SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ki9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 ILE A 119
ILE A 173
THR A 169
 None
 0.60A 1rg7A-1ki9A:
2.4		 1rg7A-1ki9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_B_ADNB1_1
(UNCHARACTERIZED
PROTEIN)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		5 / 9 ARG A 138
ILE A  95
ASN A 155
HIS A 151
THR A  97
 None
 1.49A 3oi8A-1ki9A:
undetectable
3oi8B-1ki9A:
undetectable		 3oi8A-1ki9A:
20.41
3oi8B-1ki9A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 LEU A  62
ILE A  70
ARG A  69
 None
 0.55A 4mk4B-1ki9A:
3.3		 4mk4B-1ki9A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		4 / 6 GLY A  16
THR A  17
VAL A   8
HIS A  92
 None
 1.14A 5ewuB-1ki9A:
undetectable		 5ewuB-1ki9A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.02A 5ewzB-1ki9A:
undetectable		 5ewzB-1ki9A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.02A 5m35B-1ki9A:
0.2		 5m35B-1ki9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.02A 5m36A-1ki9A:
0.2		 5m36A-1ki9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.05A 6fn9A-1ki9A:
0.1		 6fn9A-1ki9A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.03A 6fnaB-1ki9A:
0.2		 6fnaB-1ki9A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1ki9 ADENYLATE KINASE
(Methanothermococ
cus
thermolithotroph
icus) 		3 / 3 MET A  59
GLN A  58
ARG A  60
 None
 1.04A 6fnbA-1ki9A:
0.1		 6fnbA-1ki9A:
23.69