SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1kny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 5 ASP A 200
HIS A 181
HIS A 241
HIS A 180
 None
 1.22A 1ei6A-1knyA:
undetectable		 1ei6A-1knyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 6 GLY A 114
VAL A  56
ALA A  33
SER A 112
 None
 1.02A 1p6kA-1knyA:
0.3		 1p6kA-1knyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		3 / 3 PRO A  97
GLY A 178
TYR A 185
 None
 0.74A 2vouA-1knyA:
undetectable		 2vouA-1knyA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 6 GLY A  41
GLN A  43
ILE A 106
VAL A  36
 None
 1.16A 3kvvB-1knyA:
undetectable		 3kvvB-1knyA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 6 GLY A  41
GLN A  43
ILE A 106
VAL A  36
 None
 1.13A 3kvvC-1knyA:
undetectable		 3kvvC-1knyA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 9 TYR A 110
ILE A  34
ILE A 109
MET A  53
ILE A  19
 None
 1.19A 3p4wB-1knyA:
2.5		 3p4wB-1knyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 10 TYR A 110
ILE A  34
ILE A 109
MET A  53
ILE A  19
 None
 1.19A 3p4wD-1knyA:
2.5		 3p4wD-1knyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 10 TYR A 110
ILE A  34
ILE A 109
MET A  53
ILE A  19
 None
 1.21A 3p4wE-1knyA:
2.4		 3p4wE-1knyA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qvlV-1knyA:
undetectable
4qvlb-1knyA:
undetectable		 4qvlV-1knyA:
25.63
4qvlb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qvlH-1knyA:
undetectable
4qvlN-1knyA:
undetectable		 4qvlH-1knyA:
25.63
4qvlN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 4qvmV-1knyA:
undetectable
4qvmb-1knyA:
undetectable		 4qvmV-1knyA:
25.63
4qvmb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 4qvmH-1knyA:
undetectable
4qvmN-1knyA:
undetectable		 4qvmH-1knyA:
25.63
4qvmN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 4qvpV-1knyA:
undetectable
4qvpb-1knyA:
undetectable		 4qvpV-1knyA:
25.63
4qvpb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 4qvpH-1knyA:
undetectable
4qvpN-1knyA:
undetectable		 4qvpH-1knyA:
25.63
4qvpN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 4qvqV-1knyA:
undetectable
4qvqb-1knyA:
undetectable		 4qvqV-1knyA:
25.63
4qvqb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.38A 4qvqH-1knyA:
undetectable
4qvqN-1knyA:
undetectable		 4qvqH-1knyA:
25.63
4qvqN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qvwV-1knyA:
undetectable
4qvwb-1knyA:
undetectable		 4qvwV-1knyA:
25.63
4qvwb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qvwH-1knyA:
undetectable
4qvwN-1knyA:
undetectable		 4qvwH-1knyA:
25.63
4qvwN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qw0V-1knyA:
undetectable
4qw0b-1knyA:
undetectable		 4qw0V-1knyA:
25.63
4qw0b-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 4qw0H-1knyA:
undetectable
4qw0N-1knyA:
undetectable		 4qw0H-1knyA:
25.63
4qw0N-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 4qw1V-1knyA:
undetectable
4qw1b-1knyA:
undetectable		 4qw1V-1knyA:
25.63
4qw1b-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 4qw1H-1knyA:
undetectable
4qw1N-1knyA:
undetectable		 4qw1H-1knyA:
25.63
4qw1N-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 4qw3V-1knyA:
undetectable
4qw3b-1knyA:
undetectable		 4qw3V-1knyA:
25.63
4qw3b-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 4qw3H-1knyA:
undetectable
4qw3N-1knyA:
undetectable		 4qw3H-1knyA:
25.63
4qw3N-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.40A 4qwuV-1knyA:
undetectable
4qwub-1knyA:
undetectable		 4qwuV-1knyA:
25.63
4qwub-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.40A 4qwuH-1knyA:
undetectable
4qwuN-1knyA:
undetectable		 4qwuH-1knyA:
25.63
4qwuN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 12 ALA A 172
LEU A 176
LEU A 143
LEU A 208
PRO A 202
 None
 1.13A 4xi3D-1knyA:
undetectable		 4xi3D-1knyA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 5bxnV-1knyA:
undetectable
5bxnb-1knyA:
undetectable		 5bxnV-1knyA:
25.63
5bxnb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.38A 5bxnH-1knyA:
undetectable
5bxnN-1knyA:
undetectable		 5bxnH-1knyA:
25.63
5bxnN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.36A 5cz7H-1knyA:
undetectable
5cz7N-1knyA:
undetectable		 5cz7H-1knyA:
25.63
5cz7N-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.34A 5d0xV-1knyA:
undetectable
5d0xb-1knyA:
undetectable		 5d0xV-1knyA:
25.63
5d0xb-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.35A 5d0xH-1knyA:
undetectable
5d0xN-1knyA:
undetectable		 5d0xH-1knyA:
25.63
5d0xN-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.38A 5l66V-1knyA:
undetectable
5l66b-1knyA:
undetectable		 5l66V-1knyA:
25.63
5l66b-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 SER A  49
THR A 186
THR A 187
ARG A   9
GLY A  41
 APC  A 556 (-2.9A)
None
APC  A 556 (-3.4A)
None
None
 1.37A 5l66H-1knyA:
undetectable
5l66N-1knyA:
undetectable		 5l66H-1knyA:
25.63
5l66N-1knyA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		3 / 3 ALA A  89
VAL A  56
TYR A  80
 None
 0.69A 5zmqH-1knyA:
undetectable		 5zmqH-1knyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 12 GLY A 173
VAL A 191
THR A 238
GLY A 242
HIS A 181
 None
 1.14A 6gngA-1knyA:
undetectable		 6gngA-1knyA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 1kny KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE
(Staphylococcus
aureus) 		3 / 3 TRP A  68
ILE A  19
GLU A  52
 None
None
MG  A 603 ( 2.0A)
 0.86A 6hcxA-1knyA:
undetectable		 6hcxA-1knyA:
12.24