SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 5 LEU A 180
LEU A 184
SER A 104
LEU A 138
 None
 1.01A 1a4lC-1kn3A:
undetectable		 1a4lC-1kn3A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 8 LEU A  68
SER A 109
ASP A  72
THR A 115
 None
 1.01A 1ig3A-1kn3A:
undetectable
1ig3B-1kn3A:
0.0		 1ig3A-1kn3A:
19.34
1ig3B-1kn3A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		3 / 3 PRO A 130
LEU A 131
GLN A 127
 None
 0.70A 3hznG-1kn3A:
0.0
3hznH-1kn3A:
0.0		 3hznG-1kn3A:
18.83
3hznH-1kn3A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 8 GLY A 147
THR A  69
LEU A  88
PHE A 149
 None
 1.23A 4m5mA-1kn3A:
undetectable		 4m5mA-1kn3A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 8 VAL A 124
VAL A  89
TYR A  64
LEU A  58
 None
 1.04A 4puoC-1kn3A:
undetectable		 4puoC-1kn3A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 6 ASN A  91
GLU A 135
TYR A 158
PHE A 154
 None
 1.01A 4twdB-1kn3A:
0.0
4twdC-1kn3A:
undetectable		 4twdB-1kn3A:
16.88
4twdC-1kn3A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 6 ASN A  91
GLU A 135
TYR A 158
PHE A 154
 None
 1.06A 4twdD-1kn3A:
undetectable
4twdE-1kn3A:
0.0		 4twdD-1kn3A:
16.88
4twdE-1kn3A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 6 ALA A 171
LEU A  41
TYR A  29
SER A 109
 None
 1.06A 5phhA-1kn3A:
undetectable		 5phhA-1kn3A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2
(Mus
musculus) 		4 / 6 ASP A 134
LEU A  88
SER A 104
PHE A 149
 None
 1.16A 6ekuA-1kn3A:
0.0		 6ekuA-1kn3A:
13.59