SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1knr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 ILE A 500
VAL A 210
LEU A 443
ALA A 226
ILE A 474
 None
 0.91A 1epbA-1knrA:
undetectable		 1epbA-1knrA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 ILE A 500
VAL A 210
LEU A 443
ALA A 226
ILE A 474
 None
 0.98A 1epbB-1knrA:
0.0		 1epbB-1knrA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 1gtnB-1knrA:
undetectable
1gtnC-1knrA:
undetectable		 1gtnB-1knrA:
9.07
1gtnC-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.14A 1gtnH-1knrA:
undetectable
1gtnI-1knrA:
undetectable		 1gtnH-1knrA:
9.07
1gtnI-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 1gtnO-1knrA:
undetectable
1gtnP-1knrA:
undetectable		 1gtnO-1knrA:
9.07
1gtnP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
THR A 119
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.24A 1gtnO-1knrA:
undetectable
1gtnP-1knrA:
undetectable		 1gtnO-1knrA:
9.07
1gtnP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 9 GLY A 264
THR A 119
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.22A 1gtnQ-1knrA:
undetectable
1gtnR-1knrA:
undetectable		 1gtnQ-1knrA:
9.07
1gtnR-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.15A 1gtnU-1knrA:
undetectable
1gtnV-1knrA:
undetectable		 1gtnU-1knrA:
9.07
1gtnV-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 GLY A 181
ALA A 182
ASP A 164
THR A 160
VAL A 184
 None
 0.96A 1k6cB-1knrA:
undetectable		 1k6cB-1knrA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.03A 1p6kA-1knrA:
0.0		 1p6kA-1knrA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.05A 1p6kB-1knrA:
0.0		 1p6kB-1knrA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R9O_A_FLPA501_1
(CYTOCHROME P450 2C9)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 VAL A 140
LEU A  25
GLY A  17
ALA A  18
LEU A  97
 None
None
FAD  A 800 ( 3.7A)
FAD  A 800 (-4.4A)
None
 1.09A 1r9oA-1knrA:
undetectable		 1r9oA-1knrA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 HIS A 244
PRO A 245
SER A 389
THR A 119
 CL  A 541 (-4.8A)
None
FAD  A 800 (-4.3A)
None
 1.21A 1rg9A-1knrA:
undetectable		 1rg9A-1knrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 HIS A 244
PRO A 245
SER A 389
THR A 119
 CL  A 541 (-4.8A)
None
FAD  A 800 (-4.3A)
None
 1.21A 1rg9B-1knrA:
undetectable		 1rg9B-1knrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 HIS A 244
PRO A 245
SER A 389
THR A 119
 CL  A 541 (-4.8A)
None
FAD  A 800 (-4.3A)
None
 1.22A 1rg9D-1knrA:
undetectable		 1rg9D-1knrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 0.92A 1rs6A-1knrA:
undetectable		 1rs6A-1knrA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 0.97A 1rs6B-1knrA:
0.0		 1rs6B-1knrA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 LEU A 490
LEU A 487
SER A 484
 None
 0.67A 1tlmA-1knrA:
0.0		 1tlmA-1knrA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.17A 1utdT-1knrA:
undetectable
1utdU-1knrA:
undetectable		 1utdT-1knrA:
9.07
1utdU-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
THR A 119
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 1utdT-1knrA:
undetectable
1utdU-1knrA:
undetectable		 1utdT-1knrA:
9.07
1utdU-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 8 ILE A  53
PHE A 104
ARG A 138
THR A 142
LEU A 144
 None
 1.34A 1v55N-1knrA:
2.2
1v55W-1knrA:
undetectable		 1v55N-1knrA:
20.83
1v55W-1knrA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 HIS A 382
ALA A  82
GLY A  74
GLY A 383
LEU A 513
 None
 0.84A 1x1aA-1knrA:
2.3		 1x1aA-1knrA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.04A 1zzqA-1knrA:
0.0		 1zzqA-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.08A 1zzqB-1knrA:
0.0		 1zzqB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.08A 1zzuB-1knrA:
0.0		 1zzuB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 THR A 353
ASN A 241
ARG A 444
ALA A 350
THR A 214
 None
 1.29A 2axnA-1knrA:
undetectable		 2axnA-1knrA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 8 ILE A  53
PHE A 104
ARG A 138
THR A 142
LEU A 144
 None
 1.34A 2einA-1knrA:
0.0
2einJ-1knrA:
undetectable		 2einA-1knrA:
20.83
2einJ-1knrA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 6 ARG A 271
ASP A 273
THR A 275
ASP A 280
 None
 1.25A 2j2pE-1knrA:
undetectable
2j2pF-1knrA:
0.0		 2j2pE-1knrA:
16.44
2j2pF-1knrA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 11 LEU A 202
ILE A  14
GLY A  15
GLY A  20
LEU A 370
 None
FAD  A 800 (-4.6A)
FAD  A 800 (-3.1A)
None
None
 0.95A 2qmmA-1knrA:
undetectable
2qmmB-1knrA:
undetectable		 2qmmA-1knrA:
16.45
2qmmB-1knrA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 SER A 115
TYR A 116
HIS A 117
 None
 0.82A 2r2vD-1knrA:
undetectable		 2r2vD-1knrA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 8 ILE A  53
PHE A 104
ARG A 138
THR A 142
LEU A 144
 None
 1.40A 3abmN-1knrA:
3.7
3abmW-1knrA:
0.0		 3abmN-1knrA:
20.83
3abmW-1knrA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 8 ILE A  53
PHE A 104
ARG A 138
THR A 142
LEU A 144
 None
 1.34A 3asoN-1knrA:
2.3
3asoW-1knrA:
0.0		 3asoN-1knrA:
20.83
3asoW-1knrA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 TRP A 183
VAL A 367
ARG A 364
 None
 0.85A 3b0wA-1knrA:
0.0		 3b0wA-1knrA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 ASN A 186
TRP A 185
VAL A 184
VAL A 163
LEU A 488
 None
 1.30A 3casA-1knrA:
undetectable		 3casA-1knrA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 ASP A 134
GLN A  50
MET A 327
GLU A 121
 None
None
None
CL  A 541 ( 4.2A)
 1.37A 3dh0A-1knrA:
2.4		 3dh0A-1knrA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		6 / 12 ALA A  19
GLY A 374
LEU A 396
LEU A 392
SER A 391
GLY A  15
 FAD  A 800 (-3.4A)
FAD  A 800 (-3.5A)
None
FAD  A 800 (-3.4A)
FAD  A 800 (-2.6A)
FAD  A 800 (-3.1A)
 1.35A 3g2oA-1knrA:
2.9		 3g2oA-1knrA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 MET A 358
CYH A 503
PRO A 528
 None
 1.04A 3h52C-1knrA:
0.0		 3h52C-1knrA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 LEU A 238
ILE A 225
SER A 220
SER A 208
GLY A 222
 None
 1.22A 3ijxB-1knrA:
undetectable
3ijxD-1knrA:
undetectable		 3ijxB-1knrA:
18.38
3ijxD-1knrA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 6 PHE A 277
ILE A 297
ALA A 296
ALA A 288
 None
 0.77A 3mdrB-1knrA:
undetectable		 3mdrB-1knrA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.15A 3n62B-1knrA:
0.0		 3n62B-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.29A 3n66B-1knrA:
0.0		 3n66B-1knrA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 HIS A 414
ARG A 178
GLU A 368
 None
 1.04A 3qf1A-1knrA:
0.0		 3qf1A-1knrA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		3 / 3 ASN A 492
ALA A 226
ARG A 230
 None
 0.90A 3tj7C-1knrA:
0.0
3tj7D-1knrA:
0.0		 3tj7C-1knrA:
17.22
3tj7D-1knrA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 8 GLY A 356
GLY A 355
GLY A 222
ILE A 500
VAL A 496
 None
NA  A 542 (-4.4A)
None
None
None
 1.26A 3v1nA-1knrA:
undetectable		 3v1nA-1knrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 PHE A 446
TYR A 450
MET A 505
GLU A 442
 None
 1.11A 4a97C-1knrA:
6.3		 4a97C-1knrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 ARG A 290
GLU A 260
GLU A 121
GLY A 123
HIS A 351
 CL  A 541 ( 4.6A)
None
CL  A 541 ( 4.2A)
None
FAD  A 800 (-4.2A)
 1.37A 4ffwB-1knrA:
undetectable		 4ffwB-1knrA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB806_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 7 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.37A 4kcnB-1knrA:
0.0		 4kcnB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 GLY A 181
ALA A 182
ASP A 164
ILE A  13
THR A 160
 None
 1.03A 4njvA-1knrA:
undetectable		 4njvA-1knrA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 9 VAL A 184
ILE A 225
ALA A 228
VAL A 200
ALA A 182
 None
 1.31A 4oqrA-1knrA:
0.0		 4oqrA-1knrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 LEU A 370
LEU A 202
VAL A 235
LEU A 238
LEU A 499
 None
 1.13A 4po0A-1knrA:
2.4		 4po0A-1knrA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 11 SER A 208
THR A 214
ALA A 388
GLU A 375
GLY A  44
 None
None
None
FAD  A 800 ( 3.8A)
FAD  A 800 (-3.8A)
 1.32A 4zjoD-1knrA:
undetectable		 4zjoD-1knrA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 ILE A 225
ALA A 226
ARG A 230
ALA A 162
ASN A 492
 None
None
None
FAD  A 800 (-3.5A)
None
 1.44A 4zo1X-1knrA:
0.0		 4zo1X-1knrA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 7 ILE A  53
PHE A 104
ARG A 138
THR A 142
LEU A 144
 None
 1.43A 5b1bN-1knrA:
0.0
5b1bW-1knrA:
0.0		 5b1bN-1knrA:
20.83
5b1bW-1knrA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 6 ASP A 405
ARG A 364
GLY A 369
GLU A 368
 None
 1.08A 5cdqA-1knrA:
3.3
5cdqC-1knrA:
3.3
5cdqD-1knrA:
undetectable		 5cdqA-1knrA:
23.47
5cdqC-1knrA:
23.47
5cdqD-1knrA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eeuF-1knrA:
undetectable
5eeuG-1knrA:
0.0		 5eeuF-1knrA:
9.07
5eeuG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eeuO-1knrA:
undetectable
5eeuP-1knrA:
undetectable		 5eeuO-1knrA:
9.07
5eeuP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.18A 5eeuQ-1knrA:
undetectable
5eeuR-1knrA:
undetectable		 5eeuQ-1knrA:
9.07
5eeuR-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eevF-1knrA:
undetectable
5eevG-1knrA:
0.0		 5eevF-1knrA:
9.07
5eevG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eevO-1knrA:
undetectable
5eevP-1knrA:
undetectable		 5eevO-1knrA:
9.07
5eevP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eevQ-1knrA:
undetectable
5eevR-1knrA:
undetectable		 5eevQ-1knrA:
9.07
5eevR-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eewF-1knrA:
undetectable
5eewG-1knrA:
0.0		 5eewF-1knrA:
9.07
5eewG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eewO-1knrA:
undetectable
5eewP-1knrA:
undetectable		 5eewO-1knrA:
9.07
5eewP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eewQ-1knrA:
undetectable
5eewR-1knrA:
undetectable		 5eewQ-1knrA:
9.07
5eewR-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eexF-1knrA:
undetectable
5eexG-1knrA:
0.0		 5eexF-1knrA:
9.07
5eexG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eexO-1knrA:
undetectable
5eexP-1knrA:
undetectable		 5eexO-1knrA:
9.07
5eexP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eeyF-1knrA:
undetectable
5eeyG-1knrA:
0.0		 5eeyF-1knrA:
9.07
5eeyG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eeyO-1knrA:
undetectable
5eeyP-1knrA:
undetectable		 5eeyO-1knrA:
9.07
5eeyP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5eezF-1knrA:
undetectable
5eezG-1knrA:
0.0		 5eezF-1knrA:
9.07
5eezG-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5eezO-1knrA:
undetectable
5eezP-1knrA:
undetectable		 5eezO-1knrA:
9.07
5eezP-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5ef0F-1knrA:
undetectable
5ef0G-1knrA:
0.0		 5ef0F-1knrA:
9.07
5ef0G-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5ef0O-1knrA:
undetectable
5ef0P-1knrA:
undetectable		 5ef0O-1knrA:
9.07
5ef0P-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.14A 5ef1F-1knrA:
undetectable
5ef1G-1knrA:
0.0		 5ef1F-1knrA:
9.07
5ef1G-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5ef1O-1knrA:
undetectable
5ef1P-1knrA:
undetectable		 5ef1O-1knrA:
9.07
