.27
4k5eB-1kh2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 4k5fA-1kh2A:
0.3
4k5fB-1kh2A:
0.3		 4k5fA-1kh2A:
22.65
4k5fB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4k5fA-1kh2A:
0.3
4k5fB-1kh2A:
0.3		 4k5fA-1kh2A:
22.65
4k5fB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4k5gA-1kh2A:
0.6
4k5gB-1kh2A:
0.0		 4k5gA-1kh2A:
22.65
4k5gB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4k5gA-1kh2A:
0.6
4k5gB-1kh2A:
0.0		 4k5gA-1kh2A:
22.65
4k5gB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4kchA-1kh2A:
0.0
4kchB-1kh2A:
0.1		 4kchA-1kh2A:
22.65
4kchB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4kchA-1kh2A:
0.0
4kchB-1kh2A:
0.1		 4kchA-1kh2A:
22.65
4kchB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4kciA-1kh2A:
0.0
4kciB-1kh2A:
0.1		 4kciA-1kh2A:
22.65
4kciB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 4kciA-1kh2A:
0.0
4kciB-1kh2A:
0.1		 4kciA-1kh2A:
22.65
4kciB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4kcjA-1kh2A:
0.1
4kcjB-1kh2A:
0.0		 4kcjA-1kh2A:
22.65
4kcjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4kcjA-1kh2A:
0.1
4kcjB-1kh2A:
0.0		 4kcjA-1kh2A:
22.65
4kcjB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4kckA-1kh2A:
0.1
4kckB-1kh2A:
0.1		 4kckA-1kh2A:
22.65
4kckB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 4kckA-1kh2A:
0.1
4kckB-1kh2A:
0.1		 4kckA-1kh2A:
22.65
4kckB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4kclA-1kh2A:
0.0
4kclB-1kh2A:
0.0		 4kclA-1kh2A:
22.65
4kclB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4kclA-1kh2A:
0.0
4kclB-1kh2A:
0.0		 4kclA-1kh2A:
22.65
4kclB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4kcmA-1kh2A:
0.0
4kcmB-1kh2A:
0.0		 4kcmA-1kh2A:
22.65
4kcmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4kcmA-1kh2A:
0.0
4kcmB-1kh2A:
0.0		 4kcmA-1kh2A:
22.65
4kcmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4kcnA-1kh2A:
0.0
4kcnB-1kh2A:
0.6		 4kcnA-1kh2A:
22.65
4kcnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4kcnA-1kh2A:
0.0
4kcnB-1kh2A:
0.1		 4kcnA-1kh2A:
22.65
4kcnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 4kcoA-1kh2A:
0.5
4kcoB-1kh2A:
0.0		 4kcoA-1kh2A:
22.65
4kcoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4kcoA-1kh2A:
0.5
4kcoB-1kh2A:
0.0		 4kcoA-1kh2A:
22.65
4kcoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4luxA-1kh2A:
0.6
4luxB-1kh2A:
0.0		 4luxA-1kh2A:
22.65
4luxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4luxA-1kh2A:
0.6
4luxB-1kh2A:
0.0		 4luxA-1kh2A:
22.65
4luxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 LEU A  94
ARG A  92
MET A 174
 None
ATP  A 510 ( 4.1A)
None
 0.93A 4m11C-1kh2A:
0.0		 4m11C-1kh2A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 4uchA-1kh2A:
0.7
4uchB-1kh2A:
0.0		 4uchA-1kh2A:
23.65
4uchB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4uchA-1kh2A:
0.0
4uchB-1kh2A:
0.0		 4uchA-1kh2A:
23.65
4uchB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4ugzA-1kh2A:
0.0
4ugzB-1kh2A:
0.0		 4ugzA-1kh2A:
22.65
4ugzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4ugzA-1kh2A:
0.0
4ugzB-1kh2A:
0.0		 4ugzA-1kh2A:
22.65
4ugzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4uh0A-1kh2A:
0.3
4uh0B-1kh2A:
0.5		 4uh0A-1kh2A:
22.65
4uh0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4uh0A-1kh2A:
0.3
4uh0B-1kh2A:
0.5		 4uh0A-1kh2A:
22.65
4uh0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 4uh1A-1kh2A:
0.0
4uh1B-1kh2A:
1.0		 4uh1A-1kh2A:
22.65
4uh1B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4uh1A-1kh2A:
