SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1khd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 9 ILE A 254
LEU A 312
VAL A 229
ALA A 216
LEU A 219
 None
 1.15A 1e7bA-1khdA:
0.3		 1e7bA-1khdA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 LEU A 249
LEU A 213
ALA A 216
LYS A 220
 None
 0.56A 1e7cA-1khdA:
undetectable		 1e7cA-1khdA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 GLN A  33
ILE A 194
HIS A 168
 None
 0.62A 1fm9A-1khdA:
undetectable		 1fm9A-1khdA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 11 PHE A  35
ALA A  68
VAL A 229
LEU A 219
GLN A 217
 None
 1.33A 1hbpA-1khdA:
undetectable		 1hbpA-1khdA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 10 LEU A  20
GLU A  60
LEU A  48
ALA A  50
LEU A  43
 None
 1.30A 1ie4A-1khdA:
0.0
1ie4C-1khdA:
0.0		 1ie4A-1khdA:
16.67
1ie4C-1khdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 GLN A  33
ILE A 194
HIS A 168
 None
 0.60A 1k74A-1khdA:
undetectable		 1k74A-1khdA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_1
(PROTEIN (METHIONINE
REPRESSOR))		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 4 HIS A  32
ALA A  71
PHE A  35
GLY A  67
 None
 1.35A 1mj2D-1khdA:
undetectable		 1mj2D-1khdA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 GLY A  67
ALA A  68
ILE A  38
ILE A  16
ILE A 186
 None
 0.85A 1muiB-1khdA:
undetectable		 1muiB-1khdA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 VAL A 306
GLY A 332
THR A 333
ALA A 334
 None
 0.87A 2a1hA-1khdA:
undetectable
2a1hB-1khdA:
undetectable		 2a1hA-1khdA:
22.63
2a1hB-1khdA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 LEU A 190
ILE A 194
PHE A 171
ILE A  38
 None
 0.87A 2azxA-1khdA:
undetectable		 2azxA-1khdA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 ILE A 186
ALA A  68
LEU A  34
SER A  31
LEU A  48
 None
 1.15A 2h77A-1khdA:
0.0		 2h77A-1khdA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 7 SER A 106
ALA A 107
SER A 103
ASN A 101
 None
 1.00A 2i91A-1khdA:
2.9		 2i91A-1khdA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 7 SER A 106
ALA A 107
SER A 103
ASN A 101
 None
 1.00A 2i91B-1khdA:
2.9		 2i91B-1khdA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 LEU A 135
LEU A 136
PHE A 139
PHE A 335
 None
 0.88A 2vctC-1khdA:
2.1		 2vctC-1khdA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 ARG A  61
GLY A  59
SER A 208
 None
 0.58A 2xctB-1khdA:
undetectable		 2xctB-1khdA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 7 ARG A 123
GLY A  93
VAL A  90
ASP A  95
 None
 0.90A 2y05A-1khdA:
3.3
2y05B-1khdA:
3.5		 2y05A-1khdA:
22.40
2y05B-1khdA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 VAL A 159
ALA A 153
ALA A 197
VAL A 338
ILE A 141
 None
 1.10A 3czhA-1khdA:
0.0		 3czhA-1khdA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 ASN A 122
MET A 145
PHE A 161
 None
 1.02A 3g4lD-1khdA:
undetectable		 3g4lD-1khdA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 GLY A 191
ALA A  66
GLY A  67
LEU A  72
ILE A 194
 None
 0.81A 3ku1A-1khdA:
2.9		 3ku1A-1khdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 GLY A 191
ALA A  66
GLY A  67
LEU A  72
ILE A 194
 None
 0.80A 3ku1C-1khdA:
undetectable		 3ku1C-1khdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 11 LEU A 249
ALA A 202
ASP A  88
GLY A 205
VAL A 206
 None
 1.24A 3oxxB-1khdA:
0.0		 3oxxB-1khdA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 ILE A  38
GLU A  60
THR A 185
LEU A 190
 None
 0.85A 3ua5A-1khdA:
undetectable		 3ua5A-1khdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 7 ALA A  68
GLY A  67
ILE A  65
ILE A 186
 None
 0.67A 4eatA-1khdA:
undetectable		 4eatA-1khdA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 LEU A 219
LEU A 222
ILE A 204
HIS A 168
 None
 0.69A 4klaA-1khdA:
undetectable		 4klaA-1khdA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 LEU A 181
LYS A 182
THR A 183
 None
 0.49A 4lj0A-1khdA:
0.0		 4lj0A-1khdA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 MET A  26
GLU A  30
LEU A  34
 None
 0.76A 4v2oB-1khdA:
0.0		 4v2oB-1khdA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 4 ASN A 195
SER A 150
ALA A 118
VAL A 117
 None
 1.00A 4x1kC-1khdA:
2.2		 4x1kC-1khdA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 LEU A 286
ASP A 295
GLY A 294
ALA A 334
VAL A 302
 None
 1.33A 5kbwB-1khdA:
0.0		 5kbwB-1khdA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 GLU A  64
LEU A  72
ALA A  68
SER A  31
LEU A  52
 None
 1.15A 5m5cB-1khdA:
undetectable		 5m5cB-1khdA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		4 / 8 ALA A 216
ILE A  65
ALA A  66
LEU A 193
 None
 0.82A 5te8B-1khdA:
0.0		 5te8B-1khdA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 GLY A 294
LEU A 289
HIS A 298
 None
 0.60A 5u63A-1khdA:
3.1		 5u63A-1khdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 GLY A 294
LEU A 289
HIS A 298
 None
 0.59A 5u63B-1khdA:
3.2		 5u63B-1khdA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		3 / 3 GLN A  33
ILE A 194
HIS A 168
 None
 0.53A 5z12B-1khdA:
undetectable		 5z12B-1khdA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 ALA A 197
PRO A  78
ALA A 118
PRO A  82
TYR A  84
 None
 1.06A 5zvgA-1khdA:
undetectable		 5zvgA-1khdA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE
(Pectobacterium
carotovorum) 		5 / 12 ALA A 197
PRO A  78
ALA A 118
PRO A  82
TYR A  84
 None
 1.06A 5zvgB-1khdA:
undetectable		 5zvgB-1khdA:
20.34