SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		6 / 12 GLY A 106
ASN A  86
ILE A 116
LEU A  57
VAL A 141
LEU A 129
 None
 1.48A 1r30A-1kngA:
undetectable		 1r30A-1kngA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		6 / 12 GLY A 106
ASN A  86
ILE A 116
LEU A  57
VAL A 141
LEU A 129
 None
 1.48A 1r30B-1kngA:
undetectable		 1r30B-1kngA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		4 / 5 LEU A  57
ASP A 142
GLY A 152
ILE A 116
 None
 0.86A 2aohB-1kngA:
undetectable		 2aohB-1kngA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.87A 2q63A-1kngA:
undetectable		 2q63A-1kngA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 10 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3em3A-1kngA:
undetectable		 3em3A-1kngA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3ndtB-1kngA:
undetectable		 3ndtB-1kngA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 11 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.89A 3nu3B-1kngA:
undetectable		 3nu3B-1kngA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.89A 3nu4B-1kngA:
undetectable		 3nu4B-1kngA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.87A 3nu5A-1kngA:
undetectable		 3nu5A-1kngA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3nujB-1kngA:
undetectable		 3nujB-1kngA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3nuoB-1kngA:
undetectable		 3nuoB-1kngA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3oxvA-1kngA:
undetectable		 3oxvA-1kngA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.91A 3oxvC-1kngA:
undetectable		 3oxvC-1kngA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.87A 3s54A-1kngA:
undetectable		 3s54A-1kngA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A 102
LEU A 105
GLY A 106
VAL A  85
VAL A  70
 None
 1.00A 4ok1A-1kngA:
undetectable		 4ok1A-1kngA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		4 / 8 ILE A 168
LEU A 186
LEU A 172
PHE A 160
 None
 0.83A 4r38B-1kngA:
undetectable		 4r38B-1kngA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		4 / 8 ILE A 168
LEU A 186
LEU A 172
PHE A 160
 None
 0.87A 4r38D-1kngA:
undetectable		 4r38D-1kngA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.92A 4rvjB-1kngA:
undetectable		 4rvjB-1kngA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 9 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.92A 4rvjD-1kngA:
undetectable		 4rvjD-1kngA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 LEU A  57
ASP A 142
GLY A 145
GLY A 152
ILE A 116
 None
 0.89A 5t8hB-1kngA:
undetectable		 5t8hB-1kngA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY
(Bradyrhizobium
japonicum) 		5 / 12 ALA A 147
GLY A 115
GLY A 140
ARG A 138
VAL A  87
 None
 1.26A 6clxA-1kngA:
undetectable		 6clxA-1kngA:
21.29