0.0
4uh1B-1kh2A:
1.0		 4uh1A-1kh2A:
22.65
4uh1B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4uh2A-1kh2A:
0.0
4uh2B-1kh2A:
0.0		 4uh2A-1kh2A:
22.65
4uh2B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4uh2A-1kh2A:
0.0
4uh2B-1kh2A:
0.0		 4uh2A-1kh2A:
22.65
4uh2B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 4uh3A-1kh2A:
0.1
4uh3B-1kh2A:
0.5		 4uh3A-1kh2A:
22.65
4uh3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4uh3A-1kh2A:
0.1
4uh3B-1kh2A:
0.1		 4uh3A-1kh2A:
22.65
4uh3B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4uh4A-1kh2A:
0.0
4uh4B-1kh2A:
0.1		 4uh4A-1kh2A:
22.65
4uh4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 4uh4A-1kh2A:
0.0
4uh4B-1kh2A:
0.1		 4uh4A-1kh2A:
22.65
4uh4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4uh5A-1kh2A:
0.6
4uh5B-1kh2A:
0.0		 4uh5A-1kh2A:
23.65
4uh5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4uh5A-1kh2A:
0.6
4uh5B-1kh2A:
0.0		 4uh5A-1kh2A:
23.65
4uh5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4uh6A-1kh2A:
0.6
4uh6B-1kh2A:
0.1		 4uh6A-1kh2A:
23.65
4uh6B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4uh6A-1kh2A:
0.2
4uh6B-1kh2A:
0.1		 4uh6A-1kh2A:
23.65
4uh6B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4upmA-1kh2A:
0.0
4upmB-1kh2A:
0.5		 4upmA-1kh2A:
22.65
4upmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4upmA-1kh2A:
0.0
4upmB-1kh2A:
0.1		 4upmA-1kh2A:
22.65
4upmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 4upnA-1kh2A:
0.0
4upnB-1kh2A:
0.2		 4upnA-1kh2A:
22.65
4upnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 4upnA-1kh2A:
0.0
4upnB-1kh2A:
0.2		 4upnA-1kh2A:
22.65
4upnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 4upoA-1kh2A:
0.0
4upoB-1kh2A:
0.1		 4upoA-1kh2A:
22.65
4upoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 4upoA-1kh2A:
0.0
4upoB-1kh2A:
0.1		 4upoA-1kh2A:
22.65
4upoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4uppA-1kh2A:
0.0
4uppB-1kh2A:
0.0		 4uppA-1kh2A:
22.65
4uppB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4uppA-1kh2A:
0.0
4uppB-1kh2A:
0.0		 4uppA-1kh2A:
22.65
4uppB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4v3uA-1kh2A:
0.5
4v3uB-1kh2A:
0.0		 4v3uA-1kh2A:
23.65
4v3uB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 4v3uA-1kh2A:
0.6
4v3uB-1kh2A:
0.0		 4v3uA-1kh2A:
23.65
4v3uB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4v3uC-1kh2A:
0.3
4v3uD-1kh2A:
0.0		 4v3uC-1kh2A:
23.65
4v3uD-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 4v3uC-1kh2A:
0.3
4v3uD-1kh2A:
0.0		 4v3uC-1kh2A:
23.65
4v3uD-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 4v3vA-1kh2A:
0.6
4v3vB-1kh2A:
0.0		 4v3vA-1kh2A:
22.65
4v3vB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4v3vA-1kh2A:
0.6
4v3vB-1kh2A:
0.0		 4v3vA-1kh2A:
22.65
4v3vB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.42A 4v3wA-1kh2A:
0.2
4v3wB-1kh2A:
undetectable		 4v3wA-1kh2A:
22.65
4v3wB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 4v3xA-1kh2A:
0.0
4v3xB-1kh2A:
0.1		 4v3xA-1kh2A:
22.65
4v3xB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 4v3xA-1kh2A:
0.0
4v3xB-1kh2A:
0.1		 4v3xA-1kh2A:
22.65
4v3xB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 4v3yA-1kh2A:
0.0
4v3yB-1kh2A:
0.0		 4v3yA-1kh2A:
22.65
4v3yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.36A 4v3yA-1kh2A:
0.0
4v3yB-1kh2A:
0.0		 4v3yA-1kh2A:
22.65
4v3yB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 4v3zA-1kh2A:
0.0
4v3zB-1kh2A:
0.1		 4v3zA-1kh2A:
22.65
