SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1knb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 1k2rA-1knbA:
0.0
1k2rB-1knbA:
0.0
1k2rA-1knbA:
18.98
1k2rB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 1k2tA-1knbA:
0.0
1k2tB-1knbA:
0.0
1k2tA-1knbA:
18.98
1k2tB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 1k2uA-1knbA:
0.0
1k2uB-1knbA:
0.0
1k2uA-1knbA:
18.98
1k2uB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
5 / 12 PHE A 554
THR A 403
LEU A 425
LEU A 473
ILE A 459
None
1.34A 1kqwA-1knbA:
0.0
1kqwA-1knbA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 1lzxA-1knbA:
0.0
1lzxB-1knbA:
0.0
1lzxA-1knbA:
18.98
1lzxB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 1lzxA-1knbA:
0.0
1lzxB-1knbA:
0.0
1lzxA-1knbA:
18.98
1lzxB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 1lzzA-1knbA:
0.0
1lzzB-1knbA:
0.0
1lzzA-1knbA:
18.98
1lzzB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 1lzzA-1knbA:
0.0
1lzzB-1knbA:
0.0
1lzzA-1knbA:
18.98
1lzzB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 1mmvA-1knbA:
0.0
1mmvB-1knbA:
0.0
1mmvA-1knbA:
18.98
1mmvB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 1mmvA-1knbA:
0.0
1mmvB-1knbA:
0.0
1mmvA-1knbA:
18.98
1mmvB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.46A 1mmwA-1knbA:
0.0
1mmwB-1knbA:
0.0
1mmwA-1knbA:
18.98
1mmwB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 1mmwA-1knbA:
0.0
1mmwB-1knbA:
0.0
1mmwA-1knbA:
18.98
1mmwB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 1om5A-1knbA:
0.0
1om5B-1knbA:
0.0
1om5A-1knbA:
18.93
1om5B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 1p6jA-1knbA:
undetectable
1p6jB-1knbA:
0.0
1p6jA-1knbA:
18.93
1p6jB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 1p6kA-1knbA:
0.0
1p6kB-1knbA:
0.0
1p6kA-1knbA:
18.93
1p6kB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 8 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 1rs6A-1knbA:
undetectable
1rs6B-1knbA:
undetectable
1rs6A-1knbA:
18.93
1rs6B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 8 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.49A 2g6hA-1knbA:
undetectable
2g6hB-1knbA:
undetectable
2g6hA-1knbA:
18.98
2g6hB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 2g6mA-1knbA:
undetectable
2g6mB-1knbA:
0.0
2g6mA-1knbA:
18.98
2g6mB-1knbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 2hx4A-1knbA:
undetectable
2hx4B-1knbA:
0.0
2hx4A-1knbA:
18.93
2hx4B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 3b3nA-1knbA:
undetectable
3b3nB-1knbA:
0.0
3b3nA-1knbA:
18.93
3b3nB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 3fc5A-1knbA:
0.0
3fc5B-1knbA:
0.0
3fc5A-1knbA:
18.93
3fc5B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.49A 3hsnA-1knbA:
0.0
3hsnB-1knbA:
undetectable
3hsnA-1knbA:
18.93
3hsnB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 3hsnA-1knbA:
0.0
3hsnB-1knbA:
0.0
3hsnA-1knbA:
18.93
3hsnB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.49A 3hsoA-1knbA:
0.0
3hsoB-1knbA:
0.0
3hsoA-1knbA:
18.93
3hsoB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 3hsoA-1knbA:
0.0
3hsoB-1knbA:
0.0
3hsoA-1knbA:
18.93
3hsoB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 3hspA-1knbA:
0.0
3hspB-1knbA:
0.0
3hspA-1knbA:
18.93
3hspB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 3hspA-1knbA:
0.0
3hspB-1knbA:
0.0
3hspA-1knbA:
18.93
3hspB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 3jt9A-1knbA:
0.0
3jt9B-1knbA:
0.0
3jt9A-1knbA:
18.93
3jt9B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 3jtaA-1knbA:
undetectable
3jtaB-1knbA:
undetectable
3jtaA-1knbA:
18.93
3jtaB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 3q9aA-1knbA:
0.0
3q9aB-1knbA:
0.0
3q9aA-1knbA:
18.93
3q9aB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.49A 3svpA-1knbA:
undetectable
3svpB-1knbA:
0.0
3svpA-1knbA:
18.93
3svpB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.46A 3ufoA-1knbA:
0.0
3ufoB-1knbA:
0.0
3ufoA-1knbA:
18.93
3ufoB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 3ufpA-1knbA:
undetectable
3ufpB-1knbA:
undetectable
3ufpA-1knbA:
18.93
