SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1khy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 11 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.94A 1g50A-1khyA:
undetectable		 1g50A-1khyA:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 10 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.87A 1gwrA-1khyA:
0.7		 1gwrA-1khyA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A  38
LEU A 113
ALA A 114
LEU A  93
LEU A   6
 None
 1.19A 1s9pB-1khyA:
undetectable		 1s9pB-1khyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.94A 1s9pC-1khyA:
undetectable		 1s9pC-1khyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 1khy CLPB PROTEIN
(Escherichia
coli) 		4 / 4 LEU A 122
THR A 121
ILE A  29
HIS A  33
 None
 1.30A 2jfaB-1khyA:
undetectable		 2jfaB-1khyA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.87A 3olsA-1khyA:
undetectable		 3olsA-1khyA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.88A 3q95B-1khyA:
undetectable		 3q95B-1khyA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 ALA A  37
LEU A  39
LEU A  60
LEU A 126
LEU A  32
 None
 1.13A 3r9cA-1khyA:
0.0		 3r9cA-1khyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.92A 4pxmA-1khyA:
undetectable		 4pxmA-1khyA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 1khy CLPB PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 110
LEU A 113
ALA A 114
GLU A 117
LEU A  93
 None
 0.92A 5toaA-1khyA:
undetectable		 5toaA-1khyA:
21.95