4v3zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 4v3zA-1kh2A:
0.0
4v3zB-1kh2A:
0.1		 4v3zA-1kh2A:
22.65
4v3zB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.40A 5ad4A-1kh2A:
0.0
5ad4B-1kh2A:
0.1		 5ad4A-1kh2A:
22.65
5ad4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5ad4A-1kh2A:
0.0
5ad4B-1kh2A:
0.1		 5ad4A-1kh2A:
22.65
5ad4B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5ad5A-1kh2A:
0.0
5ad5B-1kh2A:
0.0		 5ad5A-1kh2A:
22.65
5ad5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5ad5A-1kh2A:
0.0
5ad5B-1kh2A:
0.0		 5ad5A-1kh2A:
22.65
5ad5B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 5ad6A-1kh2A:
0.5
5ad6B-1kh2A:
0.1		 5ad6A-1kh2A:
22.65
5ad6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5ad6A-1kh2A:
0.5
5ad6B-1kh2A:
0.1		 5ad6A-1kh2A:
22.65
5ad6B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5ad7A-1kh2A:
0.0
5ad7B-1kh2A:
0.1		 5ad7A-1kh2A:
22.65
5ad7B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5ad8A-1kh2A:
0.2
5ad8B-1kh2A:
0.1		 5ad8A-1kh2A:
22.65
5ad8B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 5ad9A-1kh2A:
0.0
5ad9B-1kh2A:
0.0		 5ad9A-1kh2A:
22.65
5ad9B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5ad9A-1kh2A:
0.0
5ad9B-1kh2A:
0.0		 5ad9A-1kh2A:
22.65
5ad9B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 5adaA-1kh2A:
0.1
5adaB-1kh2A:
0.0		 5adaA-1kh2A:
22.65
5adaB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5adaA-1kh2A:
0.1
5adaB-1kh2A:
0.0		 5adaA-1kh2A:
22.65
5adaB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5adbA-1kh2A:
0.2
5adbB-1kh2A:
0.0		 5adbA-1kh2A:
22.65
5adbB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5adcA-1kh2A:
0.2
5adcB-1kh2A:
0.0		 5adcA-1kh2A:
22.65
5adcB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.35A 5adcA-1kh2A:
0.2
5adcB-1kh2A:
0.0		 5adcA-1kh2A:
22.65
5adcB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5adfA-1kh2A:
0.5
5adfB-1kh2A:
0.1		 5adfA-1kh2A:
23.65
5adfB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5adgA-1kh2A:
0.3
5adgB-1kh2A:
0.2		 5adgA-1kh2A:
23.65
5adgB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5adgA-1kh2A:
0.3
5adgB-1kh2A:
0.2		 5adgA-1kh2A:
23.65
5adgB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5adiA-1kh2A:
0.0
5adiB-1kh2A:
0.1		 5adiA-1kh2A:
23.65
5adiB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 5agkA-1kh2A:
0.0
5agkB-1kh2A:
0.1		 5agkA-1kh2A:
22.65
5agkB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5agkA-1kh2A:
0.0
5agkB-1kh2A:
0.1		 5agkA-1kh2A:
22.65
5agkB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5aglA-1kh2A:
0.0
5aglB-1kh2A:
0.0		 5aglA-1kh2A:
22.65
5aglB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5aglA-1kh2A:
0.0
5aglB-1kh2A:
0.0		 5aglA-1kh2A:
22.65
5aglB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5agmA-1kh2A:
0.0
5agmB-1kh2A:
0.1		 5agmA-1kh2A:
22.65
5agmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 5agmA-1kh2A:
0.0
5agmB-1kh2A:
0.1		 5agmA-1kh2A:
22.65
5agmB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5agnA-1kh2A:
0.0
5agnB-1kh2A:
0.0		 5agnA-1kh2A:
22.65
5agnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 5agnA-1kh2A:
0.0
5agnB-1kh2A:
0.0		 5agnA-1kh2A:
22.65
5agnB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5agoA-1kh2A:
0.0
5agoB-1kh2A:
0.0		 5agoA-1kh2A:
22.65
5agoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5agoA-1kh2A:
0.0
5agoB-1kh2A:
0.0		 5agoA-1kh2A:
22.65
5agoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5agpA-1kh2A:
0.0
5agpB-1kh2A:
0.0		 5agpA-1kh2A:
22.65
5agpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5agpA-1kh2A:
0.0
5agpB-1kh2A:
0.0		 5agpA-1kh2A:
22.65
5agpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.38A 5fvpA-1kh2A:
0.4
5fvpB-1kh2A:
0.1		 5fvpA-1kh2A:
22.65
5fvpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5fvpA-1kh2A:
0.4
5fvpB-1kh2A:
0.1		 5fvpA-1kh2A:
22.65
5fvpB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5fvqA-1kh2A:
0.0
5fvqB-1kh2A:
0.1		 5fvqA-1kh2A:
22.65
5fvqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5fvqA-1kh2A:
0.0
5fvqB-1kh2A:
0.1		 5fvqA-1kh2A:
22.65
5fvqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5fvrA-1kh2A:
0.0
5fvrB-1kh2A:
0.0		 5fvrA-1kh2A:
22.65
5fvrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5fvrA-1kh2A:
0.0
5fvrB-1kh2A:
0.0		 5fvrA-1kh2A:
22.65
5fvrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5fvsA-1kh2A:
0.0
5fvsB-1kh2A:
0.0		 5fvsA-1kh2A:
22.65
5fvsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5fvsA-1kh2A:
0.0
5fvsB-1kh2A:
0.0		 5fvsA-1kh2A:
22.65
5fvsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5fvtA-1kh2A:
0.0
5fvtB-1kh2A:
0.0		 5fvtA-1kh2A:
22.65
5fvtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5fvtA-1kh2A:
0.0
5fvtB-1kh2A:
0.0		 5fvtA-1kh2A:
22.65
5fvtB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5fvuA-1kh2A:
0.2
5fvuB-1kh2A:
0.1		 5fvuA-1kh2A:
23.65
5fvuB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 5fvuA-1kh2A:
0.2
5fvuB-1kh2A:
0.1		 5fvuA-1kh2A:
23.65
5fvuB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5fvvA-1kh2A:
0.5
5fvvB-1kh2A:
0.7		 5fvvA-1kh2A:
23.65
5fvvB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 5fvvA-1kh2A:
0.4
5fvvB-1kh2A:
0.7		 5fvvA-1kh2A:
23.65
5fvvB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5fvwA-1kh2A:
0.1
5fvwB-1kh2A:
0.7		 5fvwA-1kh2A:
23.65
5fvwB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5fvwA-1kh2A:
0.4
5fvwB-1kh2A:
0.7		 5fvwA-1kh2A:
23.65
5fvwB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5fvxA-1kh2A:
0.6
5fvxB-1kh2A:
0.3		 5fvxA-1kh2A:
23.65
5fvxB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5fw0A-1kh2A:
0.1
5fw0B-1kh2A:
0.1		 5fw0A-1kh2A:
22.65
5fw0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5fw0A-1kh2A:
0.1
5fw0B-1kh2A:
0.1		 5fw0A-1kh2A:
22.65
5fw0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5g0nA-1kh2A:
0.0
5g0nB-1kh2A:
0.0		 5g0nA-1kh2A:
22.65
5g0nB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5g0nA-1kh2A:
0.0
5g0nB-1kh2A:
0.0		 5g0nA-1kh2A:
22.65
5g0nB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5g0oA-1kh2A:
0.2
5g0oB-1kh2A:
0.0		 5g0oA-1kh2A:
22.65
5g0oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5g0oA-1kh2A:
0.2
5g0oB-1kh2A:
0.0		 5g0oA-1kh2A:
22.65
5g0oB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5g0pA-1kh2A:
undetectable
5g0pB-1kh2A:
undetectable		 5g0pA-1kh2A:
22.65
5g0pB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 TRP A 145
TRP A  19
GLU A 144
HIS A 113
 None
 1.31A 5hqaA-1kh2A:
undetectable		 5hqaA-1kh2A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 THR A 289
ALA A 353
GLY A 335
ALA A 337
LEU A 242
 None
 1.08A 5lf7H-1kh2A:
undetectable
5lf7I-1kh2A:
undetectable		 5lf7H-1kh2A:
19.51
5lf7I-1kh2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 THR A 289
ALA A 353
GLY A 335
ALA A 337
LEU A 242
 None
 1.08A 5lf7V-1kh2A:
undetectable
5lf7W-1kh2A:
undetectable		 5lf7V-1kh2A:
19.51
5lf7W-1kh2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 PHE A 220
ALA A 337
