SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kht'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		5 / 10 GLY A  10
HIS A 151
ALA A 159
THR A   9
ALA A 158
 None
 1.45A 1gtnO-1khtA:
undetectable
1gtnP-1khtA:
undetectable		 1gtnO-1khtA:
15.71
1gtnP-1khtA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		3 / 3 SER A  20
VAL A 190
LEU A 191
 None
 0.49A 1yajG-1khtA:
undetectable		 1yajG-1khtA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		4 / 5 THR A  17
SER A  38
ASP A  90
SER A  41
 None
 1.02A 2hdnA-1khtA:
0.0
2hdnB-1khtA:
3.0
2hdnD-1khtA:
3.9		 2hdnA-1khtA:
11.92
2hdnB-1khtA:
19.83
2hdnD-1khtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		4 / 5 SER A  41
THR A  17
SER A  38
ASP A  90
 None
 1.08A 2hdnB-1khtA:
3.0
2hdnC-1khtA:
0.0
2hdnD-1khtA:
3.9		 2hdnB-1khtA:
19.83
2hdnC-1khtA:
11.92
2hdnD-1khtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		4 / 6 THR A  17
SER A  38
ASP A  90
SER A  41
 None
 1.04A 2hdnI-1khtA:
0.0
2hdnJ-1khtA:
2.9
2hdnL-1khtA:
3.0		 2hdnI-1khtA:
11.92
2hdnJ-1khtA:
19.83
2hdnL-1khtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		4 / 6 SER A  41
THR A  17
SER A  38
ASP A  90
 None
 1.11A 2hdnJ-1khtA:
3.9
2hdnK-1khtA:
0.0
2hdnL-1khtA:
3.0		 2hdnJ-1khtA:
19.83
2hdnK-1khtA:
11.92
2hdnL-1khtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1kht ADENYLATE KINASE
(Methanococcus
voltae) 		6 / 12 LEU A 117
ALA A 159
GLY A  10
VAL A 121
VAL A   6
ILE A 118
 None
 1.40A 2o4lB-1khtA:
undetectable		 2o4lB-1khtA:
22.68