5ef1P-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5ef2F-1knrA:
undetectable
5ef2G-1knrA:
0.0		 5ef2F-1knrA:
9.07
5ef2G-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.19A 5ef2O-1knrA:
undetectable
5ef2P-1knrA:
undetectable		 5ef2O-1knrA:
9.07
5ef2P-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 THR A 259
SER A 389
ALA A 388
GLY A 264
THR A 119
 CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
None
None
 1.13A 5ef3F-1knrA:
undetectable
5ef3G-1knrA:
0.0		 5ef3F-1knrA:
9.07
5ef3G-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 GLY A 264
HIS A 131
THR A 259
SER A 389
ALA A 388
 None
None
CL  A 541 (-3.9A)
FAD  A 800 (-4.3A)
None
 1.20A 5ef3O-1knrA:
undetectable
5ef3P-1knrA:
undetectable		 5ef3O-1knrA:
9.07
5ef3P-1knrA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 5 PHE A 446
ILE A 467
MET A 447
ARG A 466
 None
 1.41A 5jm4A-1knrA:
undetectable		 5jm4A-1knrA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 9 LEU A 202
ILE A  14
GLY A  15
GLY A  20
LEU A 370
 None
FAD  A 800 (-4.6A)
FAD  A 800 (-3.1A)
None
None
 0.80A 5o96A-1knrA:
undetectable
5o96B-1knrA:
undetectable		 5o96A-1knrA:
17.84
5o96B-1knrA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 LEU A 202
ILE A  14
GLY A  15
GLY A  20
LEU A 370
 None
FAD  A 800 (-4.6A)
FAD  A 800 (-3.1A)
None
None
 0.79A 5twjA-1knrA:
undetectable		 5twjA-1knrA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 LEU A 202
ILE A  14
GLY A  15
GLY A  20
LEU A 370
 None
FAD  A 800 (-4.6A)
FAD  A 800 (-3.1A)
None
None
 0.85A 5twjB-1knrA:
undetectable		 5twjB-1knrA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 11 LEU A 202
ILE A  14
GLY A  15
GLY A  20
LEU A 370
 None
FAD  A 800 (-4.6A)
FAD  A 800 (-3.1A)
None
None
 0.84A 5twjD-1knrA:
undetectable		 5twjD-1knrA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 5 LEU A 499
LEU A 238
MET A 447
GLN A 471
 None
 0.91A 5uc3A-1knrA:
0.0		 5uc3A-1knrA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.33A 5vunB-1knrA:
0.0		 5vunB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.29A 5vuoB-1knrA:
0.0		 5vuoB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W8A_A_SAMA300_0
(AUTOINDUCER SYNTHASE)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 THR A 143
LEU A 144
PHE A 104
ILE A  53
GLU A 139
 None
 1.25A 5w8aA-1knrA:
undetectable		 5w8aA-1knrA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEO_A_CYZA1302_1
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 SER A  45
ILE A 225
SER A 220
SER A 208
GLY A 222
 FAD  A 800 (-3.3A)
None
None
None
None
 1.34A 5weoA-1knrA:
3.3
5weoD-1knrA:
3.3		 5weoA-1knrA:
19.01
5weoD-1knrA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 ILE A 313
GLN A  50
PRO A 245
THR A 246
LEU A 311
 None
 1.23A 5xxiA-1knrA:
0.0		 5xxiA-1knrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 8 SER A 208
ASN A 241
GLN A 242
ASN A 216
 None
None
None
FAD  A 800 (-4.1A)
 1.32A 6auuB-1knrA:
0.0		 6auuB-1knrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 10 LEU A 257
HIS A 244
ALA A 247
PRO A 217
SER A 220
 FAD  A 800 (-4.3A)
CL  A 541 (-4.8A)
None
None
None
 1.50A 6b89A-1knrA:
undetectable		 6b89A-1knrA:
10.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 GLY A 222
GLY A 224
VAL A 496
LEU A 499
ILE A 500
 None
 0.92A 6ectA-1knrA:
2.2		 6ectA-1knrA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		5 / 12 GLY A 222
GLY A 224
VAL A 496
LEU A 499
ILE A 500
 None
 0.94A 6ecxA-1knrA:
2.3		 6ecxA-1knrA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 1knr L-ASPARTATE OXIDASE
(Escherichia
coli) 		4 / 7 GLY A 222
HIS A 351
ASN A 216
GLY A  44
 None
FAD  A 800 (-4.2A)
FAD  A 800 (-4.1A)
FAD  A 800 (-3.8A)
 0.97A 6n7fA-1knrA:
10.6		 6n7fA-1knrA:
9.02