3ufpB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.47A 3ufpA-1knbA:
0.0
3ufpB-1knbA:
0.0
3ufpA-1knbA:
18.93
3ufpB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 3ufrA-1knbA:
undetectable
3ufrB-1knbA:
0.0
3ufrA-1knbA:
18.93
3ufrB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 4d2yA-1knbA:
0.0
4d2yB-1knbA:
0.0
4d2yA-1knbA:
18.93
4d2yB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 4d31A-1knbA:
0.0
4d31B-1knbA:
0.0
4d31A-1knbA:
18.93
4d31B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 4imwA-1knbA:
0.0
4imwB-1knbA:
0.0
4imwA-1knbA:
18.93
4imwB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 4imwA-1knbA:
undetectable
4imwB-1knbA:
0.0
4imwA-1knbA:
18.93
4imwB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.48A 4kckA-1knbA:
undetectable
4kckB-1knbA:
0.0
4kckA-1knbA:
18.93
4kckB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
5 / 11 LEU A 413
LEU A 445
ALA A 440
VAL A 530
LEU A 522
None
1.16A 4p65C-1knbA:
undetectable
4p65D-1knbA:
undetectable
4p65J-1knbA:
undetectable
4p65L-1knbA:
undetectable
4p65C-1knbA:
6.70
4p65D-1knbA:
10.22
4p65J-1knbA:
10.22
4p65L-1knbA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 4 THR A 451
GLY A 443
ASP A 418
SER A 449
None
1.22A 4rfqA-1knbA:
undetectable
4rfqA-1knbA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.49A 4uh1A-1knbA:
0.0
4uh1B-1knbA:
0.0
4uh1A-1knbA:
18.93
4uh1B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 4upnA-1knbA:
undetectable
4upnB-1knbA:
0.0
4upnA-1knbA:
18.93
4upnB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 5 LYS A 528
PRO A 529
GLU A 566
TYR A 563
None
0.96A 4w5tA-1knbA:
undetectable
4w5tA-1knbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 LYS A 528
PRO A 529
GLU A 566
TYR A 563
None
1.04A 4z4cA-1knbA:
undetectable
4z4cA-1knbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 LYS A 528
PRO A 529
GLU A 566
TYR A 563
None
0.86A 4z4fA-1knbA:
undetectable
4z4fA-1knbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 LYS A 528
PRO A 529
GLU A 566
TYR A 563
None
0.98A 4z4gA-1knbA:
undetectable
4z4gA-1knbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.49A 5ad5A-1knbA:
0.0
5ad5B-1knbA:
0.0
5ad5A-1knbA:
18.93
5ad5B-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 5fvrA-1knbA:
0.0
5fvrB-1knbA:
0.0
5fvrA-1knbA:
18.93
5fvrB-1knbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 6 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.48A 5fvuA-1knbA:
0.0
5fvuB-1knbA:
0.0
5fvuA-1knbA:
19.17
5fvuB-1knbA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 TRP A 558
PHE A 568
GLU A 566
VAL A 530
None
1.50A 5fvuA-1knbA:
0.0
5fvuB-1knbA:
undetectable
5fvuA-1knbA:
19.17
5fvuB-1knbA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 LEU A 457
THR A 403
THR A 404
LEU A 413
None
0.89A 5jq7B-1knbA:
undetectable
5jq7B-1knbA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 8 THR A 535
SER A 553
THR A 533
SER A 555
None
0.95A 5l4eA-1knbA:
undetectable
5l4eB-1knbA:
undetectable
5l4eC-1knbA:
undetectable
5l4eD-1knbA:
undetectable
5l4eE-1knbA:
undetectable
5l4eA-1knbA:
21.77
5l4eB-1knbA:
21.77
5l4eC-1knbA:
21.77
5l4eD-1knbA:
21.77
5l4eE-1knbA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUO_D_PFLD402_1
(PROTON-GATED ION
CHANNEL)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
5 / 9 THR A 535
SER A 553
ILE A 458
THR A 533
SER A 555
None
0.90A 5muoA-1knbA:
0.4
5muoB-1knbA:
undetectable
5muoC-1knbA:
0.5
5muoD-1knbA:
0.0
5muoE-1knbA:
0.0
5muoA-1knbA:
20.22
5muoB-1knbA:
20.22
5muoC-1knbA:
20.22
5muoD-1knbA:
20.22
5muoE-1knbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
5 / 12 LEU A 423
LEU A 425
LEU A 473
ALA A 494
MET A 498
None
1.01A 5og9B-1knbA:
undetectable
5og9B-1knbA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 LYS A 528
PRO A 529
GLU A 566
TYR A 563
None
0.82A 5t7bA-1knbA:
undetectable
5t7bA-1knbA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
1knb ADENOVIRUS TYPE 5
FIBER PROTEIN

(Human
mastadenovirus
C)
4 / 7 VAL A 530
TRP A 558
PHE A 568
GLU A 566
None
1.50A 5vuwA-1knbA:
undetectable
5vuwB-1knbA:
0.0
5vuwA-1knbA:
19.17
5vuwB-1knbA:
19.17