SER A 287
GLY A 274
LEU A 238
 None
 0.85A 5m24A-1kh2A:
0.0		 5m24A-1kh2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 PHE A 220
ALA A 337
SER A 287
GLY A 275
LEU A 238
 None
 0.94A 5m24A-1kh2A:
0.0		 5m24A-1kh2A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 242
ASN A 243
GLY A 246
GLY A 247
LEU A 339
 None
 0.78A 5uc1B-1kh2A:
undetectable		 5uc1B-1kh2A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5unrA-1kh2A:
0.1
5unrB-1kh2A:
0.0		 5unrA-1kh2A:
22.65
5unrB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5unsA-1kh2A:
0.1
5unsB-1kh2A:
0.0		 5unsA-1kh2A:
22.65
5unsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5unsA-1kh2A:
0.1
5unsB-1kh2A:
0.0		 5unsA-1kh2A:
22.65
5unsB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.37A 5untA-1kh2A:
0.2
5untB-1kh2A:
0.1		 5untA-1kh2A:
22.65
5untB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5untA-1kh2A:
0.2
5untB-1kh2A:
0.1		 5untA-1kh2A:
22.65
5untB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5unuA-1kh2A:
0.1
5unuB-1kh2A:
0.1		 5unuA-1kh2A:
22.65
5unuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5unuA-1kh2A:
0.1
5unuB-1kh2A:
0.1		 5unuA-1kh2A:
22.65
5unuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.44A 5unvA-1kh2A:
0.1
5unvB-1kh2A:
0.1		 5unvA-1kh2A:
22.65
5unvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.37A 5unvA-1kh2A:
0.1
5unvB-1kh2A:
0.1		 5unvA-1kh2A:
22.65
5unvB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5unwA-1kh2A:
0.6
5unwB-1kh2A:
0.0		 5unwA-1kh2A:
22.65
5unwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5unwA-1kh2A:
0.6
5unwB-1kh2A:
0.0		 5unwA-1kh2A:
22.65
5unwB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 5unxA-1kh2A:
0.4
5unxB-1kh2A:
0.1		 5unxA-1kh2A:
22.65
5unxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5unxA-1kh2A:
0.4
5unxB-1kh2A:
0.1		 5unxA-1kh2A:
22.65
5unxB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5unyA-1kh2A:
0.0
5unyB-1kh2A:
0.0		 5unyA-1kh2A:
22.65
5unyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5unyA-1kh2A:
0.0
5unyB-1kh2A:
0.0		 5unyA-1kh2A:
22.65
5unyB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5unzA-1kh2A:
0.0
5unzB-1kh2A:
0.1		 5unzA-1kh2A:
22.65
5unzB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5uo0A-1kh2A:
0.3
5uo0B-1kh2A:
0.1		 5uo0A-1kh2A:
22.65
5uo0B-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5uo1A-1kh2A:
0.2
5uo1B-1kh2A:
0.2		 5uo1A-1kh2A:
23.65
5uo1B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5uo1A-1kh2A:
0.6
5uo1B-1kh2A:
0.2		 5uo1A-1kh2A:
23.65
5uo1B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5uo2A-1kh2A:
0.0
5uo2B-1kh2A:
0.2		 5uo2A-1kh2A:
23.65
5uo2B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5uo2A-1kh2A:
0.6
5uo2B-1kh2A:
0.2		 5uo2A-1kh2A:
23.65
5uo2B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5uo3A-1kh2A:
0.2
5uo3B-1kh2A:
0.0		 5uo3A-1kh2A:
23.65
5uo3B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5uo3A-1kh2A:
0.2
5uo3B-1kh2A:
0.0		 5uo3A-1kh2A:
23.65
5uo3B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5uo4A-1kh2A:
0.2
5uo4B-1kh2A:
0.0		 5uo4A-1kh2A:
23.65
5uo4B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5uo4A-1kh2A:
0.2
5uo4B-1kh2A:
0.0		 5uo4A-1kh2A:
23.65
5uo4B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5uo5A-1kh2A:
0.5
5uo5B-1kh2A:
0.4		 5uo5A-1kh2A:
23.65
5uo5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5uo5A-1kh2A:
0.5
5uo5B-1kh2A:
0.4		 5uo5A-1kh2A:
23.65
5uo5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5uo6A-1kh2A:
0.5
5uo6B-1kh2A:
0.1		 5uo6A-1kh2A:
23.65
5uo6B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 8 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 5uo7A-1kh2A:
0.1
5uo7B-1kh2A:
0.1		 5uo7A-1kh2A:
23.65
5uo7B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5uo7A-1kh2A:
0.1
5uo7B-1kh2A:
0.6		 5uo7A-1kh2A:
23.65
5uo7B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5vuiA-1kh2A:
0.3
5vuiB-1kh2A:
0.1		 5vuiA-1kh2A:
22.65
5vuiB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vuiA-1kh2A:
0.3
5vuiB-1kh2A:
0.1		 5vuiA-1kh2A:
22.65
5vuiB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.45A 5vujA-1kh2A:
0.3
5vujB-1kh2A:
0.5		 5vujA-1kh2A:
22.65
5vujB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.41A 5vujA-1kh2A:
0.3
5vujB-1kh2A:
0.5		 5vujA-1kh2A:
22.65
5vujB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.37A 5vukA-1kh2A:
0.1
5vukB-1kh2A:
0.1		 5vukA-1kh2A:
22.65
5vukB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5vukA-1kh2A:
0.1
5vukB-1kh2A:
0.1		 5vukA-1kh2A:
22.65
5vukB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5vulA-1kh2A:
0.1
5vulB-1kh2A:
0.0		 5vulA-1kh2A:
22.65
5vulB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5vulA-1kh2A:
0.1
5vulB-1kh2A:
0.0		 5vulA-1kh2A:
22.65
5vulB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 5vumA-1kh2A:
0.2
5vumB-1kh2A:
0.0		 5vumA-1kh2A:
22.65
5vumB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5vumA-1kh2A:
0.2
5vumB-1kh2A:
0.0		 5vumA-1kh2A:
22.65
5vumB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vunA-1kh2A:
0.0
5vunB-1kh2A:
0.0		 5vunA-1kh2A:
22.65
5vunB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5vunA-1kh2A:
0.0
5vunB-1kh2A:
0.0		 5vunA-1kh2A:
22.65
5vunB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vuoA-1kh2A:
0.1
5vuoB-1kh2A:
0.0		 5vuoA-1kh2A:
22.65
5vuoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5vuoA-1kh2A:
0.1
5vuoB-1kh2A:
0.0		 5vuoA-1kh2A:
22.65
5vuoB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5vupA-1kh2A:
0.0
5vupB-1kh2A:
0.1		 5vupA-1kh2A:
22.65
5vupB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vupA-1kh2A:
0.0
5vupB-1kh2A:
0.1		 5vupA-1kh2A:
22.65
5vupB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vuqA-1kh2A:
0.0
5vuqB-1kh2A:
0.0		 5vuqA-1kh2A:
22.65
5vuqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vuqA-1kh2A:
0.0
5vuqB-1kh2A:
0.0		 5vuqA-1kh2A:
22.65
5vuqB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.34A 5vurA-1kh2A:
0.3
5vurB-1kh2A:
0.0		 5vurA-1kh2A:
22.65
5vurB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vusA-1kh2A:
0.3
5vusB-1kh2A:
0.1		 5vusA-1kh2A:
22.65
5vusB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vusA-1kh2A:
0.3
5vusB-1kh2A:
0.1		 5vusA-1kh2A:
22.65
5vusB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vutA-1kh2A:
0.0
5vutB-1kh2A:
0.0		 5vutA-1kh2A:
22.65
5vutB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5vutA-1kh2A:
0.0
5vutB-1kh2A:
0.0		 5vutA-1kh2A:
22.65
5vutB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5vuuA-1kh2A:
0.3
5vuuB-1kh2A:
0.0		 5vuuA-1kh2A:
22.65
5vuuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 5vuuA-1kh2A:
0.3
5vuuB-1kh2A:
0.0		 5vuuA-1kh2A:
22.65
5vuuB-1kh2A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.28A 5vuvA-1kh2A:
0.0
5vuvB-1kh2A:
0.6		 5vuvA-1kh2A:
23.65
5vuvB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5vuvA-1kh2A:
0.0
5vuvB-1kh2A:
0.6		 5vuvA-1kh2A:
23.65
5vuvB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vuwA-1kh2A:
0.0
5vuwB-1kh2A:
0.0		 5vuwA-1kh2A:
23.65
5vuwB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vuwA-1kh2A:
0.6
5vuwB-1kh2A:
0.0		 5vuwA-1kh2A:
23.65
5vuwB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vuxA-1kh2A:
0.0
5vuxB-1kh2A:
0.8		 5vuxA-1kh2A:
23.65
5vuxB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.36A 5vuyA-1kh2A:
0.0
5vuyB-1kh2A:
0.0		 5vuyA-1kh2A:
23.65
5vuyB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.24A 5vuyA-1kh2A:
0.0
5vuyB-1kh2A:
0.0		 5vuyA-1kh2A:
23.65
5vuyB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 5vuzA-1kh2A:
0.6
5vuzB-1kh2A:
0.0		 5vuzA-1kh2A:
23.65
5vuzB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 5vuzA-1kh2A:
0.6
5vuzB-1kh2A:
0.0		 5vuzA-1kh2A:
23.65
5vuzB-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 5vv0A-1kh2A:
0.3
5vv0B-1kh2A:
0.0		 5vv0A-1kh2A:
23.65
5vv0B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.32A 5vv0A-1kh2A:
0.3
5vv0B-1kh2A:
0.0		 5vv0A-1kh2A:
23.65
5vv0B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 5vv1A-1kh2A:
0.0
5vv1B-1kh2A:
0.1		 5vv1A-1kh2A:
23.65
5vv1B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5vv1A-1kh2A:
0.0
5vv1B-1kh2A:
0.1		 5vv1A-1kh2A:
23.65
5vv1B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.34A 5vv2A-1kh2A:
0.5
5vv2B-1kh2A:
0.0		 5vv2A-1kh2A:
23.65
5vv2B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 5vv2A-1kh2A:
0.5
5vv2B-1kh2A:
0.0		 5vv2A-1kh2A:
23.65
5vv2B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5vv3A-1kh2A:
0.3
5vv3B-1kh2A:
0.8		 5vv3A-1kh2A:
23.65
5vv3B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 5vv3A-1kh2A:
0.3
5vv3B-1kh2A:
0.8		 5vv3A-1kh2A:
23.65
5vv3B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 5vv4A-1kh2A:
0.2
5vv4B-1kh2A:
0.1		 5vv4A-1kh2A:
23.65
5vv4B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 5vv5A-1kh2A:
0.1
5vv5B-1kh2A:
0.1		 5vv5A-1kh2A:
23.65
5vv5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.36A 5vv5A-1kh2A:
0.1
5vv5B-1kh2A:
0.1		 5vv5A-1kh2A:
23.65
5vv5B-1kh2A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A  99
ALA A 112
THR A  51
ALA A  53
ILE A  29
 None
 0.91A 5xiwB-1kh2A:
undetectable		 5xiwB-1kh2A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.35A 6auqA-1kh2A:
0.1
6auqB-1kh2A:
0.1		 6auqA-1kh2A:
10.75
6auqB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 6auqA-1kh2A:
0.1
6auqB-1kh2A:
0.1		 6auqA-1kh2A:
10.75
6auqB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.29A 6aurA-1kh2A:
0.0
6aurB-1kh2A:
0.1		 6aurA-1kh2A:
10.75
6aurB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6aurA-1kh2A:
0.0
6aurB-1kh2A:
0.1		 6aurA-1kh2A:
10.75
6aurB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 6ausA-1kh2A:
0.0
6ausB-1kh2A:
0.0		 6ausA-1kh2A:
10.75
6ausB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6ausA-1kh2A:
0.0
6ausB-1kh2A:
0.0		 6ausA-1kh2A:
10.75
6ausB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 6autA-1kh2A:
0.0
6autB-1kh2A:
0.0		 6autA-1kh2A:
10.75
6autB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6autA-1kh2A:
0.0
6autB-1kh2A:
0.0		 6autA-1kh2A:
10.75
6autB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6auuA-1kh2A:
0.3
6auuB-1kh2A:
0.0		 6auuA-1kh2A:
10.75
6auuB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 6auuA-1kh2A:
0.3
6auuB-1kh2A:
0.0		 6auuA-1kh2A:
10.75
6auuB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6auvA-1kh2A:
0.0
6auvB-1kh2A:
0.5		 6auvA-1kh2A:
10.75
6auvB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6auvA-1kh2A:
0.0
6auvB-1kh2A:
0.5		 6auvA-1kh2A:
10.75
6auvB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 6auwA-1kh2A:
0.5
6auwB-1kh2A:
0.0		 6auwA-1kh2A:
10.75
6auwB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6auwA-1kh2A:
0.5
6auwB-1kh2A:
0.0		 6auwA-1kh2A:
10.75
6auwB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 6auxA-1kh2A:
0.0
6auxB-1kh2A:
0.1		 6auxA-1kh2A:
10.75
6auxB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6auxA-1kh2A:
0.0
6auxB-1kh2A:
0.1		 6auxA-1kh2A:
10.75
6auxB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6auyA-1kh2A:
0.5
6auyB-1kh2A:
0.1		 6auyA-1kh2A:
10.75
6auyB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 6auyA-1kh2A:
0.5
6auyB-1kh2A:
0.1		 6auyA-1kh2A:
10.75
6auyB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.33A 6auzA-1kh2A:
0.5
6auzB-1kh2A:
0.4		 6auzA-1kh2A:
10.75
6auzB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 6auzA-1kh2A:
0.5
6auzB-1kh2A:
0.4		 6auzA-1kh2A:
10.75
6auzB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 6av0A-1kh2A:
0.3
6av0B-1kh2A:
0.1		 6av0A-1kh2A:
10.75
6av0B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 6av0A-1kh2A:
0.6
6av0B-1kh2A:
0.1		 6av0A-1kh2A:
10.75
6av0B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6av1A-1kh2A:
0.5
6av1B-1kh2A:
0.0		 6av1A-1kh2A:
10.75
6av1B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.33A 6av1A-1kh2A:
0.5
6av1B-1kh2A:
0.0		 6av1A-1kh2A:
10.75
6av1B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6av2A-1kh2A:
0.2
6av2B-1kh2A:
0.1		 6av2A-1kh2A:
10.75
6av2B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.29A 6av2A-1kh2A:
0.2
6av2B-1kh2A:
0.1		 6av2A-1kh2A:
10.75
6av2B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 6av3A-1kh2A:
0.2
6av3B-1kh2A:
0.1		 6av3A-1kh2A:
10.75
6av3B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.30A 6av3A-1kh2A:
0.2
6av3B-1kh2A:
0.1		 6av3A-1kh2A:
10.75
6av3B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.31A 6av4A-1kh2A:
0.0
6av4B-1kh2A:
0.0		 6av4A-1kh2A:
10.75
6av4B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6av4A-1kh2A:
0.0
6av4B-1kh2A:
0.0		 6av4A-1kh2A:
10.75
6av4B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6av5A-1kh2A:
0.2
6av5B-1kh2A:
0.0		 6av5A-1kh2A:
10.75
6av5B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.28A 6av5A-1kh2A:
0.2
6av5B-1kh2A:
0.0		 6av5A-1kh2A:
10.75
6av5B-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 10 ARG A  92
PHE A 125
ALA A 115
GLY A 114
ILE A 111
 ATP  A 510 ( 4.1A)
ATP  A 510 (-3.9A)
ATP  A 510 (-4.3A)
ATP  A 510 (-3.1A)
None
 0.99A 6bniA-1kh2A:
undetectable		 6bniA-1kh2A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		5 / 10 ARG A  92
PHE A 125
ALA A 115
GLY A 114
ILE A 111
 ATP  A 510 ( 4.1A)
ATP  A 510 (-3.9A)
ATP  A 510 (-4.3A)
ATP  A 510 (-3.1A)
None
 1.01A 6bniB-1kh2A:
undetectable		 6bniB-1kh2A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.32A 6cicA-1kh2A:
0.5
6cicB-1kh2A:
0.1		 6cicA-1kh2A:
10.75
6cicB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6cicA-1kh2A:
0.5
6cicB-1kh2A:
0.1		 6cicA-1kh2A:
10.75
6cicB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 ARG A 282
VAL A 226
PHE A 220
GLU A 222
 None
 1.30A 6cidA-1kh2A:
0.3
6cidB-1kh2A:
0.0		 6cidA-1kh2A:
10.75
6cidB-1kh2A:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1kh2 ARGININOSUCCINATE
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 PHE A 220
GLU A 222
ARG A 282
VAL A 226
 None
 1.31A 6cidA-1kh2A:
0.3
6cidB-1kh2A:
0.0		 6cidA-1kh2A:
10.75
6cidB-1kh2A:
10.75