SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		3 / 3 GLU A  37
ALA A  53
SER A  56
 EDO  A 401 (-2.9A)
None
MPO  A 400 (-3.8A)
 0.59A 1errB-1kj9A:
0.0		 1errB-1kj9A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 12 LEU A  67
MET A  61
LEU A  62
ILE A  83
GLY A  19
 None
None
None
CL  A 399 ( 4.4A)
None
 1.25A 1g50B-1kj9A:
undetectable		 1g50B-1kj9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 11 LEU A  67
MET A  61
LEU A  62
ILE A  83
GLY A  19
 None
None
None
CL  A 399 ( 4.4A)
None
 1.24A 1g50C-1kj9A:
0.0		 1g50C-1kj9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 11 VAL A  70
VAL A  41
GLU A  72
LEU A  99
ILE A  79
 None
 1.46A 1t6zA-1kj9A:
3.8		 1t6zA-1kj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 11 VAL A  70
VAL A  41
GLU A  72
LEU A  99
ILE A  79
 None
 1.35A 1t6zB-1kj9A:
2.2		 1t6zB-1kj9A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 10 LEU A 308
PHE A 307
LEU A  34
ARG A  33
ALA A 301
 None
 1.06A 2bxeB-1kj9A:
undetectable		 2bxeB-1kj9A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 10 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.93A 2f16K-1kj9A:
undetectable
2f16L-1kj9A:
undetectable		 2f16K-1kj9A:
20.71
2f16L-1kj9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 10 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.94A 2f16Y-1kj9A:
undetectable
2f16Z-1kj9A:
undetectable		 2f16Y-1kj9A:
20.71
2f16Z-1kj9A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 GLN A 349
ILE A 326
VAL A 388
VAL A 340
 None
 0.65A 3fi0Q-1kj9A:
undetectable		 3fi0Q-1kj9A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 12 VAL A  52
LEU A 292
ARG A 363
GLY A 354
LEU A 352
 None
None
MG  A 395 ( 4.9A)
None
None
 1.26A 3j6pB-1kj9A:
0.0		 3j6pB-1kj9A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 9 LEU A 127
PHE A 277
LEU A 258
ILE A 117
ALA A 257
 None
 1.08A 3mdvA-1kj9A:
0.0		 3mdvA-1kj9A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		3 / 3 GLN A 165
GLU A 195
LYS A 155
 ATP  A   1 (-3.4A)
ATP  A   1 (-4.0A)
ATP  A   1 (-2.8A)
 1.15A 3su9A-1kj9A:
undetectable		 3su9A-1kj9A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 12 ASP A 213
ILE A 315
GLY A 214
VAL A 312
LEU A 263
 None
 1.02A 3uq6A-1kj9A:
3.3		 3uq6A-1kj9A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 12 ASP A 213
ILE A 315
GLY A 214
VAL A 312
LEU A 263
 None
 1.02A 3vaqA-1kj9A:
3.7		 3vaqA-1kj9A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 12 ASP A 213
ILE A 315
GLY A 214
VAL A 312
LEU A 263
 None
 1.01A 3vasA-1kj9A:
3.6		 3vasA-1kj9A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 6 VAL A  36
LEU A   4
TYR A  78
VAL A 304
 None
 0.89A 4a9kA-1kj9A:
0.0		 4a9kA-1kj9A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 PHE A 200
VAL A 198
ILE A 276
ALA A 243
 ATP  A   1 (-4.9A)
ATP  A   1 (-3.9A)
None
None
 1.01A 4eyzA-1kj9A:
undetectable		 4eyzA-1kj9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 PHE A 200
VAL A 198
ILE A 276
ALA A 247
 ATP  A   1 (-4.9A)
ATP  A   1 (-3.9A)
None
None
 0.99A 4eyzA-1kj9A:
undetectable		 4eyzA-1kj9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 PHE A 200
VAL A 198
ILE A 276
ALA A 243
 ATP  A   1 (-4.9A)
ATP  A   1 (-3.9A)
None
None
 1.01A 4eyzB-1kj9A:
0.0		 4eyzB-1kj9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 PHE A 200
VAL A 198
ILE A 276
ALA A 247
 ATP  A   1 (-4.9A)
ATP  A   1 (-3.9A)
None
None
 0.98A 4eyzB-1kj9A:
0.0		 4eyzB-1kj9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 8 GLY A 196
VAL A 197
ILE A 168
PHE A 141
 EDO  A 402 ( 3.2A)
ATP  A   1 (-3.9A)
None
None
 0.82A 4fglD-1kj9A:
2.9		 4fglD-1kj9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 7 GLY A 196
VAL A 197
ILE A 168
PHE A 141
 EDO  A 402 ( 3.2A)
ATP  A   1 (-3.9A)
None
None
 0.77A 4fglC-1kj9A:
3.7		 4fglC-1kj9A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 7 VAL A 312
ALA A 211
GLY A 262
VAL A 209
 None
 0.87A 5fpdB-1kj9A:
undetectable		 5fpdB-1kj9A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 9 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.91A 5l5zK-1kj9A:
undetectable
5l5zL-1kj9A:
undetectable		 5l5zK-1kj9A:
20.76
5l5zL-1kj9A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 9 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.91A 5l5zY-1kj9A:
undetectable
5l5zZ-1kj9A:
undetectable		 5l5zY-1kj9A:
20.76
5l5zZ-1kj9A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 8 VAL A 388
ILE A 326
VAL A 344
HIS A 383
VAL A 340
 None
 1.34A 5l94A-1kj9A:
undetectable		 5l94A-1kj9A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 11 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.91A 6hwdK-1kj9A:
undetectable
6hwdL-1kj9A:
undetectable		 6hwdK-1kj9A:
12.21
6hwdL-1kj9A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		5 / 11 ALA A 369
THR A 370
ALA A 371
ALA A 377
GLY A 345
 None
 0.91A 6hwdY-1kj9A:
undetectable
6hwdZ-1kj9A:
undetectable		 6hwdY-1kj9A:
12.21
6hwdZ-1kj9A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1kj9 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE 2
(Escherichia
coli) 		4 / 7 ILE A 168
TRP A 178
GLU A 138
VAL A 145
 None
 0.68A 6j20A-1kj9A:
0.0		 6j20A-1kj9A:
21.89