SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1knl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 SER A  37
GLY A  38
GLN A  42
 None
 0.59A 3v4tH-1knlA:
undetectable		 3v4tH-1knlA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.59A 3w9tA-1knlA:
18.2		 3w9tA-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.58A 3w9tB-1knlA:
6.6		 3w9tB-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.59A 3w9tC-1knlA:
15.0		 3w9tC-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 ASP A 101
GLY A 104
TYR A 116
 None
 0.53A 3w9tC-1knlA:
15.0		 3w9tC-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.58A 3w9tD-1knlA:
19.0		 3w9tD-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.59A 3w9tE-1knlA:
18.9		 3w9tE-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.58A 3w9tF-1knlA:
19.0		 3w9tF-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 ASP A 101
GLY A 104
TYR A 116
 None
 0.53A 3w9tG-1knlA:
19.0		 3w9tG-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 ASP A 101
VAL A 103
GLY A 104
TYR A 116
 None
 0.58A 3w9tG-1knlA:
19.0		 3w9tG-1knlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		4 / 5 GLY A 106
ILE A 113
LYS A  69
GLN A 114
 None
 0.77A 4ma8C-1knlA:
undetectable		 4ma8C-1knlA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 SER A  13
ASP A  21
ASP A  34
 None
GOL  A 531 (-4.1A)
None
 0.79A 4uckA-1knlA:
undetectable		 4uckA-1knlA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 1knl ENDO-1,4-BETA-XYLANA
SE A
(Streptomyces
lividans) 		3 / 3 THR A  46
ASP A  47
ALA A  48
 None
 0.00A 5g5gB-1knlA:
undetectable		 5g5gB-1knlA:
19.16